Questão 1
Questão
Indicate the correct statement(s)
Responda
-
granulation tissue is rich of capillaries and cells
-
granulation tissue is rich in collagen fibres and fibroblasts and contains less blood vessels
-
granulation tissue is the immature connective tissue
-
fibrous tissue is immature connective tissue
Questão 2
Questão
What is hyper-granulation?
Questão 3
Questão 4
Questão
What is a keloid?
Questão 5
Questão
Which stain can be used to prove of scarring (cicatrix) of the heart?
Responda
-
Van Gieson
-
Peris
-
Congo Red
-
PAS
Questão 6
Questão
Which of the could not be seen in rheumatoid nodules?
Responda
-
Fibrinoid necrosis
-
Epitheloid cells
-
Langhans cells
-
Lymphocytes
Questão 7
Questão
Indicate the correct statement(s) for the polyarteriitis nodosa.
Responda
-
it is an autoimmune disease
-
it affects mostly the elastic arteries
-
there is accumulation of glucosaminoglycans in the vessel walls which can be demonstrated with metachromasia with Toluidin Bleu
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the branches of the pulmonary arteries are affected
Questão 8
Questão
Anaphylactic hypersensitivity reactions are related to:
Responda
-
Hemolytic anemia
-
Hashimoto thyroiditis
-
Allergic rhinitis
-
Bronchial asthma
Questão 9
Questão
Cytotoxic hypersensitivity reactions are related to:
Responda
-
hashimoto thyroiditis
-
hemolytic anemia
-
allergic rhinitis
-
nodosal poyarteriitis
Questão 10
Questão
Immune complexes mediated hypersensitivity reactions are related to:
Responda
-
polyartheriitis nodosa
-
rheumatoid arthritis
-
hemolytic anemia
-
tuberculosis
Questão 11
Questão
Cell mediated hypersensitivity reactions are related to:
Responda
-
Tuberculosis
-
Polyarteriitis nodosa
-
Bronchial asthma
-
Hashimoto thyroiditis
Questão 12
Questão
Indicate characteristics of the benign tumors.
Questão 13
Questão
Indicate characteristics of the benign tumors
Responda
-
infiltrative growth
-
slow, long term developntcnt
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usually they don't recur after complete surgery
-
their microscopic structure shows only tissue atypia
Questão 14
Questão
Indicate correct characteristics of the malignant tumors.
Questão 15
Questão
Indicate correct characteristics of the malignant tumors.
Questão 16
Questão
Which is the most common way of metastasizing of epithelial tumors?
Questão 17
Questão
What is papilloma?
Responda
-
malignant tumor of the covering epithelium
-
benign tumor of glandular epithelium
-
benign tumor of cover type epithelium
-
benign soft tissue tumor
Questão 18
Questão
Indicate the correct characteristic(s) for papilloma
Responda
-
it has tree-like stroma covered by differentiated stratified squamous epithelium
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it has tree-like stroma covered by undifferentiated squamous epithelium with signs of cell atypia
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stroma and parenchyma are difficult to distinguish
-
it doesn't have a capsule
Questão 19
Questão
What is the term used for malignant tumors of cover type epithelium?
Responda
-
adenocarcinoma
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papilloma
-
carcinoma
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sarcoma
Questão 20
Questão
What is the term used for malignant tumors of glandular type epithelial origin?
Responda
-
adenocarcinoma
-
adenoma
-
carcinoma
-
carcino-adenoma
Questão 21
Questão
What is the term used for benign tumors of glandular type epithelial origin?
Responda
-
papilloma
-
adenoma
-
teratoma
-
adenocarcinoma
Questão 22
Questão
Point the correct statement(s) about basal cell carcinoma.
Responda
-
it develops only on the skin
-
it can develop at any place with squamous epithelium
-
it characterizes with early lymphogenic and hematogenic metastases
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very often it recurs at the same place after surgery
Questão 23
Questão
Keratinized squamous cell carcinoma:
Responda
-
develops only on the skin
-
can develop at any place with squamous epithelium
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is highly undifferenciated malignant tumor
-
is a tumor composed of more differenciated cells with keratin production
Questão 24
Questão
What kind of structures are the cancer perls?
