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Glycogen Phosphorylase Structure (Without Phosphorylation)

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Year 2 Mapa Mental sobre Glycogen Phosphorylase Structure (Without Phosphorylation), criado por gina_evans0312 em 23-10-2013.
gina_evans0312
Mapa Mental por gina_evans0312, atualizado more than 1 year ago
gina_evans0312
Criado por gina_evans0312 aproximadamente 11 anos atrás
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Resumo de Recurso

Glycogen Phosphorylase Structure (Without Phosphorylation)
  1. T Form
    1. Inactive- Active site it buried within protein
      1. Caused by
        1. High ATP
          1. High glucose-6-phosphate
            1. Glucose (In the liver)
        2. R Form
          1. Active- Active site is acessable to glycogen
            1. Caused by
              1. AMP
                1. Pi
                  1. Phosphorylation
              2. Interface domain
                1. Contains allosteric effector site
                  1. Where ATP/AMP binds
                2. Active Site
                  1. Found in deep groove to prevent water entering
                    1. Entrance of water causes hydrolysis instead of phosphorylysis
                      1. Made of
                        1. Glycogen Storage
                          1. Interface
                            1. And C Terminus Domains
                            2. This deep groove is what causes the steric hinderence during cleavage

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