Questão 1
Questão
What is characteristic of the Paget's disease?
Responda
-
increased osteoblast and osteoclast activity
-
"bone pain" generally in one area, commonly pelvis and spine
-
structurally disorganized bone matrix with both excessive bone mass and bone resorption
-
increased osteoblast but decreased osteoclast activity
-
uniform concentric rings of organized bone matrix
-
"bone pain" spreading out to different areas of the body
Questão 2
Questão
Osteoblasts mature into these cells [blank_start]osteocytes[blank_end] once trapped in the bone matrix; they activate bone formation via [blank_start]altered signalling[blank_end] and apoptosis.
Responda
-
osteocytes
-
altered signalling
Questão 3
Questão
What do osteoblasts do?
Questão 4
Questão
What is characteristic of osteoclasts?
Questão 5
Questão
Where would you have the most interstitial growth?
Responda
-
epiphysis
-
metaphysis
-
diaphysis
-
epiphyseal growth plates
-
periosteum
Questão 6
Questão
[blank_start]Interstitial[blank_end] growth is [blank_start]lengthening[blank_end] growth. This is due to increased number of matrix-depositing cells. [blank_start]Appositional[blank_end] growth is [blank_start]widening[blank_end] growth. This is due to increased matrix deposition by the same number cells.
Responda
-
Interstitial
-
Appositional
-
widening
-
lengthening
Questão 7
Questão
In terms of calcium metabolism, the thyroid releases what hormone?
Questão 8
Questão
Calcitonin causes increased calcium deposition in bone by inhibiting bone resorption.
Questão 9
Questão
What does parathyroid hormone do?
Responda
-
increase osteoclast activity
-
increase osteoblast activity
-
increase osteocyte activity
-
decrease osteoclast activity
-
decrease osteoblast activity
-
decrease osteocyte activity
Questão 10
Questão
Falling onto an outstretched hand/wrist causes what type of fracture most commonly?
Responda
-
scaphoid fracture
-
radial styloid fracture
-
humeral fracture
-
3rd metacarpal fracture
-
ulnar styloid process
-
lunate fracture
Questão 11
Questão
What are bones of the hand?
Responda
-
scaphoid
-
lunate
-
triquetrum
-
pisiform
-
trapezium
-
trapezoid
-
capitate
-
hamate
Questão 12
Questão
What nerve would you damage if you were to break the shaft of the humerus?
Responda
-
radial
-
axillary
-
musculocutaneous
-
medial
-
ulnar
Questão 13
Questão
If the radial nerve is damaged, how might it present?
Responda
-
wrist drop even with fully extended forearm/arm
-
inability to abduct arm
-
inability to flex elbow
-
inability to flex shoulder
-
Benedict claw with fully extended forearm/arm
Questão 14
Questão
What does the musculocutaneous innervate muscle-wise?
Responda
-
flexor muscles of the arm
-
flexor muscles of the forearm
-
extensor muscles of the arm
-
extensor muscles of the forearm
-
3.5 fingers of the hand
Questão 15
Questão
What does the axillary innervate muscle-wise?
Responda
-
deltoid, teres minor (shoulder muscles)
-
posterior arm flexor muscles
-
posterior forearm extensor muscles
Questão 16
Questão
What does the radial nerve NOT innervate muscle-wise?
Questão 17
Questão
What does musculocutaneous innervate muscle-wise?
Questão 18
Questão
What does ulnar nerve innervate muscle-wise?
Responda
-
posterior forearm muscles
-
posterior arm muscles
-
anterior forearm muscles
-
anterior arm muscles
-
anterior medial 2 fingers
-
posterior lateral 2 fingers
Questão 19
Questão
If there is loss of elbow flexion (can't flex biceps), there is damage to the [blank_start]musculocutaneous[blank_end] nerve.
Questão 20
Questão
if there is shoulder weakness or you're unable to abduct shoulder, then there is damage to the [blank_start]axillary[blank_end] nerve.
Questão 21
Questão
A hand of benediction is sign of damage to the [blank_start]median[blank_end] nerve.
Questão 22
Questão
Being unable to abduct or adduct the last 2 fingers is indicative of damage to the [blank_start]ulnar[blank_end] nerve.
