General Pathoanatomy Final MCQs (301-400)- 3rd Year- PMU

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General Pathoanatomy Final MCQs (301-400)- 3rd Year- PMU
Med Student
Quiz por Med Student , atualizado more than 1 year ago
Med Student
Criado por Med Student mais de 6 anos atrás
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Resumo de Recurso

Questão 1

Questão
Indicate the correct statement(s)
Responda
  • granulation tissue is rich of capillaries and cells
  • granulation tissue is rich in collagen fibres and fibroblasts and contains less blood vessels
  • granulation tissue is the immature connective tissue
  • fibrous tissue is immature connective tissue

Questão 2

Questão
What is hyper-granulation?
Responda
  • mature connective tissue
  • hypertrophic tumor-like cicatrix/scar
  • greater amount of granulation tissue
  • none of the above

Questão 3

Questão
What is a scar?
Responda
  • hypertrophic granulation tissue
  • mature connective tissue
  • hypertrophic tumor-like cicatrix
  • none of the above

Questão 4

Questão
What is a keloid?
Responda
  • hypertrophic tumor-like cicatrix
  • mature connective tissue
  • greater amount of granulation tissue
  • none of the above

Questão 5

Questão
Which stain can be used to prove of scarring (cicatrix) of the heart?
Responda
  • Van Gieson
  • Peris
  • Congo Red
  • PAS

Questão 6

Questão
Which of the could not be seen in rheumatoid nodules?
Responda
  • Fibrinoid necrosis
  • Epitheloid cells
  • Langhans cells
  • Lymphocytes

Questão 7

Questão
Indicate the correct statement(s) for the polyarteriitis nodosa.
Responda
  • it is an autoimmune disease
  • it affects mostly the elastic arteries
  • there is accumulation of glucosaminoglycans in the vessel walls which can be demonstrated with metachromasia with Toluidin Bleu
  • the branches of the pulmonary arteries are affected

Questão 8

Questão
Anaphylactic hypersensitivity reactions are related to:
Responda
  • Hemolytic anemia
  • Hashimoto thyroiditis
  • Allergic rhinitis
  • Bronchial asthma

Questão 9

Questão
Cytotoxic hypersensitivity reactions are related to:
Responda
  • hashimoto thyroiditis
  • hemolytic anemia
  • allergic rhinitis
  • nodosal poyarteriitis

Questão 10

Questão
Immune complexes mediated hypersensitivity reactions are related to:
Responda
  • polyartheriitis nodosa
  • rheumatoid arthritis
  • hemolytic anemia
  • tuberculosis

Questão 11

Questão
Cell mediated hypersensitivity reactions are related to:
Responda
  • Tuberculosis
  • Polyarteriitis nodosa
  • Bronchial asthma
  • Hashimoto thyroiditis

Questão 12

Questão
Indicate characteristics of the benign tumors.
Responda
  • expansive type of growth
  • fast speed of growth
  • invading and destroying the adjacent tissues
  • in general they have good prognosis

Questão 13

Questão
Indicate characteristics of the benign tumors
Responda
  • infiltrative growth
  • slow, long term developntcnt
  • usually they don't recur after complete surgery
  • their microscopic structure shows only tissue atypia

Questão 14

Questão
Indicate correct characteristics of the malignant tumors.
Responda
  • expansive growth
  • fast speed of growth
  • they have poor prognosis in general
  • composed of differentiated, mature cells

Questão 15

Questão
Indicate correct characteristics of the malignant tumors.
Responda
  • infiltrative growth
  • microscopic structure shows both tissue and cells atypia
  • good prognosis in general
  • metastasizing

Questão 16

Questão
Which is the most common way of metastasizing of epithelial tumors?
Responda
  • by lymphatics (lymphogenic metastases)
  • with blood (hematogenic metastases)
  • by cerebrospinal fluid
  • none of the above

Questão 17

Questão
What is papilloma?
Responda
  • malignant tumor of the covering epithelium
  • benign tumor of glandular epithelium
  • benign tumor of cover type epithelium
  • benign soft tissue tumor

