AKA diabetes mellitus, a group of metabolic diseases in
which the person has high blood glucose (blood sugar)
Risk factors
Family history
Disease of the pancreas
Obesity or being overweight
Age
Unhealthy diet
Sedentary lifestyle
Clinical manifestations
Frequent urination
Excessive thirst/hunger
Unexplained weight loss
Sudden vision changes
Feeling very tired most of the time
More infections than usual
Pathophysiology
The immune system attacks and destroys the insulin producing
beta cells of the pancreas, leading to complete insulin deficiency
A relative deficiency of insulin and not an absolute deficiency. This means
that the body is unable to produce adequate insulin to meet the needs.
There is Beta cell deficiency coupled with peripheral insulin resistance
Peripheral insulin resistance means that although blood levels of
insulin are high there is no hypoglycemia or low blood sugar
When there are excessive counter-insulin hormones during pregnancy. This
leads to a state of insulin resistance and high blood sugar in the mother
Management
Surgical
Roux-en-gastric bypass
Sleev gastrectomy
Adjustable gastric band
Medical
Self-Monitoring of Blood Glucose
Oral medication that works on producing insulin
Insulin injections for life
Complications
Retinopathy - disease of the eye
Nephropathy - disease of the kidneys
Neuropathy - disease of the nerves
Angina pectoris and heart attack
Transient ischemic attacks and strokes
Formation of ketone bodies leading to ketoacidosis
Types
Diabetes type 1
The body does not produce insulin
Diabetes type 2
The body does not produce enough insulin for proper function
Gestational Diabetes
Affects females during pregnancy
Causes
Insulin production is inadequate.
The body's cells do not respond properly to insulin