1 in 13 people have asthma. More common in children than
adults. More boys than girls have it. African Americans die at a
higher rate than any other ethnicity. More common in adult
women than adult men.
Pathophysiology
Bronchospasms cause the airways to narrow.
Capillaries in the airways leak, contributing to
secretions, causing edema and preventing full
clearance of mucus. Mucus secreting glands expand,
giving way to a thick mucus plug blocking the airway.
Epithelial peeling can cause airway impairment
allowing antigens to penetrate causing the airways to
become hyper responsive. Without treatment, airway
remodeling can occur, which allows for loss of lung
function and poor response to medical treatment.
After treatment, the airways will not go back to
normal.