Independent and Supplementary Prescribing

Descrição

Pharmacology quiz using the Independent and Supplementary prescribing text book.
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Quiz por offersforalice, atualizado more than 1 year ago
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Criado por offersforalice mais de 9 anos atrás
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Resumo de Recurso

Questão 1

Questão
Choose the word or phrase from the list below that best completes this sentence. Pharmacokinetics can be described as ________________________
Responda
  • how the drug elicits it's effect in the body.
  • how the body handles a drug.
  • the composition of a drug.
  • the way in which a drug should be stored.

Questão 2

Questão
Choose the word or phrase from the list below that best completes this sentence. Drugs may act locally or systemically. Systemically means that the drug must enter ___________________ in order to be delivered to its site of action.
Responda
  • the brain
  • the circulation
  • the lymph nodes
  • the heart

Questão 3

Questão
Which equation can you use to calculate the amount of a drug that reaches the systemic circulation?
Responda
  • F x dose
  • F/dose
  • F - dose
  • F + (2 x dose)

Questão 4

Questão
Choose the word or phrase from the list below that best completes this sentence. Drugs administered as an IV injection have a bioavailability of _________.
Responda
  • 100
  • 10
  • 1.0
  • 0.1

Questão 5

Questão
What words make up the acronym ADME?
Responda
  • Administration
  • Absorption
  • Distribution
  • Dissolving
  • Making
  • Metabolism
  • Exit
  • Excretion

Questão 6

Questão
Choose the word or phrase from the list below that best completes this sentence. Generally in absorption, drugs move from an area of high concentration to a low concentration via ______________
Responda
  • osmosis.
  • active transport.
  • passive diffusion.

Questão 7

Questão
Choose the word or phrase from the list below that best completes this sentence. When drugs are being absorbed from an area of their low concentration to a higher concentration, they move by _____________
Responda
  • active transport.
  • osmosis.
  • passive diffusion.

Questão 8

Questão
Choose the word or phrase from the list below that best completes this sentence. Cell membranes are composed of a double layer of ____________________
Responda
  • proteins.
  • sugars.
  • phospholipids.
  • ions.

Questão 9

Questão
Water soluble drugs pass cell membranes easier than lipid soluble drugs.
Responda
  • True
  • False

Questão 10

Questão
Choose the word or phrase from the list below that best completes this sentence. The more _______________ a drug, the easier it is for the drug to be absorbed from the small intestine into the circulation.
Responda
  • lipid soluble
  • water soluble

Questão 11

Questão
Un-ionised drugs are lipid soluble. What does un-ionised mean?
Responda
  • The drug carries no charge.
  • The drug is negatively charged.
  • The drug is positively charged.
  • The molecule contains two opposing charges.

Questão 12

Questão
Choose the word or phrase from the list below that best completes this sentence. The small intestine has a large surface area due to it's large number of __________.
Responda
  • villi
  • cillia
  • hairs
  • cells

Questão 13

Questão
Choose the word or phrase from the list below that best completes this sentence. The larger the surface area for drug absorption, the _______ the absorption.
Responda
  • slower
  • quicker

Questão 14

Questão
Where does most drug absorption take place?
Responda
  • Stomach
  • Small Intestine
  • Large Intestine
  • Colon

Questão 15

Questão
The presence of food after a meal will slow gastric emptying.
Responda
  • True
  • False

Questão 16

Questão
Sometimes drugs are prescribed to be taken with food. Why might this be?
Responda
  • To lessen the side effects of a drug by preventing large concentrations from entering systemic circulation at the same time, ensuring a more gradual absorption due to gastric emptying.
  • To mask the bad taste of a drug that is taken orally.
  • To prevent local side effects, like irritation of the stomach lining, caused by drugs like NSAIDs.

Questão 17

Questão
Choose the word or phrase from the list below that best completes this sentence. Some drugs are absorbed from the small intestine into the _____________ and are transported directly into the liver.
Responda
  • renal portal vein
  • cranial portal vein
  • hepatic portal vein

Questão 18

Questão
What is the name of the process by which a drug is fully or partially metabolised by the liver, before entering the systemic circulation?
Responda
  • First pass metabolism
  • Liver/drug degradation
  • First past metabolism

Questão 19

Questão
Hypomotility of the GI tract may result in lower concentrations of drug entering the circulation.
Responda
  • True
  • False

Questão 20

Questão
Blood flow affects absorption.
Responda
  • True
  • False

Questão 21

Questão
Choose the word or phrase from the list below that best completes this sentence. A drug must reach it's site of action in ______________, in order to exert it's effect.
Responda
  • an adequate concentration
  • a membrane bound vesicle
  • a salt solution

Questão 22

Questão
Blood flow affects distribution.
Responda
  • True
  • False

Questão 23

Questão
Blood flow affects distribution. Organs that have high perfusion, e.g. heart, therefore receive drugs slowly.
Responda
  • True
  • False

Questão 24

Questão
Choose the word or phrase from the list below that best completes this sentence. Only ________ drug can cross plasma membranes and therefore exert an effect.
Responda
  • free
  • plasma protein bound
  • albumin bound

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