4178274
Descrição
Mapa Mental por Judith Yan, atualizado more than 1 year ago
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Criado por Judith Yan
mais de 9 anos atrás
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Glycan Structure & Complexity
- related fields
- genomics
- gene sequence
- gene sequence
- proteomics
- proteins
- post-translational modification
- post-translational modification
- peptides
- proteins
- glycomics
- cell glycans
- cell glycans
- genomics
- Locations in the cell?
- membrane-associated glycoforms
- classifications
- glycolipids
- glycan functions in the ectodomain
- linkage
- glucose -- ceramide
- glucose -- ceramide
- glycan functions in the ectodomain
- glycoproteins
- polypeptide
- ectodomain
- cytoplasmic domain
- ectodomain
- covalent linkage
- N - asp
- O - Ser/Thr
- N - asp
- glycan functions in the ectodomain
- polypeptide
- proteoglycans
- long glycan part
- lots of SO4-
- prevents collapsing
- prevents collapsing
- examples
- syndecans
- glypicans
- CD44
- syndecans
- in extracellular matrix:
- aggrecan/versican
- "test-tube brush"
- "test-tube brush"
- glycosaminoglycans
- hyaluronan
- DRU + tetrasaccharide - ser
- hyaluronan
- aggrecan/versican
- long glycan part
- glycolipids
- lectin-saccharide interactions
- cell-cell interactions
- recognition
- by viral proteins
- cell-cell
- by bacteria
- by viral proteins
- adhesion
- epithelial layer formation
- epithelial layer formation
- binding of toxins...?
- recognition
- strength
- weaker than antigen-antibody
- weaker than antigen-antibody
- functions
- fertilization
- immunity
- infection
- cancer
- fertilization
- cell-cell interactions
- synthesis
- quality-control
- addition of glycan
- Golgi apparatus
- Golgi apparatus
- sorting
- ER
- ER
- addition of glycan
- extocytosis
- quality-control
- examples
- blood group glycoprotein
- tetrasaccharide
- has fifth sugar: A/B
- no fifth sugar: O
- has fifth sugar: A/B
- tetrasaccharide
- blood group glycoprotein
- classifications
- intracellular
- storage glycoforms
- starch (plants)
- amylopectin
- amylose
- a-1,4 linear
- a-1,4 linear
- a-1,4 / 1,6
- amylose
- amylopectin
- glycogen (animals)
- a-1,4 / 1,6
- many nonreducing ends
- digestion
- intracellular
- glycogen phosphorylase
- releases glc-1-phosphate
- releases glc-1-phosphate
- debranching enzymes
- glycogen phosphorylase
- extracellular
- alpha amylase
- random attacks alpha-1,4
- random attacks alpha-1,4
- alpha amylase
- intracellular
- a-1,4 / 1,6
- insoluble
- starch (plants)
- storage glycoforms
- membrane-associated glycoforms
- glucose metabolism
- glucose from diet
- amylase action
- gut lumen
- intestinal absorption
- hepatic portal vein
- hepatocytes
- glycolysis
- ATP
- ATP
- glycogenesis
- glycogen
- glycogen
- glycolysis
- hepatocytes
- hepatic portal vein
- intestinal absorption
- gut lumen
- amylase action
- glycogen from liver/myocyte
- glycogen phosphorylase
- glc-1-phosphate
- glc-6-phosphate
- glycolysis
- ...
- ...
- glycolysis
- glc-6-phosphate
- glc-1-phosphate
- glycogen phosphorylase
- glucose from diet
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