Questão 18

Questão
Indicate the correct characteristic(s) for papilloma
Responda
  • it has tree-like stroma covered by differentiated stratified squamous epithelium
  • it has tree-like stroma covered by undifferentiated squamous epithelium with signs of cell atypia
  • stroma and parenchyma are difficult to distinguish
  • it doesn't have a capsule

Questão 19

Questão
What is the term used for malignant tumors of cover type epithelium?
Responda
  • adenocarcinoma
  • papilloma
  • carcinoma
  • sarcoma

Questão 20

Questão
What is the term used for malignant tumors of glandular type epithelial origin?
Responda
  • adenocarcinoma
  • adenoma
  • carcinoma
  • carcino-adenoma

Questão 21

Questão
What is the term used for benign tumors of glandular type epithelial origin?
Responda
  • papilloma
  • adenoma
  • teratoma
  • adenocarcinoma

Questão 22

Questão
Point the correct statement(s) about basal cell carcinoma.
Responda
  • it develops only on the skin
  • it can develop at any place with squamous epithelium
  • it characterizes with early lymphogenic and hematogenic metastases
  • very often it recurs at the same place after surgery

Questão 23

Questão
Keratinized squamous cell carcinoma:
Responda
  • develops only on the skin
  • can develop at any place with squamous epithelium
  • is highly undifferenciated malignant tumor
  • is a tumor composed of more differenciated cells with keratin production

Questão 24

Questão
What kind of structures are the cancer perls?
Responda
  • accumulation of keratin produced by more differentiated malignant cells originating from squamous epithelium
  • pink-coloured homogenous substance located in the centre of the tumor nests
  • accumulation of mucus produced by highly undifferentiated malignant cells located in the centre of the tumor nests
  • pink homogenous substance that accumulates in the stroma of the tumor

Questão 25

Questão
The gross appearance of which tumor is called "ulcus rodens"?
Responda
  • squamous cell carcinoma
  • melanoma
  • basal cell carcinoma
  • adenocarcinoma

Questão 26

Questão
Squamous cell carcinoma develops in the lung after:
Responda
  • acute bronchitis
  • chronic bronchitis accompanied by metaplasia
  • bronchial asthma
  • inhalaton of a foreign body

Questão 27

Questão
Indicate the correct microscopic features of cell atypia
Responda
  • polymorphism of cells and nuclei
  • low nucleus-cytoplasm index
  • typical mitoses
  • monster cells, hyperchromasia and polychromasia of nuclei

Questão 28

Questão
What are the characteristics of the nuclei of the malignant tumors?
Responda
  • polychromasia
  • normal staining pattern
  • hyperchromasia
  • increased nucleo-cytoplasmic index

Questão 29

Questão
Papillary carcinoma of the urinary bladder arises from:
Responda
  • squamous epithelium
  • transitional epithelium
  • glandular epithelium
  • smooth musculature

Questão 30

Questão
What is carcinoma in situ?
Responda
  • malignant tumor limited to the epithelium above the basal membrane
  • malignant tumor destroying the basal membrane but spreading no more than 5mm below it
  • benign tumor limited to the basal membrane
  • benign tumor of a great size compressing the surrounding tissues

Questão 31

Questão
What type of atypia could be seen in the benign tumors of glandular epithelium?
Responda
  • tissue atypia
  • cell atypia
  • both tissue and cell atypia
  • none of the above

Questão 32

Questão
Which staining is used for proving mucus production from gelatinous adenocarcinoma?
Responda
  • Congo red
  • Toluidin bleu, metachromasia is demonstrated
  • PAS reaction with amylase control
  • Van Gieson

Questão 33

Questão
Pericanalicular and intracanalicular are types of:
Responda
  • Ductal carcinoma of the breast
  • Paget's disease
  • Renal cell carcinoma
  • Fibroadenoma

Questão 34

Questão
Kruckenberg tumors are:
Responda
  • metastases from colon adenocarcinoma in the ovaries
  • metastases from pancreatic adenocarcinoma in the ovaries
  • metastases from gastric carcinoma in the ovaries
  • metastases from hepatocellular carcinoma in the ovaries

Questão 35

Questão
Pleomorphic adenoma could be seen mainly:
Responda
  • in the parotid gland
  • in the minor salivary glands
  • in the stomach
  • in the thyroid gland

