1807NRS Safe Administration of Medications 1

Question

Pharmacokinetics is:

Answer 1

The study of biological and therapeutic effects of drugs

Answer 2

The study of absorption, distribution, metabolism and excretion of drugs

Answer 3

The study of mechanisms of drug action

Answer 4

The study of methods of new drug development

Answer 5

Complications of drug therapy

Answer 6

Drug biotransformation in the organism

Answer 7

Influence of drugs on metabolism processes

Answer 8

Influence of drugs on genes

Answer 9

Pharmacological effects of drugs

Answer 10

Unwanted effects of drugs

Answer 11

Chemical structure of a medicinal agent

Answer 12

Distribution of drugs in the organism

Answer 13

Active transport (carrier-mediated diffusion)

Answer 14

Filtration (aqueous diffusion)

Answer 15

Endocytosis and exocytosis

Answer 16

Passive diffusion (lipid diffusion)

Answer 17

Lipid-soluble

Answer 18

Non-ionized substances

Answer 19

Hydrophobic substances

Answer 20

Hydrophilic substances

Answer 21

Low ability to penetrate through the cell membrane lipids

Answer 22

Penetrate through membranes by means of endocytosis

Answer 23

Easy permeation through the blood-brain barrier

Answer 24

High reabsorption in renal tubules

Answer 25

Transport of drugs trough a membrane by means of diffusion

Answer 26

Transport without energy consumption

Answer 27

Engulf of drug by a cell membrane with a new vesicle formation

Answer 28

Transport against concentration gradient

Answer 29

Plasma protein binding degree of substance

Answer 30

Permeability through the brain-blood barrier

Answer 31

Fraction of an uncharged drug reaching the systemic circulation following any route administration

Answer 32

Amount of a substance in urine relative to the initial doze

Answer 33

Rheological parameters of blood

Answer 34

Amount of a substance obtained orally and quantity of intakes

Answer 35

Extent of absorption and hepatic first-pass effect

Answer 36

Glomerular filtration rate

Answer 37

Transdermal

Answer 38

Intraduodenal

Answer 39

Sublingual

Answer 40

Intravenous

Answer 41

Intramuscular

Answer 42

Fast onset of effect

Answer 43

Absorption depends on GI tract secretion and motor function

Answer 44

A drug reaches the blood passing the liver

Answer 45

The sterilisation of medicinal forms is obligatory

Answer 46

A drug has a pretty fast absorption

Answer 47

A drug is exposed to gastric secretion

Answer 48

A drug is exposed more prominent liver metabolism

Answer 49

A drug can be administrated in a variety of doses

Answer 50

Sublingual

Answer 51

Inhalation

Answer 52

Cannot be used with unconsciousness patients

Answer 53

Generally results in a less accurate dosage than oral administration

Answer 54

Usually produces a more rapid response than oral administration

Answer 55

Is too slow for emergency use

Answer 56

Only water solutions can be injected

Answer 57

Oily solutions can be injected

Answer 58

Opportunity of hypertonic solution injections

Answer 59

The action develops slower, than at oral administration

Answer 60

Intravenous administration provides a rapid response

Answer 61

Intramuscular administration requires a sterile technique

Answer 62

Inhalation provides slow access to the general circulation

Answer 63

Subcutaneous administration may cause local irritation

Answer 64

Renal tubules

Answer 65

Cell membranes

Answer 66

Capillary walls

Answer 67

High lipid solubility of a drug

Answer 68

Meningitis

Answer 69

Absence of pores in the brain capillary endothelium

Answer 70

High endocytosis degree in a brain capillary

Answer 71

Single to a daily dose of an administrated drug

Answer 72

An administrated dose to a body weight

Answer 73

An uncharged drug reaching the systemic circulation

Answer 74

The amount of a drug in the body to the concentration of a drug in plasma

Answer 75

Concentration of a substance in plasma

Answer 76

Concentration of substance in urine

Answer 77

Therapeutical width of drug action

Answer 78

A daily dose of drug

Answer 79

Accumulation of substances in a fat tissue

Answer 80

Binding of substances with plasma proteins

Answer 81

Accumulation of substances in a tissue

Answer 82

Process of physicochemical and biochemical alteration of a drug in the body

Answer 83

Less ionized

Answer 84

More pharmacologically active

Answer 85

More lipid soluble

Answer 86

Less lipid soluble

Answer 87

Lipid soluble

Answer 88

Water soluble

Answer 89

Low molecular weight

Answer 90

High molecular weight

Answer 91

Microsomal oxidation always results in inactivation of a compound

Answer 92

Microsomal oxidation results in a decrease of compound toxicity

Answer 93

Microsomal oxidation results in an increase of ionization and water solubility of a drug

Answer 94

Microsomal oxidation results in an increase of lipid solubility of a drug thus its excretion from the organism is facilitated

Answer 95

Require the dose increase of some drugs

Answer 96

Require the dose decrease of some drugs

Answer 97

Prolong the duration of the action of a drug

Answer 98

Intensify the unwanted reaction of a drug

Answer 99

Acetylation and methylation of substances

Answer 100

Transformation of substances due to oxidation, reduction or hydrolysis

Answer 101

Glucuronide formation

Answer 102

Binding to plasma proteins

Answer 103

Faster urinary excretion

Answer 104

Slower urinary excretion

Answer 105

Easier distribution in organism

Answer 106

Higher binding to membranes

Answer 107

Process of drug reduction by special enzymes

Answer 108

Process of drug oxidation by special oxidases

Answer 109

Coupling of a drug with an endogenous substrate

Answer 110

Solubilization in lipids

Answer 111

Acetylation

Answer 112

Hydrolysis

Answer 113

Remained unchanged

Answer 114

Changed insignificantly

Answer 115

Change the amount of a drug in plasma by half during elimination

Answer 116

Metabolize a half of an introduced drug into the active metabolite

Answer 117

Absorb a half of an introduced drug

Answer 118

Bind a half of an introduced drug to plasma proteins

Answer 119

Biotransformation

Answer 120

Time of drug absorption

Answer 121

Concentration of a drug in plasma

Answer 122

Rate of drug elimination

Answer 123

Rate of renal tubular reabsorption

Answer 124

Clearance speed of some volume of blood from substance

Answer 125

Time required to decrease the amount of drug in plasma by one-half

Answer 126

Clearance of an organism from a xenobiotic

Answer 127

Only the concentration of substances in plasma

Answer 128

Only the elimination rate constant

Answer 129

Volume of distribution, half life and elimination rate constant

Answer 130

Bioavailability and half life

	Criado por Kathleen Jackson aproximadamente 7 anos atrás

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1807NRS Safe Administration of Medications 1

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