Used to release energy and
provide nutrients to build cells
Mineral ions and vitamins
Small amounts needed
for cells to function
Malnourishment is too
much or too little food
Metabolic Rate
Is affected by your amount of muscle, how much
exercise you do and some inherited factors
The rate at which chemical
reactions are carried out
Inherited factors such can affect
things such as cholesterol
Defence against diseases
Pathogens
Bacterium release toxins and some can invade
and destroy blood cells (Smaller than our cells)
Viruses take over a cell's DNA and cause cells to make toxins
and damage them in the process (Much smaller than bacteria)
Immune system
Ignaz Semmelweis discovered hand washing
prevented the spread of diseases in pregnant women
Vaccinations
A small amount of dead/inactive pathogen is injected - this causes
white blood cells to produce antibodies - if you are infected by the
pathogen later your body can react quickly so you don't become ill
Mutations
Epidemic - A widespread occurrence of an infectious
disease in a community at a particular time
Pandemic - (of a disease) prevalent
over a whole country or the world.
A new strain of pathogen is produced - antibodies
don't recognise it - new strains could spread rapidly
Antibiotic resistance
Mutations create antibiotic-resistant strains - antibiotics
kill regular bacteria but resistant bacteria survise and
reproduces - this must be treated with a new more
powerful antibiotic - with no new antibiotic it may spread
Antibiotics
Medicines used to kill BACTERIAL pathogens
e.g.penicillin
Certain bacteria can only be
killed by specific antobiotics
Nervous system
Receptors
Stimulus - Change
in surroundings
Nervous System - Detects stimuli
and coordinates a response
Response - Change in an organism's
behaviour due to a stimulus
Responses
Reflex actions are automatic and involve very few neurones
1.A receptor cell produces and electrical pulse because of a stimulus 2.The impulse passes along a
sensory neurone to the central nervous system 3.It goes to a relay neurone in the central nervous
system 4.it then passes to a motor neurone 5.Finally it passes to the effector e.g.the arm
Control in the human body
Internal conditions
Water content is lost: when we breathe out (Lungs),
when we sweat to cool down (Skin) and in urine (Kidneys)
Ion content is lost: when we sweat (Skin) and when we urinate (Kidneys)
Menstrual cycle
Hormones
FSH - Produced in Pituitary glands - Matures the egg - Stimulates the production of oestrogen
LH - Produced in the pituitary glands - Cause the release of an egg - Inhibits Oestrogen
Oestrogen - Produced in the ovaries - Builds up the womb lining -
Inhibits production of FSH and stimulates the production of LH
Birth control - Contain oestrogen or progesterone (reduces headaches for women) which
means no eggs mature so no eggs are ready to be released
Increasing fertility
IVF - Fertilisation outside of a woman's body
Fertility drugs - contain FSH and LH which
stimulate eggs to mature and be released
Control in plants
Phototropism - Growth in response to light
Gravitropism - Growth in response to gravity
Auxin (Plant growth hormone produced in the shoot or root tip) grows on the shaded
side of a stem to elongate the cells and cause the plant to bend towards the light
Auxin is used in weedkiller and essentially grows the plant
so big it cannot recieve the nutrients required and dies
Drugs
Chemicals which affect how the body works
Trials
1.In the laboratory: The drug is tested on cultures
of cells, cultures of tissues and then animals
2.Clinical trials stage 1: Very small dose is tested on a healthy volunteer
3.Clinical trials stage 2: A patient with the disease is given different
doses of the drug to find the optimum dose and if it works
Placebo - A substance that has no therapeutic
effect, used as a control in testing new drugs
Double blind trials - When neither the patient or doctor know if the
patient is receiving a placebo so the metal effect doesn't affect the results
Thalidomide - Developed as a sleeping pill - Used to control morning sickness in women -
Caused severe limb abnormalities in babies - Thalidomide is now used to treat leprocacy
Statins - Reduce the risk of cardiovascular
disease in people with high cholesterol
Recreational drugs
Cannabis - Usually burned and breathed in, can cause mental illnesses
Addiction - When the drug makes the person dependent on it and
when the drug is no longer taken withdrawal symtoms occur
Drugs in sport
Stimulants - increase the rate of bodily functions e.g. faster
heart rate so muscles receive oxygen and sugar faster
Anabolic steroids - stimulate muscle growth
Social effects - Can harm people around them, could relax people, right to freedom
Adaptations
Competition
Plants compete for light, space, water and nutrients
Animal compete for food, territory and mates for reproduction
Animals in the Arctic - Small surface area to reduce heat loss, white colour for
camouflage in snow, thick fur and fat to insulate and large feet to increase grip
Animals in Deserts - Large water stores to remain
hydrated, large surface area to lose heat quickly,
thick fur on top to insulate from sun's heat
Extremophiles
Live in high levels of salt
Live in high temperatures
Live in high pressures
Indicators
Bloodworms indicate polluted water
Mayfly larvae indicate unpolluted water
The colour of a lichen can indicate the pollution in the air
Energy in Biomass
Light energy from Sun - Energy captured by plants -
Photosynthesis occurs - Chemical energy is stored in cells
Biomass at each stage reduces due to respiration
Decay
Occurs when an organism has died, it returns materials to the enviroment
It is performed by microbes: Most active when warm, moist and high levels of oxygen
The carbon cycle
Genes
Genes control the characteristics of the body
Environment (e.g. scars) and genes
(e.g. eye colour) effect your variations
Half your genes are inherited from
your father and half from your mother
Reproduction
Plants
Asexual - No fusion of gametes (sex cells), only one
parent, no mixing of genetic information and all
offspring have the same genes as parent and each other
Animals
Sexual - Gamete from other fuses with gamete from father,
mixed genetic information from each parent and offspring have
different combinations of genes, so varying characteristics
Cloning
Tissue culture - A few plant cells are
taken and cultured into an identical plant
Embryo transplants - All offspring are identical
and are developed from a single embryo
Adult cell cloning
Genetic engineering
The transfer of a gene from one organism to another
so the organism receives the desired characteristics
The wanted gene is removed from a chromosome using enzymes
- the gene is inserted into the nucleus of a cell in the other
organism - the cell of the second organism now posses this gene
Issues
Economic - Is the cost worth it
Social - Are there benefits for society
Ethical - Is it morally right
Crops
Crops have been modified to: resist attack by insects
and resistance to herbicides so only weeds are killed
Herbicide resistant crops may transfer the
gene to weeds so weeds are no longer killable
Herbicide kills wild flowers so less food
for insects thus the whole food chain
Insecticide-resistant pests may develop
and become resistant to insecticide
Modified crops could harm human life
Evolution
Darwin's theory
Natural selection
Individuals have varying characteristics - Some variations are better suited to
certain environments - Individuals with more suitable variations survive and
reproduce - The next generation have the developed genes for the environment
Lamarck's Theory
Inheritance of characteristics
Environmental factor e.g. weight training - Causes certain
characteristics e.g. increased muscles size - These characteristics
are inherited by the offspring e.g. young have large muscles
Classification
Organisms are grouped as plant, animal or
micro-organism based on their charcteristics
All organisms developed from simple
life forms over 3 billion years ago
Evolutionary trees are used to show
relationships between organisms