454649
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
aproximadamente 11 anos atrás
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Questão 1
Questão
What does genetic mapping rely on?
Responda
-
Inheritence phenotypes
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Polymorphic Markers
Questão 2
Questão
How is the tracing of inheritence phenotypes done?
Responda
-
Genetic markers i.e. SNP's
-
Allele complimentation
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Meiotic Tests
Questão 3
Questão
1cM =
Responda
-
1% recombination
-
10% recombination
-
1kB
-
10kB
Questão 4
Questão
How are physical maps made?
Responda
-
Design markers that overlap along the genome
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Orientation of homologous chromosomes
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Allele studies
Questão 5
Questão
Physical maps must be made of physically isolated parts of the genome
Responda
- True
- False
Questão 6
Questão
A genetic marker acts as a reference point in a linkage study
Responda
- True
- False
Questão 7
Questão
Genes are usually used as markers in non-human studies. Why can they not be used in humans?
Responda
-
Human genes are more unstable
-
Human genes vary too much
-
Human genes are more highly conserved
Questão 8
Questão
What is the preferred form of marker in humans?
Responda
-
Polymorphic introns
-
Polymorphic Exons
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SNP's
Questão 9
Questão
More polymorphic DNA= less useful
Responda
- True
- False
Questão 10
Questão
Homozygotes are more useful in genetic mapping than heterozygotes
Responda
- True
- False
Questão 11
Questão
How must markers be placed along the chromosome?
Responda
-
Evenly spaced
-
As lightly as possibly
-
As densely as possible
Questão 12
Questão
The aim it to combine genetic and physical maps
Responda
- True
- False
Questão 13
Questão
Once you have a marker with a high linkage to a disease/trait, how do you use the physical map?
Responda
-
Find the marker and look for genes very close to it
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Find the suspect gene and look for markers very close to it
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Find the marker and look for genes as far away as possible
Questão 14
Questão
Which of the following are evenly distributed?
Responda
-
SNP's
-
Minisatellites
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Microsatellites
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RFLP's
Questão 15
Questão
Microsatellites are highly polymorphic
Responda
- True
- False
Questão 16
Questão
Which of the following are most useful as markers?
Responda
-
RFLP's
-
Minisatellites
-
Microsetellites
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SNP's
Questão 17
Questão
There are two alleles (usually) for RFLP's
Responda
- True
- False
Questão 18
Questão
How are minisatellites typed?
Responda
-
Southern Hybridisation
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Gel Electrophoresis
-
PCR
Questão 19
Questão
There are more than 10^10 SNP's in the human genome
Responda
- True
- False
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