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6090855
HIPERCALCEMIA
Description
Mind Map on HIPERCALCEMIA, created by alejandro zuluaga on 22/08/2016.
Mind Map by
alejandro zuluaga
, updated more than 1 year ago
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Created by
alejandro zuluaga
over 8 years ago
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Resource summary
HIPERCALCEMIA
Definición: aumento del calcio sérico por encima de
Mecanismo
Aumento de proteinas plasmaticas: falsa hipercalcemia
Correccion con albúmina: 1g/dL aumenta 0.2 a 0.25 mmol/L (0.8 a 1.0 mg/dL)
ERC??
Incemento de Ca ionizado: verdadera hipercalcemia
Causas
Incremento en la absorcion intestinal
Estimulacion absorcion osea
Descenso en la excrecion urinaria
Neoplasias
Mama- Bronquio- riñon- tiroides
Mx
Metastasi: invasion directa
Factores que estimulan la accion osteoclastica
PTHrP, factor activador de osteoclastos, factor trasformante de crecimiento, PGE, calcitriol y FNT alfa
Hiperparatiroidismo primario: segunda causa
Adenoma de paratiroide: 80% Hiperplasia difusa de todas las celulas 10% Cancer de paratiroides 5%
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