Questão 1
Questão
Aldosterone stimulates the reabsorption of water in the nephron via which process?
Responda
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Synthesis of glucose channels
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Increasing the flow of filtrate
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Upregulation of epithelial sodium channels
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Excretion of water
Questão 2
Questão
Which of the following produce antibodies
Responda
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Erythrocytes
-
T lymphocytes
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B lymphocytes
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Thrombocytes
Questão 3
Questão
which of the following provides the correct definition of cor pulmonale
Responda
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abnormal enlargement of the right side of the heart as a result of diesease of the lungs or the pulmonary blood vessels
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abnormal enlaregemnt of the left side of the heart as a resukt of disease of the lungs or the pulmonary blood vessels
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abnormal enlargement of the right side of the heart as a resukt of an increase in systemic afterload
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abnormal enlargement of the left side of the heart as a result of an increase in right sided afterload
Questão 4
Questão
During myocyte depolarisation this outside of the cell become:
Responda
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positive
-
negative
-
stays the same
-
become hyperpolerized
Questão 5
Questão
What is the source of energy used to power the sodium-potassium pump?
Questão 6
Questão
which of the following is true?
Responda
-
In systolic heart failure the heart’s ejection fraction increases
-
In systolic heart failure the heart’s ejection fraction stays the same
-
In systolic heart failure the heart’s ejection fraction decreases
-
In diastolic heart failure the ejection fraction increases
Questão 7
Questão
During myocardial diastole the sodium / potassium pump:
Responda
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Pumps out 3 sodium ion and pump in 2 potassium ions
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Pumps out 6 sodium ions and pumps in 4 potassium ions
-
Pumps in 3 sodium ions and pumps out 2 potassium ions
-
Pumps in 6 sodium ions and pumps out 4 potassium ions
Questão 8
Questão
Which of the following types of emphysema is most commonly associated with smoking and chronic bronchitis
Responda
-
Paraseptal
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Panacinar
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Centriacinar
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Irregular
Questão 9
Responda
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is composed of four identical subunits
-
has iron at the centre of haem groups which must be in the ferrous form to bind O2
-
binding of oxygen is reduced in the presence of high Pco2 because CO2 and O2 compete for the same binding sites on haemoglobin
-
variants (such as fetal haemoglobin) often differ from normal adult haemoglobin in the precise structure of the haem group.
Questão 10
Questão
Which of the following is a neurotransmitter in the sympathetic nervous system?
Responda
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Acetylcholine
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Norepinephrine
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Vasopressin
-
Enoximone
Questão 11
Questão
The alveolar pores that enable collateral ventilation are called:
Responda
-
Pores of Oddi
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Pores of Kohn
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Pores of Dalton
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Pores of Boyles
Questão 12
Questão
Peripheral chemoreceptors are highly responsive to:
Responda
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Dysponea
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Coughing
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Hypoxemia
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Breath holding
Questão 13
Questão
Aspirin is given in the treatment of myocardial infarction in order to prevent platelet aggregation. Which of the following effects means it is useful in this situation?
Questão 14
Questão
During myocyte (heart cell) depolarisation, the inside of the cell becomes momentarily:
Responda
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positive
-
negative
-
electrically neutral
-
unchanged
Questão 15
Questão
The Law stating that the more the ventricle is filled with blood during diastole (end-diastolic volume), the greater the volume of ejected blood will be during the resulting systolic contraction (stroke volume) is the:
Responda
-
Frank-Starling’s Law
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Cushing’s Law
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Virchow’s triad Law
-
Best-Banting Law
Questão 16
Questão
The anaerobic metabolism of carbohydrates results in the production of:
Responda
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Citric acids
-
keto acids
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lactic acid
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hydrochloric acid
Questão 17
Questão
Flattened T waves on an ECG can signify:
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1st Degree heart block
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Hyperkaleamia
-
Hypokaleamia
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Atrial fibrillation
Questão 18
Questão
The diuretic Spironolactone interferes with the action of which endogenous hormone?