Questão 36

Questão
Indicate the correct statements about fibroadenoma of the breast.
Responda
  • capsulated and lobulated tumor
  • non-capsulated malignant tumor with invasive growth
  • microscopically it has two types -- intracanalicular and pericanalicuJar
  • seen in older women

Questão 37

Questão
Mark the correct statements about papillary cystadenoma of the ovary:
Responda
  • malignant tumor
  • has cyst-like and papillary structures
  • histological characteristics include serous and mucinous types
  • it is a physiological change related to menstrual cycle

Questão 38

Questão
'Linitis plastica' is a gross subtype of:
Responda
  • gastric cancer
  • pancreatic cancer
  • breast cancer
  • uterine cancer

Questão 39

Questão
Grossly adenocarcinoma of the colon can be:
Responda
  • polypoid
  • ulcerous
  • nodular
  • all of the listed above

Questão 40

Questão
The terms "early cancer" and "advanced cancer" are used for:
Responda
  • gastric adenocarcinoma
  • adenocarcinoma of the endometrium
  • adenocarcinoma of the colon
  • breast cancer

Questão 41

Questão
Malignant tumors from soft tissue are called:
Responda
  • carcinomas
  • word for tissue origin+ suffix " —oma"
  • sarcomas
  • teratomas

Questão 42

Questão
Indicate the characteristics of the sarcomas.
Responda
  • seen in older age
  • grossly they look like "fish meat"
  • they give early hematogenic metastases
  • parenchyma and stroma are equally distributed

Questão 43

Questão
Mark the characteristics of the carcinomas.
Responda
  • seen in young people
  • they metastasize by the blood flow first
  • grossly they have granular surface
  • parenchyma and stroma are equally distributed

Questão 44

Questão
What kind of sarcoma could be seen in an immune deficiency?
Responda
  • Kaposi sarcoma
  • Ewing sarcoma
  • Rhabdomyosarcoma
  • Chondrosarcoma

Questão 45

Questão
Which of the following sarcomas have the worst prognosis?
Responda
  • liposarcoma
  • ostesarcoma
  • fibrosarcoma
  • leiomysarcoma

Questão 46

Questão
What staining can be used to distinguish leiomyoma uteri from fibroma?
Responda
  • Congo red
  • Perls
  • PAS reaction with PAS control
  • Van Gieson

Questão 47

Questão
Point the characteristics of the leiomyosarcoma.
Responda
  • polymorphism of cells and nuclei
  • hyper- and polychromasia of nuclei
  • typical mytoses
  • monster cells

Questão 48

Questão
What is hybernoma?
Responda
  • benign tumor of vascular origin
  • benign tumor originating from brown fat tissue
  • benign tumor originating from striated muscles
  • malignant tumor originating from pigment tissue

Questão 49

Questão
What are the signs of the atypia in a nevus?
Responda
  • asymmetry of the lesion, irregular borders
  • dark color, irregular color of the lesion
  • diameter less than 5mm
  • regular borders

Questão 50

Questão
How should a biopsy be done if there is a suspicion for the melanoma?
Responda
  • incision biopsy
  • punch biopsy
  • excision biopsy
  • brush biopsy

Questão 51

Questão
Point the most common localizations of the teratomas.
Responda
  • ovaries, testis
  • extremities
  • retroperitoneum
  • mediastinum

Questão 52

Questão
Which of the following are organoid teratomas
Responda
  • nephroblastoma
  • cholesteatoma
  • dermoid cyst
  • branchiogcnic cyst

Questão 53

Questão
Which of the following is organismoid teratoma
Responda
  • epidermoid cyst
  • teratocarcinoma
  • dermoid cyst
  • nefroblastoma

Questão 54

Questão
What is a nevus pigmentosus?
Responda
  • tumor-like process
  • tumor process
  • microscopically it contains mature melanocytes
  • microscopically it contains cells with signs of severe atypia and some of them contain melanin

Questão 55

Questão
What is a melanoma?
Responda
  • malignant congenital tumor
  • benign tumor composed of melanocytes
  • malignant tumor of pigment origin
  • none of the above

Questão 56

Questão
What is an achromatic melanoma?
Responda
  • benign form of melanoma
  • melanoma without melanin in the tumor cells
  • type of melanoma which can be proved with immunohistochemical tests
  • melanoma which is more differentiated

