Criado por whospiltmybeer13
aproximadamente 9 anos atrás
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Questão | Responda |
Psychopharmacology | the study of effects of drugs on the nervous system and on behavior |
Drug effect | the changes a drug produces in an animal's physiological processes and behavior |
Site of action | A location at which molecules of drugs interact with molecules located on or in cells of the body, thus affecting some biochemical processes of these cells |
Pharmacokinetics | the process by which drugs are absorbed, distributed within the body, metabolized and excreted |
Intravenous (IV) injection | injection of a substance directly into a vein |
Intraperitoneal (IP) injection | Injection of a substance into the peritoneal cavity - the space that surrounds the stomach, intestines, liver, and other abdominal organs |
Intramuscular (IM) injection | injection of a substance into a muscle |
Subcutaneous (SC) injection | injection of a substance into the space beneath the skin |
oral administration | administration of a substance into the mouth so that it is swallowed |
Sublingual administration | administration of a substance by placing it beneath the tounge |
Intrarectal administration | administration of a substance into the rectum |
Inhalation | administration of a vaporous substance into the lungs |
Topical administration | administration of a substance directly onto the skin or mucous membrane |
Intracerebral administration | administration of a substance directly into the brain |
Intracerebroventricular (ICV) administration | administration of a substance into one of the cerebral ventricles |
Dose-response curve | a graph of the magnitude of an effect of a drug as a function of the amount of drug administered |
Therapeutic index | the ratio between the dose that produces the desired effect in 50% of the animals and the dose that produces toxic effects in 50% of the animals |
Affinity | the readiness with which two molecules join together |
Tolerance | A decrease in the effectiveness of a drug that is administered repeatedly |
Sensitization | an increase in the effectiveness of a drug that is administered repeatedly |
Withdrawal symptom | the appearance of symptoms opposite to those produced by a drug when the drug is administered repeatedly and then suddenly no longer taken |
Placebo | an insert substance that is given to an organism in lieu of a physiologically active drug; used experimentally to control for the effects of mere administration of a drug |
Antagonist | a drug that opposes or inhibits the effects of a particular neurotransmitter on the post-synaptic cell |
Agonist | a drug that facilitates the effects of a particular neurotransmitter on the post-synaptic cell |
Direct agonist | a drug that binds with and activates a receptor |
Receptor blocker | a drug that binds with a receptor but does not activate it; prevents the natural ligand from binding with the receptor. |
Direct antagonist | a synonym for receptor blocker |
Noncompetitive binding | binding of a drug to a site on a receptor; does not interfere with the binding site for the principle ligand |
Indirect antagonist | a drug that attaches to a binding site on a receptor and interferes with the action of the receptor; does not interfere with the binding site for the principle ligand |
Indirect agonist | a drug that attaches to a binding site on a receptor and facilitates the action of the receptor; does not interfere with the binding site for the principle ligand |
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