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454588
Linkage Analysis
Descrição
Year 2 Quiz sobre Linkage Analysis, criado por gina_evans0312 em 26-12-2013.
Sem etiquetas
disease pedigrees
genetics and genomics
year 2
Quiz por
gina_evans0312
, atualizado more than 1 year ago
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Criado por
gina_evans0312
quase 11 anos atrás
613
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Resumo de Recurso
Questão 1
Questão
Metaphase is the most important stage for genetic mapping
Responda
True
False
Questão 2
Questão
Recombination cannot be detected in...
Responda
Homozygotes
Heterozygotes
Because both alleles are different
Because both alleles are identical
Questão 3
Questão
What indicates linkage?
Responda
The no of recombinants
The no of homozygotes
The no of heterozygotes
Questão 4
Questão
A generation bred from parents AB & ab, has 1 recombinant out of 20- is linkage involved
Responda
Yes
No
Questão 5
Questão
Recombinant detecting probes can be fooled if double recombination occurs
Responda
True
False
Questão 6
Questão
Which of the following gametes tend to recombine more around the centromere?
Responda
Spermatocytes
Oocytes
Questão 7
Questão
Oocytes tend to recombine
Responda
Around the telomeres
Around the centromere
More than spermatocytes
Less than spermatocytes
Questão 8
Questão
Most recombination occurs at random
Responda
True
False
Questão 9
Questão
What is 1q42.3 referring to?
Responda
Short arm of chromosome 1
Long arm of chromosome 1
Locus position (from telomere to centromere)
Locus position (from centromere to telomere)
Questão 10
Questão
Meiosis is made informative or uninformative depending on whether you can track the diseased allele
Responda
True
False
Questão 11
Questão
What must be known for effective meosic analysis?
Responda
Grandparent -> Grandchild phenotype
Grandchild & all siblings phenotype
Parent & all siblings -> Grandchild phenotype
Questão 12
Questão
Is the following informative for linkage analysis?
Image:
Non-Informative (image/png)
Responda
Yes- the child is a recombinant
No- the child is heterozygous
No- the father is homozygous
Questão 13
Questão
How would you classify this?
Image:
Informative_Non-Recombinant (image/png)
Responda
Uninformative non-recombinant
Informative recombinant
Informative Non-recombinant
Questão 14
Questão
This is an informative recombinant
Image:
Informative_Recombinant (image/png)
Responda
True
False
Questão 15
Questão
What is true of Recombinant/Human Pedigree Analysis?
Responda
The lower the recombination frequency, the more likely the hypothysis is to be correct
The higher the recombination frequency, the more likely the hypothysis is to be correct
Questão 16
Questão
A mother has a disease, and has the alleles M1 & M2- what are the two hypothesis for pedigree analysis?
Responda
M1 is diseased M2 is healthy
M1 is healthy M2 is diseased
M1 & M2 are healthy
M1 & M2 are diseased
Questão 17
Questão
Give the two Recombination frequencies for that above image
Image:
Recombinant_Analysis (image/png)
Responda
0.16 & 0.83
1.66 & 8.33
16.66 & 83.33
Questão 18
Questão
A higher recombination frequency means alleles are closer together
Responda
True
False
Questão 19
Questão
Define a Marker
Responda
Any mendelian character that can be used to follow a disease through a pedigree
A fluorescent dye used to find particular alleles
A mutagen used to create findable mutations
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