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Sickle Cell Anemia

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(Biology Exam 2) Mapa Mental sobre Sickle Cell Anemia, criado por izzy5605 em 22-10-2013.
izzy5605
Mapa Mental por izzy5605, atualizado more than 1 year ago
izzy5605
Criado por izzy5605 mais de 11 anos atrás
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Resumo de Recurso

Sickle Cell Anemia
  1. change in one nucleotide
    1. changes entire amino acid sequence
      1. changes structure of protein
        1. changes shape of red blood cell (sickle shape)
          1. protein misfolding
            1. some hydrophobic amino acids could be displayed on surface
              1. changes cell function
      2. inherited
        1. protein aggregation
          1. because of misfolding they clump together
          2. malaria
            1. one sickle cell mutation and one non mutated gene
              1. resistant to malaria

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