Infective Endocarditis

Pathophysiology
1. Pre-existing endocardial damage
2. Previously normal heart
3. Microbiology
Incidence
1. > 60 years
2. underlying conditions
  1. Rheumatic heart disease
  2. Congenital heart disease
  3. other cardiac abnormality
    1. calcified aortic valve
    2. floppy mitral valve
Clinical features
1. Subacute
2. Acute
3. Post-operative
Investigations
1. Blood culture
2. Echocardiography
3. ESR, CRP, TWC
4. ECG
5. Chest X-ray
Management
Introduction
1. due to
  1. microbial infection of a heart valve
    1. native
    2. prosthetic
  2. the lining of a cardiac chamber or blood vessel
  3. a congenital anomaly
    1. septal defect
2. causative organism
  1. bacterium (usually)
  2. Rickettsia
  3. Chlamydia
  4. Fungus
Prevention
1. antibiotic prophylaxis no longer offered

Resource summary

	Created by DrAAR over 9 years ago