Questão 19
Questão
During acidosis the pH scale moves
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up
-
down
-
stays the same
-
moves to one
Questão 20
Questão
A disease caused by the demyelination of the oligodendrocytes
Questão 21
Questão
Intra-plural pressure is:
Questão 22
Questão
Concerning fats, when triglyceride molecules contain only single carbon bonds (c-c-c) these are referred to as:
Responda
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Poly unsaturated fats
-
saturated fats
-
Hyper-carbonated fats
-
Mono unsaturated
Questão 23
Questão
With a nasal cannula in-situ @ 2L O2 what % increase in FiO2 will there be
Questão 24
Questão
Which of the following is a restrictive lung disease:
Responda
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Asthma
-
Pneumoconiosis
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Emphysema
-
Chronic bronchitis
Questão 25
Questão
Heart failure results in which of the following type of hypoxia
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Anaemic hypoxia
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Histo-toxic
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Hypoxic
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Stagnant
Questão 26
Questão
Type II pneumocytes in the lung are the major source of
Responda
-
IgG
-
cytokines
-
oxygen
-
surfactant proteins (SP)
Questão 27
Questão
A reduction in lung compliance would lead to a
Questão 28
Questão
Which lung volume would (usually) be reduced in restrictive lung disease
Responda
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Inspiratory reserve volume
-
Function residual capacity
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Residual volume reserve
-
Expiratory reserve volume
Questão 29
Questão
If the fraction of an inspired gas was .35 what would its partial pressure be at 1ATM
Responda
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210mmHg
-
160mmHg
-
350mmHg
-
266mmHg
Questão 30
Questão
E = P + pgh + ½ PV2 which, if we remove gravity, reads as E = P + ½ PV2. Or, more simply, the faster the flow, the lower the pressure is which theorem
Responda
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Venturi’s
-
Dalton’s
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Bernoulli’s
-
Charles’s
Questão 31
Questão
Hypocalcaemia caused by hyperventilation results in which of the following signs
Responda
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Dahl’s sign
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Palmar erythema
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Trousseau sign
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Schamroth's sign
Questão 32
Questão
Replacing inspired air with a gas mixture that contains 60% oxygen
Responda
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causes a large increase in oxygen content with little increase in oxygen saturation in a healthy person at high altitude
-
causes a large increase in arterial PaO2 and a small increase in oxygen content in a healthy person at sea level
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would greatly enhance the exercise tolerance of a patient COPD
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would greatly reduce the oxygen delivery problems of a patient in circulatory shock
Questão 33
Questão
Antidiuretic hormone (ADH) is secreted by
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Adrenal glands
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Kidneys
-
Pineal gland
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Hypothalamus
Questão 34
Questão
Macula densa cells help regulate blood pressure by detecting changes to
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Sodium
-
Potassium
-
oxygen
-
calcium
Questão 35
Questão
Which of the following anatomical portion of a nephron connects the Bowman’s capsule to the loop of Henle?
Questão 36
Questão
The gene responsible for causing Duchenne muscular dystrophy is found on
Questão 37
Questão
Which of the following is the primary neurotransmitter of the parasympathetic nervous system
Responda
-
Adrenaline
-
Acetylcholine
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Dopamine
-
Serotonin
Questão 38
Questão
Which of the following heart layers secretes pericardial fluid?
Responda
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Myocardium
-
Endocardium
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Serous pericardium
-
Fibbrous pericardium
Questão 39
Questão
The Haldane effect states that
Responda
-
for any given Pco2 less CO2 is carried by oxygenated blood
-
an increase in Pco2 shifts the O2 dissociation curve to the left
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an increase in Pco2 reduces the amount of haemoglobin in the red cell.
