222007
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
aproximadamente 11 anos atrás
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Questão 1
Questão
Which type of protein is conjugated?
Responda
-
One that contains only amino acid residues
-
One that contains prosthetic groups
-
One that is bound to a membrane
Questão 2
Questão
Which of the following means a protein with two identical subunits?
Responda
-
Heteromultimer
-
Homomonomer
-
Homomultimer
Questão 3
Questão
Which of the following proteins types tend to have various roles, as opposed to a single, defined one?
Responda
-
Fibrous
-
Globular
-
Membrane
Questão 4
Questão
Which of the following tend not to be water soluble?
Responda
-
Fibrous
-
Globular
-
Membrane spanning
Questão 5
Questão
What secondary structures tend to make up fibrous proteins?
Responda
-
Long strands
-
Long sheets
-
Short strands
Questão 6
Questão
What is specific about the membrane spanning part of membrane proteins?
Responda
-
They are hydrophobic
-
They are hydrophillic
Questão 7
Questão
Define 'Domain' in reference to protein structure
Responda
-
Independent folding units of the tertiary structure that have independent functions
-
Independent folding units of tertiary structure that have related functions
-
Dependent folding units of secondary structure that have relation functions
-
Dependent folding units of tertiary structure that have related functions
Questão 8
Questão
Define subunit
Responda
-
Independent structures in a quaternary structure
-
Independent structures in a tertiary structure
-
Dependent subunits in a quaternary structure
Questão 9
Questão
What can be the result of a single amino acid mutation in collagen?
Responda
-
Osteoarthritis
-
Osteogenesis imperfecta
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Osteocalcification
Questão 10
Questão
What is Resonance (as pertaining to protein structure)?
Responda
-
Where bond pairs cannot be described as a single Lewis Diagram
-
Where two atoms in separate molecules cause each other to vibrate
-
Where two atoms in separate molecules are more likely to bond to each other than to another atom
Questão 11
Questão
Which is the psi bond?
Responda
-
Between the carbonyl carbon and the alpha carbon
-
Between the alpha carbon and the amide group
-
Between the alpha carbon and the R group
Questão 12
Questão
Which is the phi bond?
Responda
-
Between the alpha carbon and the amide group
-
Between the alpha carbon and the carbonyl carbon
-
Between the alpha carbon and the R group
Questão 13
Questão
What is Steric clashing?
Responda
-
Where the charge of an atom prevents it from being close to another
-
Where the electron arrangement of an atom prevents it from being close to another
-
Where the size of an atom prevents it from being close to another
Questão 14
Questão
Why is a peptide bond planar?
Responda
-
It has a double bond like structure
-
It's electrons clash with that of the psi bond
-
It's electrons clash with the phi bond
Questão 15
Questão
How many residues per turn in an alpha helix?
Responda
-
3.4
-
3.5
-
3.6
Questão 16
Questão
How much does an alpha helix rise per aa?
Responda
-
1.5 angstroms
-
1.6 angstroms
-
1.7 angstroms
Questão 17
Questão
Alpha helices are stabilised by hydrogen bonding with what groups?
Responda
-
Carbonyl oxygen 4 amino acids away
-
Carbonyl oxygen 6 amino acids away
-
Carbonyl oxygen 8 amino acids away
Questão 18
Questão
The stabilising effect of the hydrogen bonds makes a loop of how many atoms?
Responda
-
12
-
13
-
14
Questão 19
Questão
Which of the following destabilize an alpha helix?
Responda
-
Glycine
-
Proline
-
Leucine
-
Glutamic acid
Questão 20
Questão
Beta sheets rise by 3.47A per residue in anti-parallel sheets
Responda
- True
- False
Questão 21
Questão
In parallel sheets, there is a rise of .... per residue
Responda
-
3.25A
-
4.25A
-
2.25A
Questão 22
Questão
3 residues per turn of the strand are pictured as a helix
Responda
- True
- False
Questão 23
Questão
Anti-parallel strands are _ stable than parallel ones
Responda
-
More
-
Less
Questão 24
Questão
Side chains all point the same way (in the plane of the sheet)
Responda
- True
- False
Questão 25
Questão
What is the role of loops?
Responda
-
Connecting alpha and beta sheets
-
Connecting alpha helices and alpha helices
-
Connecting beta sheets and beta sheets
Questão 26
Questão
Loops contain mostly hydrophillic residues & are found on the protein surface
Responda
- True
- False
Questão 27
Questão
What is the role of beta turns?
Responda
-
To allow beta sheets to reverse direction
-
To connect beta sheets together
-
To link protein subunits together
Questão 28
Questão
What two amino acids cannot be contained within a beta sheet?
Responda
-
Proline
-
Argenine
-
Glycine
-
Valine
Questão 29
Questão
Beta turns link the oxygen of the carbonyl group and the hydrogen of the nitrile group 4 residues away
Image:
Beta_Turns (image/jpg)
Responda
- True
- False
Questão 30
Questão
Levinthals Paradox- if a protein folded by trying each fold in a sequence, it would take an impossibly long time to fold correctly. Therefore, protein folding cannot be random or sequential
Responda
- True
- False
Questão 31
Responda
-
The energy change as proteins fold
-
Gibbs free energy
-
Entropy change
Questão 32
Questão
Why are the internal interactions of protein folding unfavorable?
Responda
-
It decreases entropy
-
They're hydrophobic in a hydrophillic environment
-
They prevent the protein from folding correctly
Questão 33
Questão
Non-covalent and hydrophobic effects (which effects free water) decrease enthalpy
Responda
- True
- False
Questão 34
Questão
Change in energy during folding = Internal interactions - (Hydrophobic effect + conformational entropy)
Responda
- True
- False
Questão 35
Questão
Proteins fold towards configurations with the...
Responda
-
lowest energy
-
Highest energy
-
Easiest energy to reach (energy closest to that of unfolded protein)
Questão 36
Questão
What can slow the progress of protein folding?
Responda
-
A local low energy minimum
-
A local high energy minimum
Questão 37
Questão
What is nucleation?
Responda
-
Reversible secondary structure formation
-
Reversible tertiary structure formation
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Reversible quaternary structure formation
Questão 38
Questão
Which of the following happens after nucleation?
Responda
-
The secondary structure aggregation forms a molten globular intermediate
-
Domains adjust to the lowest energy form
Questão 39
Questão
The protein is capable of conformational change after forming
Responda
- True
- False
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