Colorectal carcinoma

Description

Mind Map on Colorectal carcinoma, created by gifted1 on 24/05/2015.
gifted1
Mind Map by gifted1, updated more than 1 year ago More Less
sherry_zaman
Created by sherry_zaman over 9 years ago
gifted1
Copied by gifted1 over 9 years ago
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Resource summary

Colorectal carcinoma
  1. polyps
    1. <1% chance of malignant transformation
      1. inherited polyposis
        1. familial adenomatous polyposis FAP
          1. Gardener's syndrome
            1. aka familial colorectal polyposis
              1. AD
              2. Turcot's syndrome
                1. rarediseases.info!
                  1. polyps->colorectal ca
                    1. brain tumours
                  2. Peutz-Jeghers (AD)
                    1. polyps and pigmentation
                    2. Cowden's disease
                      1. multiple hamartoma syndrome
                        1. skin 100%
                          1. thyroid 60%
                            1. ca
                            2. GIT
                              1. ca
                              2. breast ca
                                1. others
                              3. familial juvenile polyposis
                                1. hyperplastic polyposis
                                2. common
                                  1. colonic polypectomy
                                    1. hyperplastic 90%
                                      1. adenomas 10%
                                        1. tubular
                                          1. tubulovillous
                                            1. villous
                                            2. imaging
                                              1. CT colon
                                                1. colonoscopy
                                              2. common
                                                1. rectosigmoid 60%
                                                2. risk factors
                                                  1. history of adenoma
                                                    1. FH of adenoma
                                                      1. IBD
                                                        1. pelvic irradiation
                                                          1. low fibre, high fat diets
                                                            1. asbestos
                                                              1. hereditary non-polyposis colorectal cancer syndrome (Lynch syndrome)
                                                                1. +ve FH
                                                                  1. Lynch I
                                                                    1. Lynch II ass. with GU tract TCC
                                                                  2. Dukes staging
                                                                    1. A: mucosa 85% 5 yr survival
                                                                      1. B: muscularis 70% 5 yr survival
                                                                        1. C: LN 30% 5yr survival
                                                                          1. D: distant mets 5% 5yr survival
                                                                            1. liver
                                                                              1. lung
                                                                                1. adrenals
                                                                                  1. ovary
                                                                                    1. bone
                                                                                      1. brain
                                                                                        1. peritoneum
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