Drug Metabolism

Descrição

Notes from Doctors in Training
snlogel
Mapa Mental por snlogel, atualizado more than 1 year ago
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Criado por snlogel quase 11 anos atrás
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Resumo de Recurso

Drug Metabolism
  1. Phase I
    1. Reactions
      1. Reduction
        1. Oxidation
          1. Hydrolysis
          2. Metabolites
            1. Slightly polar
              1. Water soluble
                1. Active
              2. Phase II
                1. Reactions
                  1. Acetylation
                    1. Methylation
                      1. Sulfation
                        1. Glucuronidation
                        2. Metabolites
                          1. Very polar
                            1. Inactive
                          2. Disulfiram-like reaction
                            1. Metronidazole
                              1. Certain cephalosporins
                                1. Procarbazine
                                  1. 1st generation sulfonylureas
                                  2. Zero order kinetics
                                    1. Phenytoin
                                      1. Ethanol
                                        1. Aspirin
                                        2. TCAs
                                          1. Imipramine
                                            1. Clomipramine
                                              1. Amitriptyline
                                                1. Nortriptyline

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