Questão 57

Questão
Point possible localizations of the nevus pigmentosus and melanoma.
Responda
  • skin
  • uvea
  • meninges
  • all of the above

Questão 58

Questão
Lentigo maligna, nodular, superficial, acral lentigenous are gross forms of:
Responda
  • melanoma
  • squamous cell carcinoma of the skin
  • basal cell carcinoma of the skin
  • nevus pigmentosus

Questão 59

Questão
Indicate immunohistochemical stains to prove melanoma
Responda
  • HMB-45
  • Ca-125
  • S-100
  • Cytokeratin

Questão 60

Questão
Which of the following tumors do not have a stroma
Responda
  • choriocarcinoma
  • seminoma
  • nephroblstoma
  • neuroblastoma

Questão 61

Questão
Indicate types of nevus pigmentosus:
Responda
  • acquired and congenital
  • junctional, compound, intradermal
  • benign and malignant nevus
  • ectodermal and endodermal nevus

Questão 62

Questão
Melanin is:
Responda
  • lipidogenic pigment
  • proteinogenic pigment

Questão 63

Questão
Where is lipofuscin deposited?
Responda
  • intracellularly
  • extracellularly

Questão 64

Questão
The frozen section ('gefrir') is:
Responda
  • rapid 'intraoperative' histological diagnosis
  • rapid cytology method
  • type of medical imaging
  • histochemical method

Questão 65

Questão
The term „pathognomonic change" means:
Responda
  • unexplained change
  • paradoxical change
  • sufficient to identify the diagnosis/lesion
  • diffuse inflammatory change

Questão 66

Questão
Most likely the cause of centrolobular fatty degeneration of hepatocytes is:
Responda
  • diabetes
  • intoxication
  • hypoxia
  • overfeeding

Questão 67

Questão
Hyaline — droplet degeneration has following characteristics:
Responda
  • extracellular
  • intracellular
  • protein accumulation
  • carbohydrate accumulation

Questão 68

Questão
What pigment is formed in the center of the hematoma?
Responda
  • hemosiderin
  • lipofuscin
  • hemomelanin
  • hematoidin

Questão 69

Questão
In which blood vessels are formed most frequently mixed thrombi?
Responda
  • large veins
  • arteries
  • capillaries
  • venules

Questão 70

Questão
Squamous cell carcinoma occurs most frequently in:
Responda
  • stomach
  • skin
  • bladder
  • larynx

Questão 71

Questão
Hyperemic-hemorrhagic zone occurs in:
Responda
  • tophi urici
  • nodular amyloidosis
  • anemic infarction
  • pneumonia

Questão 72

Questão
Which types of bleeding occur in the digestive system?
Responda
  • hemothorax
  • hemoptysis
  • melena
  • hematemesis

Questão 73

Questão
Which of the following cell damages are irreversible?
Responda
  • necrosis
  • apoptosis
  • vacuolar degeneration
  • cellular edema

Questão 74

Questão
Left ventricular hypertrophy can develop in:
Responda
  • cor pulmonale
  • systemic hypertension
  • mitral stenosis
  • aortic stenosis

Questão 75

Questão
Cancer cells which show no resemblance to the tissue from which the tun originates are called:
Responda
  • undifferentiated carcinoma
  • well-differentiated carcinoma
  • scirrhous type carcinoma
  • histioid cancer

Questão 76

Questão
Which of the following is correct for the mechanical jaundice?
Responda
  • indirect bilirubin prevails in blood
  • elevated urine urobilinogen
  • elevated urine bilirubin
  • stools are hyperpigmented

Questão 77

Questão
Basal cell carcinoma is localized most frequently on:
Responda
  • the skin of the forearm
  • the skin of the lower limbs
  • the skin on the palms
  • skin of the face

Questão 78

Questão
Caseous necrosis is characteristic for:
Responda
  • specific inflammation
  • tuberculosis
  • enzyme fat necrosis
  • chronic pyelonephritis

Questão 79

Questão
Bilaterally, on the skin of the eyelids of a young woman are seen yellow nodules with the size of a grain of rice. What is it?
Responda
  • xanthelasmas
  • nevus
  • efelides
  • hemosiderin deposition

