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Parkinson's Disease

Physical Effects
1. The lack of dopamine impairs movement by decreasing a person's control over their body. These symptoms are known as Parkinsonian Motor Symptoms.
  1. Parkinsonian Motor Symptoms
    1. Muscular Rigidity
      1. The inability for the muscles to relax normally, causing pain
    2. Postural and gait impairment
      1. Causes unsteady movements and a stooped posture
    3. Bradykinesia
      1. Is the slowness of initiation of voluntary movement with progressive reduction in speed and amplitude of repetitive actions
    4. Rest Tremor
      1. Is most common in the hands and forearms. It appears when the limbs are relaxed and it disappears with active movements
Pathophysiological Cause
1. Causative factors of Parkinson's remain unknown. But Parkinson's is a neurodegenerative condition due to a deficiency of not only dopaminergic cells, but also cholinergic, noradrenergic, serotonergic, histaminergic and glutaminergic cells, accounting for the wide clinical spectrum motor and non-motor functions that are affected
  1. Non-motor features including cognitive impairment, depression, hallucinations, autonomic features and sleep problems are also affected by Parkinson's Disease
    1. A decrease in dopamine production leads to the impairment of motor function
  2. Cholinergic cells are responsible for the activation during both wakefulness and rapid eye movement sleep
Spiritual Effects
Social Effects
Cognitive Effects
2. Sleep Deprivation due to lack of cholinergic cells in the body as well as the uncomfortable and uncontrollable effects of rest tremors and the pain caused by muscular rigidity
  2. A sleepy fatigued person is accident prone, has poor memory, is judgement impaired and more likely to make mistakes, bad decisions and have a loss of motivation
Holistic Effects

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Parkinson's Disease

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	Created by Lara Acuavera about 8 years ago