Chapter 2. Protein Composition and Structure

Descrição

Biochemistry
Amy Arce
Quiz por Amy Arce, atualizado more than 1 year ago
Amy Arce
Criado por Amy Arce aproximadamente 9 anos atrás
33
0

Resumo de Recurso

Questão 1

Questão
What is the function of insulin?
Responda
  • Treat diabetes
  • Protein hormone
  • crucial to maintaining salt levels at appropriate levels
  • crucial to maintaining blood sugar at appropriate levels

Questão 2

Questão
One of the key properties of proteins are?
Responda
  • Proteins are perpendicular polymers composed of amino acids
  • proteins have a wide variety of functional groups
  • Proteins can not interact with one another and other macromolecules to form complexes
  • All proteins are rigid and flexible

Questão 3

Questão
A primary structure is ?
Responda
  • Chains of amino acids in a specific sequence
  • Entire chains fold into well defined structures
  • Amino acids close to one another within a sequence can fold into regular structures
  • Composed of multiple polypeptide chains called subunits

Questão 4

Questão
Alpha helix and beta strands are examples of secondary structures formed by adjacent alpha strands
Responda
  • True
  • False

Questão 5

Questão
Globular proteins such as myoglobin is an example of primary, secondary, tertiary or quaternary structure?
Responda
  • Primary
  • Secondary
  • Tertiary
  • Quaternary

Questão 6

Questão
Hemoglobin is an example of a quaternary structure
Responda
  • True
  • False

Questão 7

Questão
What are the functions of enzymes?
Responda
  • Degrades DNA
  • Degrades RNA
  • Catalyst

Questão 8

Questão
Myofibrils is an example of a protein
Responda
  • True
  • False

Questão 9

Questão
Four classes of amino acids are as followed: [blank_start]Hydrophobic[blank_end] amino acids, [blank_start]Polar[blank_end] amino acids, [blank_start]Positively[blank_end] charged amino acids, and [blank_start]Negatively[blank_end] charged amino acids
Responda
  • Hydrophobic
  • Polar
  • Positively
  • Negatively

Questão 10

Questão
What are the components of an amino acid?
Responda
  • Carbon
  • Nitrogen
  • Carboxylic acid
  • Amino group
  • R group
  • L group

Questão 11

Questão
Only the R isomer is found in proteins
Responda
  • True
  • False

Questão 12

Questão
At neutral pH amino acids primarily exist in the [blank_start]zwitterions[blank_end] form
Responda
  • zwitterions

Questão 13

Questão
Which amino acid is a hydrophobic amino acid?
Responda
  • Glycine
  • Serine
  • Arginine
  • Aspartic Acid

Questão 14

Questão
Positively charged amino acids are
Responda
  • Histidine
  • Tyrosine
  • Leucine
  • Arginine
  • Isoleucine
  • Lysine

Questão 15

Questão
Polar amino acids are
Responda
  • Serine
  • Valine
  • Threonine
  • Tyrosine
  • Glutamine
  • Cysteine
  • Methionine
  • Asparagine

Questão 16

Questão
Negatively charged amino acids consist of [blank_start]Aspartic[blank_end] acid and [blank_start]Glutamic[blank_end] Acid
Responda
  • Aspartic
  • Glutamic

Questão 17

Questão
Phenylalanine, Tryptophan, and Methionine are examples of what amino acid?
Responda
  • Polar
  • Positively charged
  • Hydrophobic
  • Negatively charged

Questão 18

Questão
Glycine, alanine, proline, valine and serine are examples of hydrophobic amino acids
Responda
  • True
  • False

Questão 19

Questão
Peptide bonds are planar
Responda
  • True
  • False

Questão 20

Questão
Amino acids are linked by
Responda
  • peptide bonds to form Polypeptide chains
  • alpha helix
  • beta sheets
  • disulfide bonds

Questão 21

Questão
Most proteins consist of [blank_start]50[blank_end] to [blank_start]2000[blank_end] amino acids
Responda
  • 50
  • 2000

Questão 22

Questão
Polypeptide chain can be cross-linked by sulfide bonds
Responda
  • True
  • False

Questão 23

Questão
Secondary structure
Responda
  • Polypeptide chains that fold into regular structures such as alpha helix, and beta sheet
  • Hemoglobin
  • Myoglobin
  • Chains of amino acids in a specific sequence

Questão 24

Questão
Alpha helix are
Responda
  • Coiled structures stabilized by intracain hydrogen bonds
  • Stabilized by hydrogen bonds between polypeptide strands
  • Not as rod like, fully extended not tightly coiled

Questão 25

Questão
Osteogenesis imperfecta
Responda
  • Defect in collagen, Brittle bone disease occurs if a mutation results in the substitution of another amino acid in place of glycine
  • lack of vitamin C preventing hydroxylation of collagen leading to abnormalities in collagen
  • absence of vitamin K leading to proteins not being carboxylated

Questão 26

Questão
Tertiary structure
Responda
  • Refers to spatial arrangement of amino acids that are far apart in the primary structure and to the pattern of disulfide bond formation
  • Can be as simple as two identical polypeptide chains or as complex as dozens of different polypeptide chains
  • Three-dimensional structure formed by hydrogen bonds between peptide NH and CO groups of amino acids that near one another in the primary structure

Questão 27

Questão
Keratin and collagen are examples of fibrous proteins
Responda
  • True
  • False

Questão 28

Questão
Myoglobin is found within your [blank_start]muscle[blank_end] and [blank_start]binds oxygen[blank_end] on your muscle
Responda
  • muscle
  • binds oxygen

Questão 29

Questão
Quaternary structure
Responda
  • Hemoglobin
  • Globular proteins
  • Spatial arrangement of subunits and their nature of their interaction
  • Spatial arrangement of amino acids that are far apart in the primary structure
  • Structure assemble with other chains to form arrays such as the complex of six insulin molecules
  • Myoglobin

Questão 30

Questão
Hemoglobin is an example of tertiary structure?
Responda
  • True
  • False

Questão 31

Questão
Proteins can be denatured by any treatment that disrupts the weak bonds stabilizing tertiary structure such as
Responda
  • Heating
  • Denaturants

Questão 32

Questão
Scurvy is an example of a disease that results from dysfunctional protein modification and is due to?
Responda
  • Lack of vitamin D which prevents hydroxylation of collagen
  • Lack of vitamin C which prevents hydroxylation of collagen leading to abnormalities in collagen
  • due to absence of vitamin K leading to clotting proteins not being carboxylated

Questão 33

Questão
Hemorrhaging is due to the absence of vitamin K
Responda
  • True
  • False

Questão 34

Questão
Amyloidoses plaques cause disease such as
Responda
  • Alzheimer's
  • Parkinson's
  • Huntington's
  • HIV
  • Osteogenesis imperfecta
  • Sickle cell

Questão 35

Questão
The function of a promoter is to initiate process or transcription
Responda
  • True
  • False

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