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16998549
Breast Lump
Description
Mind Map on Breast Lump, created by Salma Moustafa on 25/02/2019.
Mind Map by
Salma Moustafa
, updated more than 1 year ago
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Created by
Salma Moustafa
over 5 years ago
176
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0
Resource summary
Breast Lump
Anatomy of the breast
functional unit
duct-lobular unit
lies on
serratis anterior
pectoralis major
external oblique
Development of the breast
prenatal
starts at day 35 gestation
formation of mammary line
6 months
breast framework
infant
areola pigmented
nipple projects from growth of underlying mesoderm
puberty till adulthood
TANNER STAGES
Breast Cancer
Genetics
Subtypes
Luminal A
ER+
SERMs
Luminal B
ER+ Her2+
Her 2+
ER -ve, Her 2+
trastuzumab
Basal like
ER-, HER2-
chemotherapy
Risk factors
BRCA-1 and BRCA-2
increased oestrogen exposure
age at first birth
early menarche, late menopause
obesity
non-invasive
ductal carcinoma in situ
malignant proliferation of ductal cells
doesn't cross BM
comedocarcinoma
central necrosis and calcification
paget disease
intraepithelial adenocarcinoma
eczematous lesion on nipple
invasive
ductal carcinoma
DCIS crosses BM
nipple retraction
skin dimpling
lobular carcinoma
single sheet of cells
decreased E-cadherin expression
medullary carcinoma
fleshy, cellular,lymphocytic infiltrate
inflammatory
lymphatic invasion and blockage
p'eau d'orange
screening
mammogram
Media attachments
Tdlu (binary/octet-stream)
Unknown (binary/octet-stream)
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