-
for any given Pco2 more CO2 is carried by oxygenated blood
Questão 40
Questão
Ventilation is NOT increased by
Questão 41
Questão
The amount of a gas dissolved in a solution as a result of partial pressure is which of the following gas laws
Responda
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dalton
-
henrys
-
charles
-
boyles
Questão 42
Questão
How is the ejection fraction worked-out
Responda
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SV/EDV x 100
-
EDVEDV/SV x 100
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RVEDV x EDV x 100
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EDV/100 x 60
Questão 43
Questão
The layer of blood close to the walls of lung capillaries is known as the
Responda
-
RBC layer
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Tissue barrier layer
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Alveolar fluid layer
-
plasma layer
Questão 44
Questão
A pulmonary embolism would result in
Questão 45
Questão
The rate of diffusion of a gas across a membrane is inversely proportional to the square root of its molecular weight - is a definition of which of the following gas laws
Responda
-
ficks law
-
daltons law
-
grahams law
-
chales law
Questão 46
Questão
Angiotensin I is converted to angiotensin II in the:
Responda
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lungs
-
nephron
-
pancreas
-
bowman's capsule
Questão 47
Questão
Hydrostatic pressure at the venule end of a capillary is usually (approximately)
Responda
-
25mmHg (3.3kPa)
-
32mmHhg (4.2kPa)
-
80mmHg (10.6kPa)
-
12mmhg (1.6Pa)
Questão 48
Questão
A symptom seen in the patient with Keto-acidosis
Responda
-
Bradycardia
-
Keto-alkalosis
-
kussmaul respiration
-
Bradyapnoea
Questão 49
Questão
During DKA sodium bicarbonate levels are:
Responda
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raised
-
lowered
-
absent
-
normal
Questão 50
Questão
Which of the following will increase the stroke volume:
Responda
-
Decreased venous return
-
Increased afterload
-
Decreased preload
-
Increased venous return
Questão 51
Questão
The renal system does not play a direct role in regulating which of the following
Questão 52
Questão
Angiotensin II exerts its action by binding to various receptors throughout the body. In response to angiotensin II, the adrenal cortex is stimulated to release
Responda
-
Adrenaline
-
Angiotensin I
-
Angiotensin ll
-
Aldosterone
Questão 53
Questão
Most of the glucose that is filtered through the glomerulus undergoes reabsorption in the
Questão 54
Questão
Which is not a function of angiotensin ll
Questão 55
Questão
Which is not a sign of renal cell carcinoma
Responda
-
Flank pain
-
Flank mass
-
Heamaturia
-
Cullen's sign
Questão 56
Questão
Aldosterone stimulates the reabsorption of water in the nephron via which process
Responda
-
Synthesis of glucose channels
-
Increasing the flow of filtrate
-
Excretion of water
-
Upregulation of epithelial sodium channels
Questão 57
Questão
The majority of carbon dioxide produced by the body is transported
Questão 58
Questão
Von Hippel-Lindau syndrome is
Questão 59
Questão
4)The first stage of the RAAS is the release of angiotensinogen, which is produced (primarily)
Responda
-
Carotid arch
-
Brain
-
Lungs
-
Liver
Questão 60
Questão
Insufficiency of ADH is a condition called
Responda
-
Addison's disease
-
Renal disease
-
Cushing's disease
-
Diabetes insipidus
Questão 61
Questão
Antidiuretic hormone (ADH) is secreted by
Responda
-
Kidneys
-
Adrenal glands
-
Hypothalamus
-
Pineal gland
Questão 62
Questão
In the adult the majority
Responda
-
Basophils
-
Eosinophils
-
Lymphocytes
-
Neutrophils
Questão 63
Questão
Macula densa cells are chemoreceptors found in the
Responda
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Distal tubule
-
Proximal tubule
-
Descending loop of Henle
-
Ascending loop of Henle
Questão 64
Questão
The amount of air that is moved in and out of the lungs during normal quiet breathing is
Questão 65
Questão
increase in the partial pressure of carbon dioxide favours oxygen dissociation from
oxyHb. The effect is known as
Responda
-
The Nernst effect
-
The Bohr effect
-
Henderson effect
-
Dalton effect
Questão 66
Questão
The Hering-Breuer reflex
Responda
-
Inhibits expiration
-
prolongs inspiration time
-
Shortens inspiration time
-
Is initiated by expiration
Questão 67
Questão
Which definition best suits the term 'inflammation' in relation to asthma
Responda
-
Inflammation is caused by infectious agents in asthma, and is mediated by antiproteases
-
Inflammation is associated with airway remodelling in asthma. Inflammation is triggered by a stimulus, and causes epithelial injury, among other things
-
Mast cells can help to reduce inflammation by releasing histamine and preventing further lung damage
-
Inflammation is caused by airway remodelling in asthma.
