11327221
Description
Mind Map by shahid alzaghari, updated more than 1 year ago
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Created by shahid alzaghari
almost 7 years ago
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Yasser is falling
behind
- Yasser 2 years 1 month old
- Main diagnosis
- Growth Hormone Deficiency
- Growth hormone
- Produced (somatotrophs) and secreted in
- exerts effects on almost all tissues
- Adipose tissue
- Cartilage
- Bone
- Liver
- Muscles
- Indirectly
- Directly
- Adipose tissue
- 191 amino acids-polypeptide
chain-2 internal disulfide bridges
- Produced (somatotrophs) and secreted in
- The pituitary gland does not make enough growth hormone
- Criteria to Initiate
Evaluation for GHD
- Criteria to Initiate
Evaluation for GHD
- Clinical presentation:
- Congenital
- Exaggerated jaundice in
the first days
- Growth failure
- Slower developmental milestones
- Reduced energy
- Impaired concentration
- Memory loss
- Memory loss
- Impaired concentration
- Reduced energy
- Slower developmental milestones
- Exaggerated jaundice in
the first days
- Acquired
- Delayed puberty
- Baldness in men
- Reduced bone mass
and osteoperosis
- Reduced energy
- Increased body fats
(around waist line)
- Increased body fats
(around waist line)
- Reduced energy
- Reduced bone mass
and osteoperosis
- Baldness in men
- Delayed puberty
- Congenital
- Epidemiology
- 3-10 in every 100 babies are born
smaller than normal
- 3-10 in every 100 babies are born
smaller than normal
- Investications:
- Growth chart
- Normal
- GHD
- Normal
- Physical examination
- Tests:
- Blood tests
- GH
- IGF-1
- CBC
- Serum protein
- GH
- Karyotyping
- X-ray
- Left wrist
- Left wrist
- Blood tests
- Growth chart
- Treatment
- Growth hormone
- Growth Hormone Deficiency
- Main diagnosis
- Anatomy and histology of pituitary gland
- Brain
- Forebrain
- Diencephalon
- Ventral: hypothalamus
- Pituitary gland
- Hypothalamic nuclei and
neuroendocrine cells
- Adenohypophysis
- Pars distalis
- Pars intermedia
- Pars tuberalis
- Pars distalis
- Neurohypophysis
- Pars nervosa
- Infundibular stem
- Median eminence
- Pars nervosa
- Hypothalamic nuclei and
neuroendocrine cells
- Pituitary gland
- Ventral: hypothalamus
- Diencephalon
- Forebrain
- Brain
- NORMAL growth rate
- Height
- Weight
- Height
- yasser was taken to the M&CH center (maternity
hospital) where they get so many services and
check the child health and normal growing
- Services:
- All pediatric services
- Emergency services
- and others....
- All pediatric services
- Services:
- Follow the patient up
- To increase compliance
- To adjust the doses
- To increase compliance
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