Questão 1
Questão
What triggers the activation of the adaptive immune system?
Responda
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Pathogen exposure
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Inflammation
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Antibody production
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Phagocytosis
Questão 2
Questão
There are two components of the adaptive immune system. What are they called?
Responda
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Cellular immune system
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Humoral immune system
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Antigenic immune system
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Cytotoxic immune system
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Acquired immune system
Questão 3
Questão
What happens to the response of the immune system on each repeated exposure to a pathogen?
Responda
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It becomes faster
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It becomes more specific
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It causes more inflammation
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It becomes less efficient
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It involves more components of the immune system
Questão 4
Questão
What cells are involved in humoral immunity?
Responda
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B cells
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T cells
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Natural killer cells
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Phagocytes
Questão 5
Questão
What cells are involved in cellular immunity?
Responda
-
B cells
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T cells
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Phagocytes
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Natural killer cells
Questão 6
Questão
Which part of the adaptive immune system produced antibodies?
Questão 7
Questão
The adaptive immune system is able to remember pathogens in case they present again. True or false?
Questão 8
Questão
Which cells express CD4?
Responda
-
T helper cells
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T killer cells
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T regulatory cells
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Plasma B cells
Questão 9
Questão
What is the function of T helper cells?
Responda
-
Activate macrophages
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Help B cells to produce antibodies
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Remember the pathogen in case of repeat infection
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Produce antibodies
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Activate natural killer cells
Questão 10
Questão
Why do we need T regulatory cells?
Responda
-
To control the immune response
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To ensure the immune response is specific
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To prevent the immune system from attacking healthy cells
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To prevent the immune system from attacking normal flora
Questão 11
Questão
Which cells expressed CD8?
Responda
-
T killer cells
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T helper cells
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T regulatory cells
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Plasma B cells
Questão 12
Questão
Which cells have the longest life-span?
Responda
-
T regulatory cells
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Memory B cells
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Plasma B cells
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T helper cells
Questão 13
Questão
How are antibodies separated into classes?
Questão 14
Questão
What is the function of membrane bound antibodies?
Questão 15
Questão
Which type of antibody activates complement?
Questão 16
Questão
Which cells require an antigen presenting cell to activate them?
Questão 17
Questão
Which of the following cells can act as antigen presenting cells?
Responda
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Dendritic cells
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Macrophages
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Natural killer cells
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Plasma B cells
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Mast cells
Questão 18
Questão
Which cells express MHCI?
Responda
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All nucleated cells
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T helper cells
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Antigen presenting cells
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Plasma B cells
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Natural killer cells
Questão 19
Questão
Which of the following cells recognised MHCII?
Questão 20
Questão
Where within the antigen presenting cell is the MHC produced?
Responda
-
Endoplasmic reticulum
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Golgi body
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Ribosome
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Nucleus
Questão 21
Questão
Where is the MCHII complex combined with the antigenic peptides?
Responda
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Endosome
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Endoplasmic reticulum
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Golgi body
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Vesicle
Questão 22
Questão
The T cell is activated when it detects the MHC-antigen complex. True or false?
Questão 23
Questão
Which types of hypersensitivity reaction are mediated by antibodies?
Questão 24
Questão
Which type of hypersensitivity reaction is mediated by IgE?
Questão 25
Questão
Which of the following are examples of hypersensitivity reactions that are mediated by IgE?
Responda
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Asthma
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Pollen allergy
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SLE
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Myasthenia Gravis
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Grave's disease
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Type I diabetes
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Psoriasis
Questão 26
Questão
In a type I hypersensitivity reaction, what needs to happen to the antibodies on repeat exposure for there to be a hypersensitivity reaction?
Questão 27
Questão
Grave's disease is an example of a type II hypersensitivity reaction. What are type II hypersensitivity reactions mediated by?
Questão 28
Questão
What is another example of a type II hypersensitivity reaction?
Responda
-
Myasthenia Gravis
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Asthma
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Type I diabetes
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SLE
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Coeliac disease
Questão 29
Questão
How do the antibodies in type II hypersensitivity reactions cause disease?
Responda
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They block the receptor
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They activate the receptor
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They destroy the receptor
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They act as inverse agonists
Questão 30
Questão
In which type of hypersensitivity reaction after immune complexes formed?
Questão 31
Questão
Why are immune complexes a problem?
Responda
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Because they can get stuck in the body
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Because they promote autoimmune destruction of cells
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Because they promote other hypersensitivity reactions
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Because they increase the viscosity of blood which can cause thrombosis
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Because they cause lymphadenopathy
Questão 32
Questão
Antibodies in immune complexes can activate complement. True or false?
Questão 33
Questão
What are type IV hypersensitivity reactions mediated by?
Questão 34
Questão
Which of the following are examples of type IV hypersensitivity reactions?
Questão 35
Questão
How do T helper cell cause hypersensitivity reactions?
Responda
-
Cytokine production that activates macrophages and T cytotoxic cells
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Activation of natural killer cells
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Activation of mast cells causing release of histamine
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Formation of immune complexes which activate complement