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297502
Glycogen Phosphorylase Structure (Without Phosphorylation)
Description
Year 2 Mind Map on Glycogen Phosphorylase Structure (Without Phosphorylation), created by gina_evans0312 on 23/10/2013.
No tags specified
cell signalling and cancer
glycogen
year 2
Mind Map by
gina_evans0312
, updated more than 1 year ago
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Created by
gina_evans0312
about 11 years ago
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Resource summary
Glycogen Phosphorylase Structure (Without Phosphorylation)
T Form
Inactive- Active site it buried within protein
Caused by
High ATP
High glucose-6-phosphate
Glucose (In the liver)
R Form
Active- Active site is acessable to glycogen
Caused by
AMP
Pi
Phosphorylation
Interface domain
Contains allosteric effector site
Where ATP/AMP binds
Active Site
Found in deep groove to prevent water entering
Entrance of water causes hydrolysis instead of phosphorylysis
Made of
Glycogen Storage
Interface
And C Terminus Domains
This deep groove is what causes the steric hinderence during cleavage
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