Responda
-
accumulation of keratin produced by more differentiated malignant cells originating from squamous epithelium
-
pink-coloured homogenous substance located in the centre of the tumor nests
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accumulation of mucus produced by highly undifferentiated malignant cells located in the centre of the tumor nests
-
pink homogenous substance that accumulates in the stroma of the tumor
Questão 25
Questão
The gross appearance of which tumor is called "ulcus rodens"?
Responda
-
squamous cell carcinoma
-
melanoma
-
basal cell carcinoma
-
adenocarcinoma
Questão 26
Questão
Squamous cell carcinoma develops in the lung after:
Questão 27
Questão
Indicate the correct microscopic features of cell atypia
Responda
-
polymorphism of cells and nuclei
-
low nucleus-cytoplasm index
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typical mitoses
-
monster cells, hyperchromasia and polychromasia of nuclei
Questão 28
Questão
What are the characteristics of the nuclei of the malignant tumors?
Questão 29
Questão
Papillary carcinoma of the urinary bladder arises from:
Responda
-
squamous epithelium
-
transitional epithelium
-
glandular epithelium
-
smooth musculature
Questão 30
Questão
What is carcinoma in situ?
Responda
-
malignant tumor limited to the epithelium above the basal membrane
-
malignant tumor destroying the basal membrane but spreading no more than 5mm below it
-
benign tumor limited to the basal membrane
-
benign tumor of a great size compressing the surrounding tissues
Questão 31
Questão
What type of atypia could be seen in the benign tumors of glandular epithelium?
Questão 32
Questão
Which staining is used for proving mucus production from gelatinous adenocarcinoma?
Questão 33
Questão
Pericanalicular and intracanalicular are types of:
Questão 34
Questão
Kruckenberg tumors are:
Responda
-
metastases from colon adenocarcinoma in the ovaries
-
metastases from pancreatic adenocarcinoma in the ovaries
-
metastases from gastric carcinoma in the ovaries
-
metastases from hepatocellular carcinoma in the ovaries
Questão 35
Questão
Pleomorphic adenoma could be seen mainly:
Questão 36
Questão
Indicate the correct statements about fibroadenoma of the breast.
Responda
-
capsulated and lobulated tumor
-
non-capsulated malignant tumor with invasive growth
-
microscopically it has two types -- intracanalicular and pericanalicuJar
-
seen in older women
Questão 37
Questão
Mark the correct statements about papillary cystadenoma of the ovary:
Responda
-
malignant tumor
-
has cyst-like and papillary structures
-
histological characteristics include serous and mucinous types
-
it is a physiological change related to menstrual cycle
Questão 38
Questão
'Linitis plastica' is a gross subtype of:
Responda
-
gastric cancer
-
pancreatic cancer
-
breast cancer
-
uterine cancer
Questão 39
Questão
Grossly adenocarcinoma of the colon can be:
Responda
-
polypoid
-
ulcerous
-
nodular
-
all of the listed above
Questão 40
Questão
The terms "early cancer" and "advanced cancer" are used for:
Questão 41
Questão
Malignant tumors from soft tissue are called:
Questão 42
Questão
Indicate the characteristics of the sarcomas.
Responda
-
seen in older age
-
grossly they look like "fish meat"
-
they give early hematogenic metastases
-
parenchyma and stroma are equally distributed
Questão 43
Questão
Mark the characteristics of the carcinomas.
Responda
-
seen in young people
-
they metastasize by the blood flow first
-
grossly they have granular surface
-
parenchyma and stroma are equally distributed
Questão 44
Questão
What kind of sarcoma could be seen in an immune deficiency?
Responda
-
Kaposi sarcoma
-
Ewing sarcoma
-
Rhabdomyosarcoma
-
Chondrosarcoma
Questão 45
Questão
Which of the following sarcomas have the worst prognosis?
Responda
-
liposarcoma
-
ostesarcoma
-
fibrosarcoma
-
leiomysarcoma
Questão 46
Questão
What staining can be used to distinguish leiomyoma uteri from fibroma?
Questão 47
Questão
Point the characteristics of the leiomyosarcoma.
Questão 48
Questão
What is hybernoma?
