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3972728
Noradrenalina(NA)
Description
Mind Map on Noradrenalina(NA), created by L'uan Melo on 06/11/2015.
No tags specified
agonista adreergicoas
Mind Map by
L'uan Melo
, updated more than 1 year ago
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Created by
L'uan Melo
about 9 years ago
17
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Resource summary
Noradrenalina(NA)
VRAM-2
Transp de V. Sinaptica
Reserpina(farmacoinibidor)
Sintetizado pela dopamina-B-hidroxilase
Recaptura/Inativação
NET(TRansportador ) e DAT
Inibido pela cocaina
OCT3
Leva a NA pros tecidos
extraneuronal
inibido por corticostenona e isocianinas
Degradação
MAO
Na mitocrondria
Inativação completa
COMT
T. Neuronal e não neuronal
Hidroxilação
Ausente nos neurônios noradrenérgicos
Alfa 2
Inibitoria
Autoreceptor
Pre-sinaptico
Alfa 1
Contração
Bronquio
Iris
Utero
Musculos
Bexiga
Relaxamento
TGI
Beta 1
Coração
Aumento do debito
Aumento da força
Beta 2
Relaxamento
Vasos
Bronquios
TGI
Utero
Bexiga
Musculo ciliar
Beta 3
Adipositos e causam a lipolise
Farmacos
Propanolol
Annotations:
ANtagonista beta adrenergico ( reduz frequencia cardicaca e debito cardiaco )
Metaraminol
Annotations:
Agonista alfa 1 seletivo , causando contração de vasos cardiacos
Clonidina
Annotations:
agonista de alfa2
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