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quase 4 anos atrás
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Questão | Responda |
Tc 99 | Synthesis: Generator Decay: Internal conversion Emit: Gamma photon Half life: 6 hr Energy: 140 |
I 123 | Synthesis: Cyclotron Decay: Electron capture Emit: Photon Half life: 13 hr Energy: 159 |
I 131 | Synthesis: Fission Decay: Beta minus Emit: Beta (some gamma) Half life: 8 days Energy: 364 |
Ga 67 | Synthesis: Cyclotron Decay: Electron capture Emit: Photon Half life: 78 hr Energy: 90, 190, 290, 390 |
In 111 | Synthesis: Cyclotron Decay: Electron capture Emit: Photon Half life: 67 hr Energy: 173, 247 |
Tl 201 | Synthesis: Cyclotron Decay: Electron capture Emit: Photon Half life: 73 hr Energy: 69, 81 Critical organ: kidneys |
Xe 133 | Synthesis: Fission Decay: Beta minus Emit: Gamma (some beta) Half life: 5.3 d Energy: 81 Critical organ: trachea |
C 11 | Synthesis: Cyclotron Decay: Annihilation Emit: Positron Half life: 20 min Energy: 512 |
N 13 | Synthesis: Cyclotron Decay: Annihilation Emit: Positron Half life: 10 min Energy: 512 |
O 15 | Synthesis: Cyclotron Decay: Annihilation Emit: Positron Half life: 2 min Energy: 512 |
F 18 | Synthesis: Cyclotron Decay: Annihilation. Election capture. Emit: Positron Half life: 110 min Energy: 512 |
Ru 82 | Synthesis: Generator Decay: Annihilation Emit: Positron Half life: 1 min Energy: 512 |
Radionuclide Purity | 0.15 uCi Mo per 1 mCi Tc Dose calibrator |
Radiochemical Purity | < 5% free Tc (some say < 10%) Thin layer chromatography |
Chemical Purity | < 10 ug Al per 1 mL Tc Paper colorimetry (pH paper) |
Nuclear Spills Major if > x | 1 mCi - I 131 10 mCi - Ga 67, In 111, I 123 100 mCi Tc 99, Tl 201 |
MEN 1 | Pituitary adenoma Pancreatic islet cell Parathyroid adenoma/carcinoma |
Men IIa | Pheochromocytoma Medullary thyroid cancer Parathyroid hyperplasia |
Men IIb | Pheochromocytoma Medullary thyroid cancer Marfanoid habitus Ganglioneuromas (mucosal) |
VHL | Renal cell carcinoma Angiomyolipoma Pheochromocytoma Pancreatic cysts and cystic tumors Liver cysts Hemangioblastoma |
Tuberous Sclerosis | Cortical tubers Subependymal nodules Subependymal giant cell astrocytomas Angiomyolipoma Renal cell carcinoma Lymphangioleiomyomatosis Cardiac rhabdomyomas |
NF 1 | Plexiform neurofibroma Optic nerve glioma Sphenoid wing dysplasia |
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F18 (binary/octet-stream)
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NaF 18 Sharp bones |
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Fdg (binary/octet-stream)
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FDG |
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Ga67 (binary/octet-stream)
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Ga 67 Lacrimal glands Fuzzy PET |
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Hdp (binary/octet-stream)
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Tc HDP/MDP Fuzzy bones |
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I23 (binary/octet-stream)
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I 123 Sharp thyroid Glands, GI, GU, nasopharynx |
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I31 (binary/octet-stream)
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I 131 Fuzzy thyroid Glands, oral cavity, liver, bowel, bladder |
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Mibg (binary/octet-stream)
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MIBG Myocardium, liver, salivary gland, thyroid Bone = abnormal |
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Mibi (binary/octet-stream)
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Tc Sestamibi Glands, thyroid, heart, liver Critical organ: gallbladder |
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Oct (binary/octet-stream)
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Octreoscan In 111 Liver, spleen, kidneys |
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Sco (binary/octet-stream)
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Tc sulfur colloid Liver > spleen Critical organ: liver FNH +; adenoma -; hemangioma - |
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Tc (binary/octet-stream)
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Tc pertechnetate Glands, thyroid, stomach, breast Critical organ: colon |
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Wbc (binary/octet-stream)
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In 111 WBC Spleen > liver Critical organ: spleen |
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Psma (binary/octet-stream)
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PSMA F 18 Lacrimal glands, salivary, liver, spleen, kidneys, bowel |
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Dota (binary/octet-stream)
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DOTA Ga 68 Pituitary, uncinate, liver, spleen, GU |
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Dtpa (binary/octet-stream)
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DTPA In 111 Normal |
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Hmpao (binary/octet-stream)
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HMPAO Tc 99 |
FDG | |
DTPA In 111 Brain death | |
HMPAO Tc 99 Interictal | |
DTPA In 111 Cisternogram Normal | |
DTPA In 111 Cisternogram NPH (in vents) | |
FDG Normal | |
Florbetapir F 18 Normal white matter uptake No gray matter uptake to suggest plaque | |
DAT scan - Ioflupane I 123 Normal comma shaped caudate Absence = Parkinson | |
Florbetapir F 18 Alzheimer Loss of gray white Abnormal uptake in gray matter | |
FDG F 18 Alzheimer Posterior cingulate Temporo-parietal Spares motor strip Spares visual cortex | |
FDG F 18 Pick's Frontotemporal | |
FDG F 18 Lewy Body Does not spare occipital | |
Uniformity Intrinsic (collimator off) Extrinsic (collimator on) Co 57 Daily | |
Spatial resolution & Linearity Weekly | |
Energy spectrum Daily or automatic with each use | |
Jaszczak phantom Spatial resolution & Linearity Weekly | |
Energy resolution & linearity Annually | |
Center of rotation test Monthly | |
MQSA: - Education hours - CME - CME for new modality - Case volume as trainee - Case volume in practice | Education - 60 hours CME - 15 credits in 3 years New modality - 8 credits Cases - 240 w/in 6 months, 2 yr prior to graduating Continue in practice - 960 in 2 yrs |
MQSA Audit Frequency | 12 month |
MQSA QC: Processor | Daily |
MQSA: Darkroom cleanliness | Daily |
MQSA QC: Phantom evaluation | Weekly |
MQSA QC: Viewbox conditions | Weekly |
MQSA QC: Repeat analysis | Quarterly |
MQSA QC: Screen film contact | Semi-annually |
MQSA QC: Darkroom fog | Semi-annually |
MQSA QC: Compression test | Semi-annually |
Breast QC Density difference & background density Background must be < 0.2 OD of baseline Density diff must be < 0.05 OD of baseline | |
MQSA phantom, how many: - Fibers - Speck groups - Masses | 2018 MQSA says: >= 2 fibers >= 3 speck groups >= 2 masses |
Spatial resolution test (breast) > 11 or 13 line pairs per mm | |
MQSA Audit: Cancers detected (per 1,000) | > 2.5 |
MQSA Audit: Recall rate | 5-12% |
MQSA Audit. Define: - PPV1 - PPV2 - PPV3 | - PPV1: #cancer/#recall - PPV2: #cancer/#biopsies recommended - PPV3: #cancer/#biopsies performed |
MQSA Audit: PPV1 | 3-8% PPV1 = # cancer / # recalls |
MQSA Audit: PPV2 | Screening: 15-40% Palpable lump: 25-50% PPV2 = #cancer / #biopsies recommended |
MQSA Audit: PPV3 | Screening: 20-45% Palpable lump: 30-55% PPV3 = #cancer / #biopsies performed |
MQSA: Notify pts of results in ___ days. If suspicious, then ___ days. | 30 days. 5 days. |
MQSA: Mammograms must be retained for how long? | 5 years (default) OR 10 years if no priors |
Occupational Max Radiation Dose: Whole body | 50 mSv = 5,000 mrem |
Occupational Max Radiation Dose: Eye lens | 150 mSv = 15,000 mrem |
Occupational Max Radiation Dose: Extremity | 500 mSv = 50,000 mrem |
Occupational Max Radiation Dose: Pregnant | 5 mSv from declaration date |
Max Radiation Dose: Member of public | 1 mSv = 100 mrem per year |
Radiation Deterministic Effect: Transient erythema | 3-6 Gy |
Radiation Deterministic Effect: Epilation (hair loss) | 4 Gy |
Radiation Deterministic Effect: Cataract | 0.5 Gy (new number) 5 Gy (old literature) |
Radiation Deterministic Effect: Sterility | 3.5 Gy (male), 2.5 Gy (female) |
Radiation Deterministic Effect: Bone marrow suppression | 0.5 Gy |
Radiation Deterministic Effect: Cognitive effects | 1-2 Gy (adult), 0.1-0.2 Gy (infant) |
Radiation Deterministic Effect: Lethal dose | 5 Gy |
Radiation Stochastic Effect: Excess relative risk of cancer (% per Sv) | 4-5% per Sv in adults 5.5-6.0% per Sv all comers |
Radiation Stochastic Effect: 1) Fetus threshold 2) Effect by weeks | 1) > 100 m Gy 2) - weeks 0-2 = death - weeks 3-8 = organogenesis problems - weeks 8 - 15= cognitive problems |
I 123 Thyroid 24 hr Uptake: - Normal range - Graves range | Normal 10-30% Graves 40-70% |
I 131 Dose: Graves Multinodular goiter Post-surgical thyroid remnant Metastasis | Graves 10 - 15 mCi Goiter 20 - 30 mCi Thyroid remnant 75 - 150 mCi Metastasis 200 mCi |
After I 131, send patient home when: | - If dose < 33 mCi - Pt < 7 mrem/hr at 1 meter - Dose to family < 500 mrem |
VQ perfusion scan - Number beads - Size beads - Decrease dose for these populations | Normal: 200,000-600,000 beads 100,000-200,000 if infant, R->L shunt, pregnant, or pulm HTN Size 30 - 50 um |
Tc 99 RBC scan Sensitivity 0.2 mL/min (0.04 in some studies) Critical organ: colon & heart | |
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Meckel (binary/octet-stream)
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Meckel Scan Tc pertechnetate Critical organ: thyroid |
HIDA (DISIDA) CCK (sincalide) dose | 0.02 mcg/kg over 15 - 60 min |
HIDA (DISIDA) morphine dose | 0.04 mg/kg (over 3 min) |
HIDA (DISIDA) phenobarbital dose | 5 mg/kg/day for 5 days |
Gallbladder EF < ___ = chronic cholecystitis / biliary dyskinesia | 35% |
Gastric emptying: Delayed if ___ residual at 1 hr or ____ at 4 hr | 90%, 10% |
Diuretic renography. Lasix dose? | 40 mg |
Renograph for obstruction. Normal half time? Abnormal half time? | < 10 min = normal 10 - 20 min = indeterminate > 20 min = obstruction (somewhat related, normal time to peak is 3-5 min) |
Radiation dose limit for unrestricted area | 2 mrem/hr = 0.02 mSv/hr |
Surface dose limit? 1 meter? | I - surface 0.5 mrem/hr (5 uSv) II - surface 50 mrem/hr (0.5 mSv) - 1 meter 10 mrem/hr (0.1 mSv) III - surface 200 mrem/hr (2 mSv) - 1 meter 10 mrem/hr (0.1 mSv) |
Fission produced radioisotopes | I 131, Xe 133, (Mo 99) |
Cyclotron produced radioisotopes | I 123, F 18, Ga 67, In 111, Tl 201, Mo 99 |
Nuclear gastroesophageal reflux study threshold | > 4% is abnormal Tc sulfur colloid study |
Mammogram anode/target k-edge: - Molybdenum - Rhodium - Tungsten (Iodine, silver, and barium for fun) | Molybdenum 20 keV Rhodium 23 Tungsten 70 (Iodine 33, Silver 25, Barium 37) |
Fluoro: leakage from x-ray tube housing must be less than... | 1 mGy/h at 1 m |
Sentinel event = _____ unintended cumulative dose (according to Joint Commission) | 15 Gy = root cause analysis & Joint Commission inspector visit |
Fluoro: max entrance air kerma (according to FDA) | 100 mGy/min |
Gamma camera QC tests and timing | - Extrinsic uniformity (daily) - Photopeaking (daily) - Intrinsic uniformity (weekly) - Bar phantom (weekly) - Center of rotation (monthly) - Jascszak phantom (quarterly) |
Dose calibrator tests and timing | CLAG - Constancy (daily) - Linearity (quarterly) - Accuracy (annually) - Geometry (at installation/repair) |
K space (contrast vs sharpness): - Central = - Peripheral = | Central = contrast Peripheral = sharpness |
Radiation deterministic effects: - Erythema - Epilation - Desquamation - Atrophy/necrosis | - Erythema 2-5 Gy - Epilation 5-10 Gy - Desquamation 10-15 Gy - Atrophy/necrosis >15 Gy |
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