Responda
-
benign tumor of vascular origin
-
benign tumor originating from brown fat tissue
-
benign tumor originating from striated muscles
-
malignant tumor originating from pigment tissue
Questão 49
Questão
What are the signs of the atypia in a nevus?
Responda
-
asymmetry of the lesion, irregular borders
-
dark color, irregular color of the lesion
-
diameter less than 5mm
-
regular borders
Questão 50
Questão
How should a biopsy be done if there is a suspicion for the melanoma?
Responda
-
incision biopsy
-
punch biopsy
-
excision biopsy
-
brush biopsy
Questão 51
Questão
Point the most common localizations of the teratomas.
Responda
-
ovaries, testis
-
extremities
-
retroperitoneum
-
mediastinum
Questão 52
Questão
Which of the following are organoid teratomas
Responda
-
nephroblastoma
-
cholesteatoma
-
dermoid cyst
-
branchiogcnic cyst
Questão 53
Questão
Which of the following is organismoid teratoma
Responda
-
epidermoid cyst
-
teratocarcinoma
-
dermoid cyst
-
nefroblastoma
Questão 54
Questão
What is a nevus pigmentosus?
Questão 55
Questão
What is a melanoma?
Responda
-
malignant congenital tumor
-
benign tumor composed of melanocytes
-
malignant tumor of pigment origin
-
none of the above
Questão 56
Questão
What is an achromatic melanoma?
Responda
-
benign form of melanoma
-
melanoma without melanin in the tumor cells
-
type of melanoma which can be proved with immunohistochemical tests
-
melanoma which is more differentiated
Questão 57
Questão
Point possible localizations of the nevus pigmentosus and melanoma.
Responda
-
skin
-
uvea
-
meninges
-
all of the above
Questão 58
Questão
Lentigo maligna, nodular, superficial, acral lentigenous are gross forms of:
Questão 59
Questão
Indicate immunohistochemical stains to prove melanoma
Responda
-
HMB-45
-
Ca-125
-
S-100
-
Cytokeratin
Questão 60
Questão
Which of the following tumors do not have a stroma
Responda
-
choriocarcinoma
-
seminoma
-
nephroblstoma
-
neuroblastoma
Questão 61
Questão
Indicate types of nevus pigmentosus:
Responda
-
acquired and congenital
-
junctional, compound, intradermal
-
benign and malignant nevus
-
ectodermal and endodermal nevus
Questão 62
Responda
-
lipidogenic pigment
-
proteinogenic pigment
Questão 63
Questão
Where is lipofuscin deposited?
Responda
-
intracellularly
-
extracellularly
Questão 64
Questão
The frozen section ('gefrir') is:
Questão 65
Questão
The term „pathognomonic change" means:
Questão 66
Questão
Most likely the cause of centrolobular fatty degeneration of hepatocytes is:
Responda
-
diabetes
-
intoxication
-
hypoxia
-
overfeeding
Questão 67
Questão
Hyaline — droplet degeneration has following characteristics:
Questão 68
Questão
What pigment is formed in the center of the hematoma?
Responda
-
hemosiderin
-
lipofuscin
-
hemomelanin
-
hematoidin
Questão 69
Questão
In which blood vessels are formed most frequently mixed thrombi?
Responda
-
large veins
-
arteries
-
capillaries
-
venules
Questão 70
Questão
Squamous cell carcinoma occurs most frequently in:
Responda
-
stomach
-
skin
-
bladder
-
larynx
Questão 71
Questão
Hyperemic-hemorrhagic zone occurs in:
Responda
-
tophi urici
-
nodular amyloidosis
-
anemic infarction
-
pneumonia
Questão 72
Questão
Which types of bleeding occur in the digestive system?
Responda
-
hemothorax
-
hemoptysis
-
melena
-
hematemesis
Questão 73
Questão
Which of the following cell damages are irreversible?
Responda
-
necrosis
-
apoptosis
-
vacuolar degeneration
-
cellular edema
Questão 74
Questão
Left ventricular hypertrophy can develop in:
Responda
-
cor pulmonale
-
systemic hypertension
-
mitral stenosis
-
aortic stenosis
Questão 75
Questão
Cancer cells which show no resemblance to the tissue from which the tun originates are called:
Questão 76
Questão
Which of the following is correct for the mechanical jaundice?
