451493
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
quase 11 anos atrás
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Questão 1
Questão
What is the main problem of protein translocation?
Responda
-
Hydrophillic proteins must transverse two hydrophobic membranes and a hydrophillic space
-
Proteins must be unfolded and refolded again
-
Proteins must pass through an extremely crowded cytoplasm
Questão 2
Questão
Proteins to be secreted directly after translation have a peptidase sequence at the C-terminus
Responda
- True
- False
Questão 3
Questão
Which of the following parts of the peptidase sequence are closest to the N-terminus?
Responda
-
The basic residues
-
The hydrophobic region
-
Peptidase cleavage recognition site
Questão 4
Questão
There are 1-2 basic residues in the signal sequence, but the hydrophobic sequence is variable in length
Responda
- True
- False
Questão 5
Questão
When a protein is transcribed with the Peptidase signal site, what protein binds to its hydrophobic region?
Responda
-
Signal Recognition Protein
-
Ftsy- a GTPase
-
SecYEG- a bacterial pore
Questão 6
Questão
Ftsy transfers the protein into the pore
Responda
- True
- False
Questão 7
Questão
Which of the following provide the driving force for protein translocation across the membrane
Responda
-
Protonmotive force
-
FtsY's GTPase
-
Protein translation
Questão 8
Questão
What binds to the nascent polypeptide if Post-Translational Translocation takes place?
Responda
-
SecB
-
SecA
-
SecC
Questão 9
Questão
Post-Translational Translocation sequences have a string of hydrophobic amino acids, same as in Translational Translocation
Responda
- True
- False
Questão 10
Questão
What is the role of Sec_ ?
Responda
-
To keep the protein in solution till it binds to SecA at the pore
-
To fold the protein on its way to the periplasmic more
-
To stop the protein folding on its way to SecC
Questão 11
Questão
What forces are required to get a Post-Translational Translocation through the pore?
Responda
-
GTPase of FtsY
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ATP hydrolysis by SecB
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Protonmotive Force
Questão 12
Questão
Once inside the required membrane, what protein removes the peptide sequence?
Responda
-
Signal peptidase
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Signal lyase
-
Signal Isomerase
Questão 13
Questão
The protein only folds after the signal sequence is cleaved
Responda
- True
- False
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