Questão 80

Questão
Which of the following are protein accumulations?
Responda
  • in the epithelial cells of renal tubules
  • russel bodies
  • bodies of Mallory
  • asteroid cells

Questão 81

Questão
Hemorrhagic infarction develops in:
Responda
  • organs with end type arteries (end type blood supply)
  • blockage of arterioles
  • previous venous stasis
  • organs with double blood supply

Questão 82

Questão
How do we call the local depigmentation of the skin?
Responda
  • vitiligo
  • hemosiderosis
  • albinism
  • ohronosis

Questão 83

Questão
What kinds of techniques are used for the detection of the lipids:
Responda
  • freezing microtome
  • paraffin method
  • alcohol fixation
  • staining with Sudan Ill

Questão 84

Questão
The sequence of local structural changes in a disease is called
Responda
  • sanogenesis
  • pathogenesis
  • tanatogenesis
  • morphogenesis

Questão 85

Questão
" Tiger Heart " is diagnosed when:
Responda
  • subepicardial fat is increased
  • yellowish lines in the papillary muscles are seen
  • the interventricular septum is injured
  • infarcted area of the left ventricle in seen

Questão 86

Questão
Which of the following is correct for the mechanical jaundice:
Responda
  • it is parenchymal jaundice
  • there is posthepatic occlusion
  • direct bilirubin is increased
  • it is also called hemolytic jaundice

Questão 87

Questão
The risks involved in fast draining of large quantities of acistes are:
Responda
  • development of low oncotic pressure edema
  • bleeding into the abdominal cavity
  • massive arterial hyperemia in the abdominal vessels
  • hemodynamic collapse

Questão 88

Questão
"Mutilation" means :
Responda
  • form of biological mutation
  • pendulum movement of the blood
  • zonal hair loss
  • self amputation of phalanges

Questão 89

Questão
It is true that :
Responda
  • concentric hypertrophy is also called tonogenic
  • eccentric hypertrophy is myogenic
  • hypertrophy can be combined with hyperplasia
  • false type of hypertrophy is hyperplasia

Questão 90

Questão
Sources of fat embolism in the lung are
Responda
  • the bone marrow in the long bones
  • subcutaneous fat
  • liver with fatty degeneration
  • ulcerated atherosclerotic plaque of the aorta

Questão 91

Questão
Which of these factors lead to nutmeg liver?
Responda
  • short venous stasis
  • arterial hyperemia
  • chronic venous congestion
  • mitral stenosis

Questão 92

Questão
In the bronchi and nasal cavity may develop squamous cell carcinoma based on:
Responda
  • hypoplasia
  • histological accommodation
  • anaplasia
  • metaplasia

Questão 93

Questão
Amyloid demonstates following characteristics:
Responda
  • identified with Tioflavin S in fluorescence
  • shows metachromasia with Perls
  • identified with Congo rot in polarized light
  • ultrastructurally has fibrillary structure

Questão 94

Questão
Anaphylactic shock occurs in:
Responda
  • hypersensitivity reactions cytotoxic type
  • response induced by immune complexes
  • atopic reactions
  • delayed type hypersensitivity

Questão 95

Questão
A basal cell carcinoma is localized most frequently on:
Responda
  • the skin of the forearm
  • the skin of the lower limbs
  • the skin on the palms
  • the skin of the face

Questão 96

Questão
Reaction for Prussian blue is used for:
Responda
  • tattoos
  • proof of bilirubin
  • proof of hemosiderin
  • in hemochromatosis

Questão 97

Questão
How could an air embolism be proved:
Responda
  • in the presence of witnesses
  • autopsy in a bathtub
  • puncturing the right ventricle
  • puncturing of the left ventricle

Questão 98

Questão
Which enzymes are involved in a melanogenesis?
Responda
  • hyaluronidase
  • tvrosinase
  • dopa oxidase
  • lipase

Questão 99

Questão
Infarctions of which organs could often lead to the death of the patient?
Responda
  • renal infarction
  • infarction of the spleen
  • infarction of heart
  • cerebral infarction

Questão 100

Questão
In cancers with epithelial origin:
Responda
  • cells are arranged in sheets, nests or cords
  • resemble 'fish meat'
  • metastasize primarily by blood
  • cells show atypia

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