Carboxylic Acid Derivatives

Descrição

Some derivatives of carboxylic acids - Acyl Chloride and Acid Anhydride
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Resumo de Recurso

Carboxylic Acid Derivatives
  1. OH replaced by other groups
    1. Acyl Chloride
      1. Very reactive
        1. + alcohol/phenols = Esters at rtp.
          1. + amines = amides at rtp
            1. + water = carboxylic acid + HCl
              1. acylating agent
              2. Acid Anhydride
                1. more reactive than COOH
                  1. + phenols = esters
                    1. less than acyl chlorides
                    2. vigorous ethanoylating agent
                      1. made by eliminating water from COOH molecules
                        1. used instead of acyl chlorides
                          1. less dangerous
                            1. less expensive
                              1. less toxic
                              2. acylating agent

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