Constitute Approximately 20-40% Outpatient Visits,
>85% Include Naso-pharyngitis,Pharyngitis, Tonsillitis,
Otitis Media, Majority of Illness Presents as Viral in
Nature, Predominant Bacterial Causes Include
Streptococcus and Staphylococcus Species.
Inappropriate Stewardship of Antibiotic Use Contributes to the
Development of Resistant Species of Bacteria, Hand-washing remains
the most Effective Means of Controlling Infection
Pathophysiology
Pathogenic Inoculation followed by overwhelming
multiple immune barriers, initiating an active
immune response mediated by cytokines, active
cellular response to inflammation including
neutrophils, macrophages, monocytes, and
eosinophils.
Risk Factors
Immature Immunity, Repetitive Exposure to Bacterial or Viral Pathogens,
Repetitive Exposure to Second-Hand Smoke, Pre-Exisiting Disease Process,
Exposure to an Infectious Person
Children are Especially Venerable in Group Care
situations, but over-zealous sanitation efforts may leave
immune systems unchallenged.
Clinical Presentation, Positive Cultures or Viral
Testing
Increased White Count, Manual Differential
Demonstrates a 'Shift to the Left' with immature
cells present
Fever, Pain, Malaise
Adaptive Responses
Fever (Anti-Microbial Effect), Increased Rate of Respiration and Heart
(Response to Pain), Inflamed Lymph Nodes (Active Inflammatory Response to
Begin Clearing Infection), Exudate (Active Cellular Involvement), Erythema
(Active Isolation of Inflammatory or Infectious Process)
References Deglin, J. H., Vallerand, A. H., & Sanoski, C. A. (2011). Davis's
Drug Guide for Nurses (12th ed.). Philadelphia, PA: F.A.Davis Company.
Holmes, S., & Scullion, J. (2013, November). Prescribing for upper
respiratory tract infection. . Retrieved from CINAHL. Huether, S., &
McCance, K. (2012). Understanding Pathophysiology (5th ed., pp.
1049-1050). St Louis, MO: Laureate Education.