Central Nervous System Drugs

Antidepressants
1. eg. SSRIs, TCAs, RIMs, MAOIs
  1. use: depression
    1. MOA: ^ levels & activity of serotonin & adrenaline
      1. AE: weight gain, sedation, nausea
Antipsychotics
1. LIthium
  1. use: control manic & depressive states
    1. MOA: May reduce noadrenaline activity in synaptic cleft
      1. AE: vomitting, diarrhoea, nervousness
2. Benzodiazepines
  1. use: anxiety & panic disorders
    1. MOA: ^ inhibitory effect of GABA
      1. AE: CNS depression
Anticonvulsants
1. eg: ethosuximide
  1. use: Antiepileptic
    1. MOA: stabilizes the nerve membranes
      1. AE: GI upset, headache, sedation
Narcotic Analgesics
1. eg: morphine
  1. MOA: stop release of substance P, supressing pain messages
    1. AE: sedation, hypnosis
2. NSAIDs
  1. eg: Ibuprofen
    1. use: patients with athritic joints
      1. MOA: inhibits cyclooxgenase enzymes
        AE: nausea, vomitting, headache
3. Paracetamol
  1. eg: panadol
    1. use: mild to moderate pain
      1. MOA: acts as an analgesic & antipyretic
        AE: hepatotoxicity
General Anaesthetics
1. nitrous oxide
  1. Inhaled
2. propofol
  1. IV
3. MOA: alter movement of ions in nerve cells
  1. AE: decreased BP, respiratory depression
Local Anaesthetics
1. eg: lignocaine
  1. MOA: block pain transmission
    1. AE: overdose, allergic reactions

Resource summary

	Created by Samara Watts about 7 years ago