Responda
-
indirect bilirubin prevails in blood
-
elevated urine urobilinogen
-
elevated urine bilirubin
-
stools are hyperpigmented
Questão 77
Questão
Basal cell carcinoma is localized most frequently on:
Questão 78
Questão
Caseous necrosis is characteristic for:
Responda
-
specific inflammation
-
tuberculosis
-
enzyme fat necrosis
-
chronic pyelonephritis
Questão 79
Questão
Bilaterally, on the skin of the eyelids of a young woman are seen yellow nodules with the size of a grain of rice. What is it?
Responda
-
xanthelasmas
-
nevus
-
efelides
-
hemosiderin deposition
Questão 80
Questão
Which of the following are protein accumulations?
Questão 81
Questão
Hemorrhagic infarction develops in:
Questão 82
Questão
How do we call the local depigmentation of the skin?
Responda
-
vitiligo
-
hemosiderosis
-
albinism
-
ohronosis
Questão 83
Questão
What kinds of techniques are used for the detection of the lipids:
Responda
-
freezing microtome
-
paraffin method
-
alcohol fixation
-
staining with Sudan Ill
Questão 84
Questão
The sequence of local structural changes in a disease is called
Responda
-
sanogenesis
-
pathogenesis
-
tanatogenesis
-
morphogenesis
Questão 85
Questão
" Tiger Heart " is diagnosed when:
Responda
-
subepicardial fat is increased
-
yellowish lines in the papillary muscles are seen
-
the interventricular septum is injured
-
infarcted area of the left ventricle in seen
Questão 86
Questão
Which of the following is correct for the mechanical jaundice:
Responda
-
it is parenchymal jaundice
-
there is posthepatic occlusion
-
direct bilirubin is increased
-
it is also called hemolytic jaundice
Questão 87
Questão
The risks involved in fast draining of large quantities of acistes are:
Responda
-
development of low oncotic pressure edema
-
bleeding into the abdominal cavity
-
massive arterial hyperemia in the abdominal vessels
-
hemodynamic collapse
Questão 88
Questão
"Mutilation" means :
Responda
-
form of biological mutation
-
pendulum movement of the blood
-
zonal hair loss
-
self amputation of phalanges
Questão 89
Questão
It is true that :
Responda
-
concentric hypertrophy is also called tonogenic
-
eccentric hypertrophy is myogenic
-
hypertrophy can be combined with hyperplasia
-
false type of hypertrophy is hyperplasia
Questão 90
Questão
Sources of fat embolism in the lung are
Responda
-
the bone marrow in the long bones
-
subcutaneous fat
-
liver with fatty degeneration
-
ulcerated atherosclerotic plaque of the aorta
Questão 91
Questão
Which of these factors lead to nutmeg liver?
Questão 92
Questão
In the bronchi and nasal cavity may develop squamous cell carcinoma based on:
Questão 93
Questão
Amyloid demonstates following characteristics:
Responda
-
identified with Tioflavin S in fluorescence
-
shows metachromasia with Perls
-
identified with Congo rot in polarized light
-
ultrastructurally has fibrillary structure
Questão 94
Questão
Anaphylactic shock occurs in:
Responda
-
hypersensitivity reactions cytotoxic type
-
response induced by immune complexes
-
atopic reactions
-
delayed type hypersensitivity
Questão 95
Questão
A basal cell carcinoma is localized most frequently on:
Questão 96
Questão
Reaction for Prussian blue is used for:
Responda
-
tattoos
-
proof of bilirubin
-
proof of hemosiderin
-
in hemochromatosis
Questão 97
Questão
How could an air embolism be proved:
Responda
-
in the presence of witnesses
-
autopsy in a bathtub
-
puncturing the right ventricle
-
puncturing of the left ventricle
Questão 98
Questão
Which enzymes are involved in a melanogenesis?
Responda
-
hyaluronidase
-
tvrosinase
-
dopa oxidase
-
lipase
Questão 99
Questão
Infarctions of which organs could often lead to the death of the patient?
Responda
-
renal infarction
-
infarction of the spleen
-
infarction of heart
-
cerebral infarction
Questão 100
Questão
In cancers with epithelial origin: