Connective Tissue

Descrição

Univeristy Histology Mapa Mental sobre Connective Tissue, criado por Celina Gupta em 27-11-2018.
Celina Gupta
Mapa Mental por Celina Gupta, atualizado more than 1 year ago
Celina Gupta
Criado por Celina Gupta quase 6 anos atrás
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Resumo de Recurso

Connective Tissue
  1. Fibrillogenesis
    1. 1. Type 5 and 11 form a fibrillar core
      1. 2. Type 1 col. molecules are deposited and polymerised on the core
        1. 3. Small amounts of Type 2 and 3 col. molecules are incorporated into T1 col. fibrils
    2. Elastic fibres
      1. Accumulated EFs= yellow
        1. Stain: Orcein (red-brown)
          1. Loose CT Proper
          2. Reticular fibres
            1. Type III Col. fibrils embedded in glycoCHON matrix
              1. Supporting network for cells in liver, glands and muscle tissue
                1. Stain: Ag impregnation, PAS run
                  1. Reticular tissues- creates storm of hemopoietic organs
                  2. Ground Substance
                    1. GAGS
                      1. Hyaluronic acid
                        1. Sulphated GAGs
                          1. Proteoglycans
                            1. Multiadhesive glycoproteins
                            2. Cartilage
                              1. Hyaline
                                1. Elastic
                                  1. Fibrocartilage
                                  2. Components
                                    1. GAG
                                      1. Decorin
                                        1. Perlecan
                                          1. Syndecan
                                          2. Proper CT Cells
                                            1. Dense collagen- CT Proper
                                              1. Aniline blue
                                                1. T1 collagen form thick bundles in reticular, skin, sclera and joint fascia
                                              2. Collagen
                                                1. Staining: HE= Pink, Trichromes= named colour
                                                  1. T1: form fibres
                                                    1. T2: cartilage
                                                      1. T3: reticular fibre
                                                        1. Biosynthesis of T1

                                                          Anotações:

                                                          • 1. Collagen alpha chains are syn. in RER 2. Post-translational modification take place within the RER cisternae  3. Triple helix is formed with the help of hsp47 4. Intrachain and interchain H and S bonds form --> shape is influenced  5. Procollagen molecules --> Golgi --> Secretory vesicles --> Exocytosis 6. Fibrillogensis occurs
                                                          1. Fibrillar: 1,2,3,5,9
                                                            1. Hexagon forming: 8, 10
                                                              1. Basement membrane: 4,6,7
                                                                1. Degradation:
                                                                  1. Proteoglycan
                                                                    1. Phagocytotic
                                                                  2. Dense Regular CT
                                                                    1. Parallel bundles of collagen fibres
                                                                    2. Specialised types of CT
                                                                      1. Elastic: Orcein (red-brown)
                                                                        1. Reticular: AgNO3 (black)
                                                                          1. White adipose tissue
                                                                        2. Collagen fibres
                                                                          1. Closely packed Type 1
                                                                            1. Stains with acid dyes: eosin, aniline blue
                                                                              1. Found in: CT Proper, fibrocartilage

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