347990
Systemic Lupus
Erythematosus
- disturbed immune
regulation, overproduction
of autoantibodies (B & T
cells)
- CM's - can affect any body system,
arthritis/arthralgias common, butterfly rash on
nose & cheeks (most common),
papulosquamous/annular polycyclic lesions
(subacute), papules/plaques & scaling w/
scarring & pigmentation changes, pericarditis,
subtle behavior & intelligence changes
- Corticosteroids (most
important) - used topically,
low/high oral doses, IV;
antimalarials, NSAID's,
immunosuppressives for
severe forms
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