Nucleic Acids

Anotações:

• biopolymers made of nucleotides.

1. What is DNA/RNA Made of?
   1. 2. Nucleobase
      1. Purines
         1. Adenine (A) Guanine (G)
         2. Adenine (A) Guanine (G)
      2. Pyrimidines
         1. cytosine (C) Uracil (U)
         2. cytosine (C) Thymine (T)
   2. 3. Nucleotides
      1. Product of phospho group at 5' carbon (TP-triphosphate) (DP-diphosphate)
      2. Formula: Nuc-side + d/ + mono/di/tri d--deoxy DP--diphosphate TP--triphosphate
         1. dAMP dADP dATP dGMP dGDP dGTP dCMP dCDP dTMP dTDP dTTP
         2. AMP ADP ATP GMP GDP GTP CMP CDP CTP UMP UDP UTP
   3. 1. 5 carbon sugar
   4. +
      1. Nucleoside-- combination of a nucleobase and pentose
         1. DO-Adenosine, DO-guanosine, DO-cytidine, DO-thymidine
         2. Adenosine Guanosine Cytidine Uridine
2. Cyclic Nucleotide Derivatives
3. DNA
   1. DNA vs. RNA
   2. Circular vs Linear DNA
   3. DNA Superstructure
4. RNA
   1. RNA
      1. mRNA
      2. tRNA
      3. rRNA
      4. snRNA and scRNA