Enzyme Inhibitors

Inhibitors: substances that reduce the reaction rate in an enzyme controlled reaction because they have some effect on the enzyme
Competitive inhibitors have a similar shape to the substrate
1. They can occupy the active site forming enzyme inhibitor complexes
Enzyme inhibition occurs whenever a inhibitor molecule is occupying an enzymes active site, a substrate molecule cannot enter so the rate of reaction slows down
Non-competitive inhibitors don't compete for a place in the active site
1. they attach to the enzyme molecule in a region away from the active site
  1. this attachment distorts the 3D structure, this leads to a change in shape of the active site
    1. this means the substrate no longer fits, so e/s complexes can't form and the rate of reaction decreases

Resource summary

	Created by imaumoh123 almost 10 years ago