Cell Signaling

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Chapter 15: Cell Signaling
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Cell Signaling
  1. Cell Surface Receptor Proteins
    1. Enzyme Coupled Receptor
      1. G-Protein Coupled Receptor
        1. Intracellular Signaling Molecules
          1. Small Chemicals
            1. cAMP
              1. Ca2+
                1. "2nd Messengers"
                2. Proteins
                  1. Molecular Switches
                    1. Phosphorylation/Dephosphorylation
                      1. Tyrosine Kinases
                        1. "Kinase Cascades"
                          1. Serine/Threonine Kinases
                          2. GTP/GDP binding
                            1. GAPs+GEFs
                              1. Trimeric G-Proteins
                                1. Monomeric GTPases
                              2. Generate 2nd Messengers
                                1. Caspases
                              3. Ion-Channel Coupled Receptor
                                1. Nerve Cells
                              4. Types of Signal Molecules
                                1. Proteins
                                  1. Neurotransmitters
                                    1. Gases
                                      1. Fatty Acids
                                      2. Signaling Characteristics
                                        1. Scaffolding Proteins
                                          1. Differences in Responses
                                            1. Distance
                                              1. Long Distance
                                                1. Endocrine
                                                  1. Synaptic
                                                  2. Short Distance
                                                    1. Autocrine
                                                      1. Paracrine
                                                        1. Contact Dependent
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