Questão 68
Questão
Interstitial fluid enters capillaries at the venular end through the action of
Responda
-
Negative pressure
-
Colloid osmotic pressure
-
Active transport
-
Capillary co-transport
Questão 69
Questão
What are the classic signs of a cardiac tamponade
Responda
-
Tachycardia, dyspnoea, fever
-
Bradycardia, arm weakness, diaphoresis
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Hypertension, palpitations, chest pain
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Hypotension, increased jugular venous distention, muffled heart sounds
Questão 70
Questão
The term 'ectopic pacemaker' (or ectopic focus)
Responda
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An ectopic arrythmia due to hyponatraemia
-
Any cardiac dysrhythmia
-
A shift of the pacemaker function of the SA node to another part of the heart
-
An arrythmia due to hyper
Questão 71
Questão
In cor pulmonale the
Responda
-
the mean pulmonary arterial pressure increases
-
the mean arterial pressure decreases
-
the mean pulmo
-
the mean pulmonary arterial pressure is 10mmhg
Questão 72
Questão
a person who smoked 20 cigarettes a day for 30 years has a pack years of
Questão 73
Questão
which of the following types of emphysema is most commonly asscoiated with smoking and chronic bronchitis
Responda
-
paraseptal
-
panacinar
-
centaicinar
-
irregular
Questão 74
Questão
a patients blood gas analysis shows that both their Paco2 and bicarbnate concentration are increased above normal by 25% what does this mean ?
Responda
-
They are excercising and so producing more CO2
-
The arterial Ph is unchanged
-
They are likely to have renal damage
-
They are likely to be polycythaemic
Questão 75
Questão
Which of the following is not normally associated with chironic bronchitis
Questão 76
Questão
Urine is formed in a three step process, which of the follwoing gives the correct order in which these steps take place in the nephron
Responda
-
Tubular secretion, tubular re-absorption, glomerular filtration
-
Tubular reabsorption, tubular secretion, glomerular filtration
-
Glomerular filtration, tubular reabsorption, tubular secretion
-
glomerular filtration, tubular secretion, tubular reabsorption
Questão 77
Questão
Which of the following is least likely to be present in the gfiltrate, (the filtrate produced by the nephron before it enters the loop of henle) of a healthy adult nnephron
Questão 78
Questão
Which of the following is not a function of aldosterone
Responda
-
Stimulates the secretion of K+ into the tubular lumen
-
Stimulates Na+ and water reabsorption
-
Upregulates epithelial sodium channels
-
Causes vasodilation
Questão 79
Questão
Which of the following produces surfactant
Responda
-
Type 1 pneumocytes
-
Type 2 pneumocytes
-
Oligodendrocytes
-
Schwann cells
Questão 80
Questão
Which of the following is NOT a restrictive lung disease
Responda
-
pneumoconiosis
-
Silcosis
-
Tuberculosis
-
Asthma
Questão 81
Questão
The enzyme that assists rapid inter conversion of carbon dioxide and water into carbonic acid is
Responda
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Amylase
-
Lipase
-
Trypsin
-
Carbonic anhydrase
Questão 82
Questão
The (normal) intra-venous partial pressure of carbon dioxide is
Responda
-
40 mmHg
-
55mmHg
-
46mmHg
-
35mmHg
Questão 83
Questão
Which of the following is NOT found in the service side of type 1 pneumocytes
Responda
-
nerve endings
-
macrophages
-
Collagen
-
Surfactant
Questão 84
Questão
Within the cerebral spinal space and the CSF what regulates ventilation
Responda
-
carbon dioxide
-
carbonic anhydrase
-
Hydrogen ions
-
carbonic acid
Questão 85
Questão
Carbon dioxide is how many times more soluble than oxygen
Responda
-
10 times
-
20 times
-
100 times
-
40 times
Questão 86
Questão
With a nasal cannula, we assume that the fraction of O2 that is inspired (above the normal atmospheric level) increases by how much for every additional litre of oxygen flow administered
