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5214099
Innate Immune Response
Descrição
Innate Immune Response
Sem etiquetas
microbiology
2nd
semester
Mapa Mental por
Harisson Kueh
, atualizado more than 1 year ago
Mais
Menos
Criado por
Harisson Kueh
mais de 8 anos atrás
18
0
0
Resumo de Recurso
Innate Immune Response
non-specific
immune components preformed
response magnitude
similar during 1st and subsequent encounters
No memory is stored
1st lines of Defence
Physical barrier
saliva
antibacterial enzyme
mucus linings
traps dirt and microbes
Chemical barrier
skin
prevent entry of phatogents
tears
antibacterial enzyme
"good" gut bacteria
stop other harmful bacteria that taking over
2nd lines of defence
fever
increase temperature above 37
change settings of hypothalamus
initiated by pyrogens
benefits
reduced iron availability
Inhibition of microbial multiplication
increase metabolic reactions
inflammation
redness
heat
pain
oedema
stages of inflammation
tissue injury
release of chemical signals such as histamine
dilation and increased leakiness of local blood vessels
migration of phagocytes to the area
phagocytes
tissue heals
release of cytokines
vasodilation
phagocytosis
macrophages
neutrophils
posses lysosome
Antimicrobial proteins
complement system
interferons
iron-binding protein
Antimicrobial peptides
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