456208
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
quase 11 anos atrás
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Questão 1
Questão
How does a retroviruse reproduce?
Responda
-
Nuclear fission
-
Reverse transcription onto host genome
-
Binary fission
Questão 2
Questão
Reverse Transcriptase is vital for RNA retroviruses to replicate
Responda
- True
- False
Questão 3
Questão
The viral protein P is used for what?
Responda
-
Packaging signal for making virus particles
-
Capsid protein
-
For genome expression
Questão 4
Questão
Gag is the gene for envelope proteins
Responda
- True
- False
Questão 5
Questão
Which of the following can be directly translated?
Responda
-
+ve sense RNA
-
-ve sense RNA
Questão 6
Questão
What protein converts viral genomes into a version host cells can transcribe?
Responda
-
RNA dependent RNA polymerase
-
DNA dependent RNA polymerase
-
DNA dependent DNA polymerase
-
RNA dependent DNA polymerase
Questão 7
Questão
The Transcriptosome is the cell repetoire of proteins
Responda
- True
- False
Questão 8
Questão
What is the role of enhancers?
Responda
-
To make proteins more efficient
-
To make transcription of a gene more likely
-
To increase cell division
Questão 9
Questão
Name the types of enhances possible
Responda
-
Upstream
-
Adjactent
-
Downstream
-
Internal
Questão 10
Questão
Introns can make up to 2% of the gene
Responda
- True
- False
Questão 11
Questão
Assuming the middle segment is an intron, what is found at the 5' and 3' splice sites of the intron?
Image:
Splicing (image/png)
Responda
-
3'- G-T 5'- Pyrimidine tract
-
5' - G-U 3' - Pyrimidine tract & A-G
-
5' - Pyrimidine tract & A-T 3' G-A
Questão 12
Questão
How is the 5' intron splice site cleaved?
Responda
-
Hydroxyl attack by an adenine
-
Hydroxyl attack by a pyrimidine from the 5' exon splice site
-
The 5' exon splice site attacks the 3' intron splice site
Questão 13
Questão
The 5' is cleaved and the intron loops on itself- what removes the intron totally?
Responda
-
The 5' exon attacks the 3' splice site
-
The 3' exon attacks the 5' splice site
-
The 3' exon attacks itself
Questão 14
Questão
What is the roles of snRNA?
Responda
-
Help for splicosome
-
Resist formation of the splicosome
-
Remove intron after splicing
Questão 15
Questão
Twintrons are introns within introns
Responda
- True
- False
Questão 16
Questão
Which is spliced out first?
Responda
-
Introns
-
Twintrons
Questão 17
Questão
GpG islands are found near transcriptionally inactive human genes
Responda
- True
- False
Questão 18
Questão
Name the two theories concerning introns
Responda
-
Introns are ancient and are gradually being lost
-
Introns are new and are gradually being accumulated
Questão 19
Questão
What does snoRNA stand for?
Responda
-
Small nuclear RNA
-
Small nullifying RNA
-
Small nucleolear RNA
Questão 20
Questão
snoRNA causes RNA to be acetylated
Responda
- True
- False
Questão 21
Questão
SnoRNA binds to the RNA to be modified
Responda
- True
- False
Questão 22
Questão
What can SnoRNA binding lead to?
Responda
-
The modification of bases
-
The destruction of the mRNA
-
The replication of the mRNA
Questão 23
Questão
There are few miRNA's, but they are very large
Responda
- True
- False
Questão 24
Questão
What is the role of miRNA
Responda
-
mRNA silencing
-
Prevent mRNA degredation
-
Inhibit transcription
Questão 25
Questão
Once the miRNA is transcribed, what structures form?
Responda
-
Cruciforms
-
Holliday junctions
-
Stem-loop junctions
Questão 26
Questão
What enzyme have these miRNA precursors NOT been cut by?
Image:
miRNA_Precursors (image/png)
Responda
-
Drosher
-
Dicer
Questão 27
Responda
-
Binds to 5' end of mRNA to prevent ribosome binding
-
Bind to region between polyA tail and gene, causing cleavage of polyA tail
-
Bind in centre and cause mRNA looping
Questão 28
Questão
siRNA stands for Short Interfering RNA
Responda
- True
- False
Questão 29
Questão
What is the main role of siRNA?
Responda
-
Protection against RNA viruses
-
Protection against oncogenes
-
Protection against bacteria
Questão 30
Questão
Where and to what does siRNA bind?
Responda
-
mRNA of viral genome
-
mRNA of bacterial genome
-
mRNA of human genome
-
On transcribing region
-
On poly-A tail
Questão 31
Questão
siRNA binds to mRNA in a double stranded form
Responda
- True
- False
Questão 32
Questão
Which of the following could be used as a gene therapy?
Responda
-
miRNA
-
siRNA
-
snRNA
-
snoRNA
Questão 33
Questão
This RNA gene therapy works by making a dsRNA version of a gene in the cell; this will be cleaved to siRNA which will destroy ALL mRNA for that gene
Responda
- True
- False
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