Responda
-
10 percentage points
-
100 percentage points
-
4 percentage points
-
21 percentage points
Questão 87
Questão
Which of the following does NOT contribute to maintaining osmotic pressure
Responda
-
Sodium
-
Glucose
-
Albumin
-
Calcium
Questão 88
Questão
A respiratory acidosis moves the O2 curve and the PH respectfully
Responda
-
Right/down
-
Left/up
-
Right/up
-
left/down
Questão 89
Questão
the protein whose production gets affected in Duchenne muscukar dystrophy is
Responda
-
actin
-
myotropin
-
dystropin
-
leucovorin
Questão 90
Questão
Duchenne muscular dystrophy can be cured with
Questão 91
Questão
The involvement of this muscle affects the breathing in duchenne muscular dystrophy
Responda
-
triceps
-
biceps
-
diaphragm
-
quadriceps
Questão 92
Questão
Which of the following represents one of the most recent developments in the treatment of MD
Questão 93
Questão
SLUDGE syndrome stands for which of the following
Responda
-
Salvation, lacrimation, urination, defacation, gastrointestinal symptoms and emesis
-
sodium retention, lactic acidosis, urine retention, deafness, gastrointestinal bleeding and episodes of dizzines
-
Scoliosis, limited movement, urinary failure, decay, gastrointestinal ulceration, and epilepsy
-
sepsis, lymphedema, ulceration, diabetes, genital warts and Ecoli infection
Questão 94
Questão
Which portion of the heart is the base and which sis the apex
Responda
-
Two thirds apex and one third base
-
one third base, two thirds apex
-
one half base, one half apex
-
three quaters base and one quater apex
Questão 95
Questão
Which of the following factors increase cardiac output
Questão 96
Questão
Where is the stethoscope (best) placed to auscultate the mitral valve
Responda
-
5th intercostal space at sternum
-
5th intercostal space inferior to left nipple
-
2nd intercostal space left of sternum
-
2nd intercostal space right of sternum
Questão 97
Questão
On the ECG the short flat segment between the S and T waves represents the refractory state of the
Responda
-
Atrial myocardium
-
AV node
-
SA node
-
Ventricular myocardium
Questão 98
Questão
Considering cardiac tamponade - the heart is covered by
Responda
-
pericardium
-
endocardium
-
epicardium
-
supracradium
Questão 99
Questão
Which of the following is isotonic
Responda
-
0.9% saline
-
water
-
5% dextrose
-
Lucozade
Questão 100
Questão
Fenestrated capillaries are found in the
Responda
-
muscles
-
adipose tissue
-
central nervous system
-
intestines
Questão 101
Questão
Which of the following would be the best initial management of an acute cardiac tamponade
Questão 102
Questão
which of the following is not a structure of the respiratory system
Responda
-
pharynx
-
larynx
-
bronchus
-
hyoid
Questão 103
Questão
the roof of the nasal cavity is formed primarily by the
Responda
-
cribriform plate
-
hard palate
-
superior concha
-
sphenoid
Questão 104
Questão
in the blood most of the carbon doixide is transported as
Responda
-
carboxyhaemoglobin
-
dissolved carbon dioxide
-
as free hydrogen
-
as bicarbonate
Questão 105
Questão
peripheral chemoreceptors are located in
Responda
-
lung tissue
-
pons and medulla
-
aortic & carotid bodies
-
renal arch
Questão 106
Questão
Factors determining the extent to which oxygen will combine with haemoglobin include
Responda
-
partial pressure oxygen
-
blood temperature
-
blood PH
-
all of the above
Questão 107
Questão
expectorate in uncomplicated asthma has a high level of
Responda
-
neutrophils
-
eosinophils
-
red blood cells
-
IgD
Questão 108
Questão
Which of the following is not a classic clinical characteristic of asthma
Responda
-
dyspnoea
-
wheeze
-
cough
-
Increased FEV1
Questão 109
Questão
In the adult the majority of leukocytes are
Responda
-
basophils
-
eosinophils
-
lymphocytes
-
neutrophils