Questão 1
Questão
epidemiology:
[blank_start]80[blank_end]% of diabetes patients are type 2. [blank_start]2-3[blank_end] million people in the UK know they have diabetes. diabetes affects [blank_start]2[blank_end]% of the British population with prevalence increasing.
Responda
-
80
-
70
-
60
-
90
-
2-3
-
1-2
-
3-4
-
4-5
-
2
-
1
-
3
-
4
Questão 2
Questão
which of the following is not a symptom of diabetes?
Questão 3
Questão
what are the diagnostic results that would indicate diabetes?
random glucose >[blank_start]11[blank_end]
fasting glucose >[blank_start]7[blank_end]
HbAc1 >[blank_start]46[blank_end]
Questão 4
Questão
which of the following tests is gold standard for diabetes insipidus?
Responda
-
fasting glucose
-
random glucose
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OGTT
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HbA1c
-
water deprivation test
Questão 5
Questão
which of the following would not cause an inaccurate HbA1c result?
Responda
-
pregnancy
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HIV positive
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end stage CKD
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patients <18
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symptoms for <2 months
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T1DM
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people on steroids
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liver cirrhosis
Questão 6
Questão
symptomatic patients need [blank_start]1[blank_end] or more positive results out of RBG, FBG and HbA1c. asymptomatic patients need [blank_start]2[blank_end] or more.
Questão 7
Questão
diet education for management of diabetes:
T2 = [blank_start]DESMOND[blank_end]
T1 = [blank_start]DAPHNE[blank_end]
Questão 8
Questão
match the insulin to the correct box
Responda
-
actrapid
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humulin S
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insulatard
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humulin I
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insuman basal
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humulin M3
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novorapid and insulin aspart
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humalog and insulin lispro
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apidra and insulin glulisine
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novoMIX 30
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humalog MIX25 and humalog MIX50
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insuman comb (15.25,50)
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levemir and insulin detemir
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lantus and insulin glargine
Questão 9
Questão
match the type 2 diabetes medication to its action:
[blank_start]metformin[blank_end] - reduces hepatic glucose output and increases insulin sensitivity
[blank_start]sulphonylureas[blank_end] - stimulate insulin secretion but can cause weight gain and hypoglycaemia
[blank_start]acarbose[blank_end] - inhibits breakdown of CHO and prevents glucose absorption by slowing carbohydrate digestion and increasing length of satiety
[blank_start]GLP1[blank_end] - stimulate insulin production, enhances beta cells proliferation, reduces appetite, suppresses glucagon secretion, reduces hepatic glucose output, slows gastric emptying, and causes weight reduction
[blank_start]SGLT2 inhibitors[blank_end] - block reabsorption of glucose at the proximal tubules of the kidney to increase glucose excretion in urine
Responda
-
metformin
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sulphonylureas
-
acarbose
-
GLP1
-
SGLT2 inhibitors
Questão 10
Questão
match the type of T2DM to the example
GLP1 - [blank_start]liraglutide[blank_end]
SGLT2 - [blank_start]canagliflozin[blank_end]
sulphonylureas - [blank_start]gliclazide[blank_end]
Responda
-
liraglutide
-
canagliflozin
-
gliclazide
Questão 11
Questão
which of the following is not a diagnostic test for type 1 diabetes?
Questão 12
Questão
in diabetic pre-pregnancy planning the patient must have tight glycaemic control for a minimum of [blank_start]3[blank_end] months preconception.
Questão 13
Questão
which of the following is not a common complication of pregnancy with diabetes?
Questão 14
Questão
which of the following is not a risk factor for gestational diabetes?
Responda
-
BMI >30
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family history
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South-East Asian/African origin
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previous macrosomia >4.5kg
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previous gestational diabetes
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age
Questão 15
Questão
all high risk women are screened for diabetes at 16 weeks
Questão 16
Questão
DKA definition:
glucose is above [blank_start]15[blank_end]mmol/L and ketones are above [blank_start]++[blank_end], venous bicarb is below [blank_start]15[blank_end] or pH is below [blank_start]7.3[blank_end]
Responda
-
15
-
10
-
12
-
17
-
++
-
+
-
+++
-
15
-
20
-
25
-
10
-
7.3
-
7.4
-
7.35
-
7.25
Questão 17
Questão
[blank_start]increased[blank_end] plasma glucose --> [blank_start]positive[blank_end] feedback on beta cells of the pancreas --> [blank_start]increased[blank_end] insulin production --> [blank_start]positive[blank_end] feedback on the liver, muscle and adipose tissue --> [blank_start]positive[blank_end] feedback on glycolysis, glycogenesis, lipogenesis and glucose transport --> [blank_start]decreased[blank_end] plasma glucose --> [blank_start]negative[blank_end] feedback on beta cells of the pancreas
Responda
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increased
-
decreased
-
positive
-
negative
-
decreased
-
increased
-
positive
-
negative
-
negative
-
positive
-
decreased
-
increased
-
negative
-
positive
Questão 18
Questão
which of the following does not counteract the action of insulin?
Responda
-
glucagon
-
catecholamine
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growth hormone
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cortisol
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oestrogen
Questão 19
Questão
insulin deficiency --> lipolysis --> increased free fatty acids --> ketone body production --> metabolic acidosis
Questão 20
Questão
which of the following is not a trigger for a DKA?
Responda
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infection
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MI
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stroke
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trauma
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pregnancy
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SGLT2 inhibitors
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lithium
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clozaline
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cocaine
-
beta blockers
Questão 21
Questão
which of the following is not a symptom of DKA?
Responda
-
confusion
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abdominal pain
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pear drop breath
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vomiting
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polyuria
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polydipsia
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lethargy
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obtundation
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rapid weight loss
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diarrhoea
Questão 22
Questão
which of the following is not a part of management for DKA?
Responda
-
IV fluids
-
IV insulin
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VTE prophylaxis
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potassium supplement
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magnesium supplement
Questão 23
Questão
hypoglycaemia is blood glucose <[blank_start]4[blank_end]mmol/L
Questão 24
Questão
[blank_start]30[blank_end]% of diabetics experience a hypoglycaemic coma once during their lives. [blank_start]10[blank_end]% of type 1 diabetics suffer 1 episode of severe hypoglycaemia per year. [blank_start]50[blank_end]% of type 1 patients have a blood glucose <3.5 on any one night.
Responda
-
30
-
10
-
20
-
5
-
10
-
5
-
15
-
20
-
50
-
30
-
40
-
60
Questão 25
Questão
which of the following is not a symptom of hypoglycaemia?
Responda
-
tremor
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sweating
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tachycardia
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lethargy
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slurred speech
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agression
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falls
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TIA
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irritability
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palpitations
Questão 26
Questão
if glucose is <4mmol/L give 100ml of 20% glucose
Questão 27
Questão
which of the following is not a nerve palsy associated with diabetes
Questão 28
Questão
up to [blank_start]50[blank_end]% of people with a diabetic foot ulcer will die within [blank_start]5[blank_end] years of their index ulcer.
Questão 29
Questão
charcots foot occurs due to small [blank_start]fractures[blank_end] in the foot leading to altered [blank_start]pressure[blank_end]. this leads to foot and ankle [blank_start]deformation[blank_end] which could potentially need to be [blank_start]amputated[blank_end]. treat by [blank_start]immobilising[blank_end] the foot and giving [blank_start]pamidronate[blank_end] and specialised footwear.
Responda
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fractures
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pressure
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deformation
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amputated
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immobilising
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pamidronate