Questão 23
Questão
What does the ulnar provide sensory innervation to?
Questão 24
Questão
What does the median provide sensory innervation to?
Responda
-
anterior 3.5 lateral fingers
-
posterior 3.5 lateral fingers
-
anterior 1.5 lateral fingers
-
posterior 1.5 lateral fingers
Questão 25
Questão
What does radial nerve provide sensory innervation to?
Responda
-
lateral arm
-
posterior forearm
-
posterior hand
-
anterior hand
-
anterior forearm
-
medial arm
Questão 26
Questão
The axillary nerve innervates the...in sensory wise
Questão 27
Questão
Musculocutaneous provides sensory innervation to lateral forearm down to the thenar prominence (at the base of the thumb.)
Questão 28
Questão
Numbness at the back of the wrist and hand is due to damage to the sensory innervation by the [blank_start]radial[blank_end] nerve.
Questão 29
Questão
Damage to the [blank_start]median[blank_end] nerve will lead to parethesia to the lateral 3 anterior fingers.
Questão 30
Questão
Loss of sensation in the median of the hand and the medial first 2 fingers is damage to the [blank_start]ulnar[blank_end] nerve.
Questão 31
Questão
Damage to the radial nerve leads to wrist drop. What are some pathologies in which the radial nerve gets hurt?
Questão 32
Questão
How might you injure the axillary nerve?
Responda
-
dislocation of the humeral head
-
surgical neck of the humerus fracture
-
dislocation of the clavicle
-
pulling the deltoid muscle
Questão 33
Questão
You might harm the musculocutaneous nerve via a medial epicondyle fracture.
Questão 34
Questão
A winged scapula is indicative of damage to the [blank_start]long thoracic nerve[blank_end] (spinal roots C5-C7.)
Questão 35
Questão
The spinal roots of the musculocutaneous nerve are (in numerical order from least to greatest) are [blank_start]C5[blank_end], [blank_start]C6[blank_end], and [blank_start]C7[blank_end].
Questão 36
Questão
The Axillary nerve is from the roots [blank_start]C5[blank_end] and [blank_start]C6[blank_end] (in numerical order.)
Questão 37
Questão
The radial nerve is from the spinal roots [blank_start]C5[blank_end] to [blank_start]T1[blank_end].
Questão 38
Questão
The ulnar nerve is from the spinal roots of [blank_start]C8[blank_end] and [blank_start]T1[blank_end].
Questão 39
Questão
The spinal roots of the median nerve is [blank_start]C5[blank_end] or [blank_start]C6[blank_end] to [blank_start]T1[blank_end].
Questão 40
Questão
Which of these myotomes and action pairings are correct?
Responda
-
C4: shoulder elevation
-
C5: chicken abduction (wings)
-
C6: elbow flexion
-
C6: wrist extension
-
C7: elbow extension
-
C7: wrist flexion
-
C8: thumb extension (thumbs up)
-
T1: finger abduction (fanned fingers)
-
C6: wrist flexion
-
C6: elbow extension
Questão 41
Questão
What is true regarding Erb's palsy?
Responda
-
damage to the upper part of the brachial plexus (C5 and C6)
-
damage to the lower part of the brachial plexus (C7 C8 and T1)
-
motorbike accidents can cause this
-
improper birthing techniques (pull baby's head against pelvic bones while labor) can cause this
-
landing on an outstretched arm from a big height can cause this
-
results in a "waiter's tip"
-
results in a "clawed hand"
-
damage to the axillary nerve
-
damage to the suprascapular nerve
-
damage to the musculocutaneous nerve
Questão 42
Questão
What is the myasthenia gravis?
Responda
-
At the neuromuscular junction, the body produces antibodies against the acetylcholine receptors
-
Intense morning sickness that needs anti-emetics as treatment
-
the gradual degradation of muscle fibers, starting from top of the head to bottom of the feet
-
loss of sensation in some or all motor units of certain muscles
Questão 43
Questão
How might myasthenia gravis present?
Questão 44
Questão
How would you manage myasthenia gravis?
Responda
-
acetylcholine esterase inhibitors
-
acetylcholine reuptake enhancers
-
acetylcholine esterase activators
-
acetylcholine agonists
Questão 45
Questão
The [blank_start]abdominal aorta[blank_end] bifurcates into the [blank_start]right common illiac[blank_end] and the [blank_start]left common illiac[blank_end]. The right illiac again bifurcates into the [blank_start]internal illiac[blank_end] and the [blank_start]external illiac[blank_end]. The external illiac becomes the [blank_start]right femoral[blank_end], which is the deep artery of the right thigh. In the popliteal fossa, the right femoral becomes the right [blank_start]popliteal[blank_end] artery. The right popliteal further bifurcates into the [blank_start]right anterior tibial[blank_end] and the [blank_start]right posterior tibial.[blank_end] The right posterior tibial, which is the pulse felt at the ankle, becomes the [blank_start]posterior right fibular.[blank_end] The right anterior tibial becomes the right [blank_start]dorsalis pedalis[blank_end].
Questão 46
Questão
Which of the following could cause carpal tunnel syndrome?
Responda
-
pregnancy
-
rheumatoid arthiritis
-
repetitive use of hands
-
septic arhritis
-
osteomalacia
-
osteoporosis
Questão 47
Questão
Compression of the [blank_start]median[blank_end] nerve as it travels through the [blank_start]carpal[blank_end] [blank_start]tunnel[blank_end] in the wrist is Carpal Tunnel Syndrome.
Questão 48
Questão
How does Carpal Tunnel Syndrome present?
Questão 49
Questão
What are management options of the carpal tunnel syndrome?
Responda
-
local corticosteroids
-
night time splinting
-
day time splinting
-
anabolic steroids
-
always surgical decompression
-
if severe surgical decompression
-
avoid further injury via strain
Questão 50
Questão
What are the nerves of the lower limb?
Questão 51
Questão
The [blank_start]sural[blank_end] nerve only innervates sensory-wise. It innervates the skin of the [blank_start]posterior[blank_end] leg and [blank_start]lateral[blank_end] foot.
Questão 52
Questão
What does the sciatic innervate muscle-wise?
Responda
-
the posterior compartment of the thigh
-
the anterior compartment of the thigh
-
lateral compartment of the thigh
-
the medial compartment of the thigh
Questão 53
Questão
What does the femoral nerve innervate muscle-wise?
Responda
-
anterior thigh
-
posterior thigh
-
lateral thigh
-
medial thigh
Questão 54
Questão
What does the obturator nerve innervate muscle wise?
Responda
-
anterior thigh
-
posterior thigh
-
lateral thigh
-
medial thigh
Questão 55
Questão
What does the common fibular deep branch innervate muscle wise?
Responda
-
anterior leg
-
posterior leg
-
lateral leg
-
medial leg
Questão 56
Questão
What does the superficial branch of the common fibular innervate muscle-wise?
Responda
-
anterior leg
-
posterior leg
-
lateral leg
-
medial leg
Questão 57
Questão
What does the tibial nerve innervate muscle-wise?
Responda
-
posterior leg
-
anterior leg
-
medial leg
-
lateral leg
-
sole of the foot
-
top of the foot
Questão 58
Questão
The femoral nerve's sensory innervation includes the [blank_start]anterior[blank_end] thigh and [blank_start]medial[blank_end] leg.
Questão 59
Questão
The obturator nerve's sensory innervation is the [blank_start]medial[blank_end] thigh.
Questão 60
Questão
The [blank_start]deep[blank_end] branch of the common fibular's sensory innervation is the skin of the upper lateral leg.
Questão 61
Questão
The deep branch of the common fibular's sensory innervation is the [blank_start]lower[blank_end] [blank_start]lateral[blank_end] leg and [blank_start]dorsal[blank_end] foot.
Questão 62
Questão
Both the [blank_start]sciatic[blank_end] nerve (which bifurcates in the [blank_start]popliteal[blank_end] fossa into the [blank_start]tibial[blank_end] nerve and the common fibular nerve) and the [blank_start]tibial[blank_end] nerve innervate (sensory-wise) the [blank_start]posterior[blank_end] thigh and [blank_start]posterior[blank_end] leg and [blank_start]plantar[blank_end] foot.
Responda
-
sciatic
-
popliteal
-
tibial
-
tibial
-
posterior
-
posterior
-
plantar
Questão 63
Questão
The sciatic nerve's spinal roots are [blank_start]L4-S3[blank_end].
Responda
-
L4-S3
-
L2-S3
-
L1-L2
-
L3-S2
-
L4-S2
Questão 64
Questão
Dorsiflexion is a sign of damage to what nerve?
Questão 65
Questão
Inability to dorsiflex (so basically having a foot drop) is indicative of damage to what nerve?
Questão 66
Questão
What movements does the femoral nerve allow?
Responda
-
flexion of hips
-
extension of the knee
-
extension of the hips
-
flexion of the knees
-
abduction of the leg
-
adduction of the leg
Questão 67
Questão
What innervates hip extension and knee flexion?
Responda
-
Inferior gluteal
-
sciatic nerve
-
superior gluteal
-
tibial
-
common fibular
Questão 68
Questão
The [blank_start]obturator[blank_end] nerve allows hip adduction. On the other hand, the [blank_start]superior[blank_end] [blank_start]gluteal[blank_end] nerve allows hip abduction.
Responda
-
obturator
-
superior
-
gluteal
Questão 69
Questão
What are the main types of arthritis?
Questão 70
Questão
[blank_start]Primary[blank_end] osteoarthritis and [blank_start]secondary[blank_end] osteoarthritis are the two types of osteoarthritis.
Questão 71
Questão
The three types of inflammatory arthritis: rheumatoid, [blank_start]crystal-induced,[blank_end] and [blank_start]psoriatic[blank_end].
Responda
-
crystal-induced,
-
psoriatic
Questão 72
Questão
What are the two types of crystal-induced arthritis?
Responda
-
gout
-
pseudogout
-
rheumatoid
-
psoriatic
-
none of the above
Questão 73
Questão
What is a degenerative disease that affects the joints, often due to wear and tear of articular cartilage?
Responda
-
osteoarthritis
-
synovitis
-
crepitus
-
joint stiffness
-
subarticular sclerosis
Questão 74
Questão
How might osteoarthritis present?
Responda
-
joint stiffness in the evening/morning
-
generally worse after walking
-
palpable bony swelling on the hands' interphalangeal joints
-
reduced range of motion
-
crepitus in the joints
-
insomnia
-
generalized swelling around major joints
-
locked joints
-
synovitis
Questão 75
Questão
An X-ray investigation of osteoarthritis will show...
Responda
-
reduced joint space
-
subarticular sclerosis
-
osteophytes
-
bony cysts
-
glued up joint space
-
cartilage cysts
-
osteocytes
Questão 76
Questão
For osteoarthritis, the only management is supportive/palliative.
Questão 77
Questão
What is an autoimmune disease that also ends in joint destruction?
Responda
-
rheumatoid arthritis
-
septic arthritis
-
osteoarthritis
-
gout
Questão 78
Questão
What is characteristic of rheumatoid arthritis?
Responda
-
specific joint pain in the morning
-
specific joint pain in the evening
-
joints affected symetrically
-
joint inflammation
-
joints affected asymetrically
Questão 79
Questão
All of these are part of the management of rheumatoid arthritis BUT
Questão 80
Questão
Which of the following regarding the investigation of rheumatoid arthritis is true?
Responda
-
will find rheumatoid factor in serum
-
x-ray will reveal bone erosion
-
x-ray will reveal reduced joint space
-
periarticular osteopenia
-
visible deformity
-
x-ray will reveal
-
excessive bone growth
Questão 81
Questão
The deposition of monosodium urate crystals in joints is a type of arthritis called [blank_start]gout[blank_end]. This usually happens if there are high levels of [blank_start]uric[blank_end] acid in the blood. The risk factors are [blank_start]obesity[blank_end] and [blank_start]purine[blank_end] (one of the building blocks of DNA) rich food. The most common occurence is at the big [blank_start]toe[blank_end] joint. Symptoms include [blank_start]synovitis[blank_end] (swelling of the joint), [blank_start]malaise[blank_end] (general ill-feeling), and [blank_start]tophi[blank_end] [blank_start]lumps[blank_end] (crystals.) These crystals are visible under polarized light microscopy. The primary way to test for this is to take [blank_start]aspirate[blank_end] fluid in the joint, gram stain it to rule out septic arthritis, and test the fluid for levels of uric acid.
Responda
-
gout
-
uric
-
purine
-
obesity
-
toe
-
synovitis
-
malaise
-
tophi
-
lumps
-
aspirate
Questão 82
Questão
The treatment plan is for what?
1. NSAIDs
2. Colchicine
3. Corticosteroids
Responda
-
chronic gout
-
acute gout
-
goutisis
-
pseudogout
Questão 83
Questão
Other than lifestyle changes to reduce urate levels, we give those with [blank_start]chronic[blank_end] [blank_start]gout[blank_end] the drug allopurinol.
Questão 84
Questão
Accumulation of monosodium urate monohydrate crystals in joints causes pseudogut as well.
Questão 85
Questão
What is of clinical importance regarding septic arthritis?
Responda
-
medical emergency
-
take the aspirate fluid in join and gram stain it
-
take a blood culture (full blood count) and see if there's a high amount of leukocytes
-
take a blood culture (full blood count) and see if there's a high amount of c-reactive protein
-
x-ray will show increased joint space
-
x-ray will show decreased joint space
-
chronic/gradual development
-
to manage, should drain aspirate fluid
-
to manage, should give antibiotics
-
presents like an infection plus reduced joint functionality and synovitis
Questão 86
Questão
Prostacyclin is prostaglandin [blank_start]12[blank_end], which is produced by the [blank_start]epithelium[blank_end]. Prostacyclin prevents excess [blank_start]platelet[blank_end] [blank_start]aggregation[blank_end] during the platelet plug.
Responda
-
12
-
epithelium
-
platelet
-
aggregation
Questão 87
Questão
[blank_start]Thrombocytoplenia[blank_end] is when there are too few platelets in the body. It can be treated with [blank_start]thrombopoietin[blank_end], which will increase the platelet number. It takes [blank_start]6[blank_end] days for progress to be apparent though.
Responda
-
Thrombocytoplenia
-
thrombopoietin
-
6
Questão 88
Questão
Platelets only adhere to smooth epithelial surfaces.
Questão 89
Questão
[blank_start]Von[blank_end] [blank_start]Willebrand[blank_end] Disease is when a person is missing vWF and therefore have difficulty with [blank_start]hemostasis[blank_end] (the stopping of bloodloss.)
Responda
-
Willebrand
-
Von
-
hemostasis
Questão 90
Questão
If there is a suspicion of liver disease, one should check if [blank_start]coagulation[blank_end] is affected because it very well could be.
Questão 91
Questão
Coagulation can be affected in:
diseases affecting [blank_start]protein[blank_end] [blank_start]formation[blank_end]
[blank_start]genetic[blank_end] diseases of the clotting [blank_start]factors[blank_end]
Responda
-
protein
-
formation
-
genetic
-
factors
Questão 92
Questão
There are 2 coagulation pathways: they meet up at factor [blank_start]10[blank_end].
The intrinsic pathway begins with factor [blank_start]12[blank_end]. This is when the [blank_start]inside[blank_end] of the blood vessel gets damage without any necessary external damage. Ex: [blank_start]hypertension[blank_end] (erodes.)
The extrinsic pathways begin with factor [blank_start]3[blank_end]. Damage from [blank_start]outside[blank_end] to the blood vessel. Usually accompanies tissue damage.
Responda
-
10
-
12
-
3
-
hypertension
-
inside
-
outside
Questão 93
Questão
The outside aspect of a scab is called an [blank_start]eschar[blank_end].
Questão 94
Questão
What is true regarding vitamin K?
Responda
-
produces anticoagulant protein c
-
produces coagulant protein z
-
produces anticoagulant protein s
-
produces factor 7
-
produces factor 9
-
produces prothrombin
-
produces factor 10
-
produces fibrinogen
-
produces factor 5
Questão 95
Questão
Vitamin K helps with bone metabolism by increasing calcification.
Questão 96
Questão
Vitamin K is from kale and kiwi.
Questão 97
Questão
Vitamin K is stored in muscle
Questão 98
Questão
The "tea and toast" diet is associated with vitamin [blank_start]B[blank_end][blank_start]12[blank_end] deficiency. Patients can present as [blank_start]weakness[blank_end], paresthesia (tingliness), and [blank_start]irritability[blank_end]. Vegetarians and [blank_start]vegans[blank_end] often have this. B12 helps make the [blank_start]myelin[blank_end] [blank_start]sheath[blank_end] in neurons.
Responda
-
B
-
12
-
weakness
-
irritability
-
myelin
-
sheath
-
vegans
Questão 99
Questão
[blank_start]Allodynia[blank_end] is when the patient complains that "everything" is painful, even stimuli that are not usually painful.
Questão 100
Questão
[blank_start]Hyperalgesia[blank_end] is when you have an increased pain response to painful stimulus.
Questão 101
Questão
Primary healing is when you actively bring together both edges of the wound to stimulate heealing.
Questão 102
Questão
Secondary healing is when you leave the wound alone to heal
Questão 103
Questão
Warfarin is given following
Responda
-
a prothrombin time test
-
a K reductase time test
-
a Synacthen test
-
a plasmin time test
-
a water deprifation test
Questão 104
Questão
Warfarin is an anticoagulant.
Questão 105
Questão
Warfarin works essentially by blocking the enzyme [blank_start]vitamin[blank_end] [blank_start]K[blank_end] [blank_start]reductase[blank_end], and thus blocks all the stuff said vitamin makes. It is prescribed for heart conditions--such as [blank_start]atrial[blank_end] [blank_start]fibrillation[blank_end]--and for thrombotic conditions--[blank_start]deep[blank_end] [blank_start]vein[blank_end] thrombosis and [blank_start]pulmonary[blank_end] embolisms are the classics. Also, it is given post [blank_start]orthopedic[blank_end] surgery.
Responda
-
vitamin
-
K
-
reductase
-
atrial
-
fibrillation
-
deep
-
vein
-
pulmonary
-
orthopedic
Questão 106
Questão
Vitamin K enhances the functionality of Warfarin.
Questão 107
Questão
Antithrombin III deficiency is a hereditary, relatively harmless, and common condition.
Questão 108
Questão
DVT and pulmonary embolisms are both complications of Antithrombin III deficiency.
Questão 109
Questão
Warfarin acts on the thrombus by dissolving it.
Questão 110
Questão
TPA ([blank_start]tissue[blank_end] [blank_start]plasminogen[blank_end] [blank_start]activator[blank_end]) is used in drugs dealing with thrombotic problems. It [blank_start]dissolves[blank_end] the clot.
Responda
-
tissue
-
plasminogen
-
activator
-
dissolves
Questão 111
Questão
What causes Hemophilia A?
Responda
-
Factor 8 deficiency
-
Factor 9 deficiency
-
Factor 12 deficiency
-
Factor 5 deficiency
Questão 112
Questão
What is Hemophilia B due to?
Responda
-
Factor 7 deficiency
-
Factor 5 deficiency
-
Factor 9 deficiency
-
Factor 11 deficiency
Questão 113
Questão
[blank_start]Vasculogenesis[blank_end] is the formation of new blood vessels completely from scratch from [blank_start]endothelial[blank_end] precursor cells.
Responda
-
Vasculogenesis
-
endothelial
Questão 114
Questão
Myofibroblasts need a lot of extracellular matrix.
Questão 115
Questão
Mature tissue contains [blank_start]dense[blank_end] collagen (collagen [blank_start]I[blank_end]) and blood channels. It is [blank_start]acellular[blank_end] connective tissue.
Questão 116
Questão
What is true regarding Hypertrophic scars?
Questão 117
Questão
What is true regarding contracture scars?
Questão 118
Questão
What is true regarding keloid scars?
Questão 119
Questão
Sunken scars have a [blank_start]pitted[blank_end] kind of appearance. An example: [blank_start]chickenpox[blank_end] scars.
Questão 120
Questão
Scar treatment is often unecessary.
Questão 121
Questão
Which of these are ways to treat scars?
Responda
-
topical silicone gel
-
pressure dressings
-
steroids
-
make- up
-
cosmetic surgery
-
plastic surgery
-
flucloxacillin
-
acupuncture