Integration of Metabolism

Description

Medicina Mind Map on Integration of Metabolism, created by Daniel Alejandro Gutiérrez Daza on 17/02/2021.
Daniel Alejandro Gutiérrez Daza
Mind Map by Daniel Alejandro Gutiérrez Daza, updated more than 1 year ago
Daniel Alejandro Gutiérrez Daza
Created by Daniel Alejandro Gutiérrez Daza almost 4 years ago
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Resource summary

Integration of Metabolism
  1. Metabolism is the coordinated activity of cells
    1. Objectives
      1. To get chemical energy
        1. Such as: ATP NADH NADPH FADH2
        2. Molecular conversion
          1. Molecules precursors
          2. Polymerize monomers into macromolecules
            1. Proteins Polysaccharides Nucleic Acids
            2. Synthesize and degrade specialized biomolecules
              1. Lipids Membrane Proteins Pigments
            3. Is the whole chemical transformation of an organism
              1. It takes its place through Metabolic Pathways
                1. Join in a dynamic steady state, it means that saves the Homeostasis
                  1. The products from a metabolic pathway (Metabolites), could be the reactive of another one.
                  2. Metabolic Pathways
                    1. Catabolic
                      1. Convergent Ramifications
                        1. Produce chemical energy
                        2. Glycolysis Glyconeogenesis
                          1. Pentose phosphate cycle Amino acid-oxidation & urea production
                            1. Oxidative Phosphorylation Fat Acids catabolism
                            2. Anabolic
                              1. Divergent Ramifications
                                1. Use chemical products as reactives
                                2. Biosynthesis of: Lipids Amino acids Nucleic acids
                                3. Anfibolic
                                  1. Cyclic
                                    1. Citric acid cycle Krebs cycle
                                  2. Related Organs
                                    1. Heart
                                      1. Fat acids oxidation Glucose Caption Glycolisis
                                      2. Adipose Tissue
                                        1. Fat acids synthesis Lipolysis
                                        2. Brain
                                          1. Ingestion of food
                                          2. Liver
                                            1. Synthesis of: Fat acids Cholesterol Glycogen
                                            2. Pancreas
                                              1. Insulin secretion
                                              2. Esqueletic Muscle
                                                1. Fat acids & Glycose caption Mitochondrial Biogenesis
                                              3. Metabolic Regulation
                                                1. Regulated by AMPK
                                                  1. Affected by: >AMP <ATP Exercise SNS Peptide hormones
                                                  2. Types of regulation
                                                    1. Internal
                                                      1. Intracellular subtract concentration Alosteric regulation
                                                      2. External
                                                        1. Immediately regulation
                                                          1. Growth Factors Hormones
                                                            1. Control Enzymatic activity
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