5652920
Descrição
Quiz por Med Student , atualizado more than 1 year ago
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Criado por Med Student
mais de 8 anos atrás
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Questão 1
Questão
A blood group has both A and B antigens but no antibodies, It is
Responda
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B
-
AB
-
O
-
A
Questão 2
Questão
A compound formed in an organism for inhibiting growth of another organism is
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Antigen
-
Antibody
-
Antibiotic
-
Antiallergic
Questão 3
Questão
A disease due to allergic reaction is
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Enteric fever
-
Yellow fever
-
Hay fever
-
Trench fever
Questão 4
Questão
Which is involved in body defense?
Responda
-
Neutrophils
-
Macrophages
-
Lymphocytes
-
All the above
Questão 5
Questão
A doctor suggested to a couple not to have more than one child because of
Responda
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Rh+ male Rh- female
-
Rh- male Rh+ female
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Rh+ male Rh+ female
-
Rh- male Rh- female
Questão 6
Questão
A molecule that produces an immune response is
Responda
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Antigen
-
Antibody
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Carcinogen
-
Mutagen
Questão 7
Questão
A noninfectious unnatural and unusual reaction to a substance or condition is
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Immunity
-
Allergy
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Infection
-
Toxin
Questão 8
Questão
A person is injected with gammaglobulin against hepatitis B. It is
Responda
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Artificially acquires passive immunity
-
Artificially acquires active immunity
-
Naturally acquires active immunity
-
Naturally acquires passive immunity
Questão 9
Questão
Acquired immunity as developed after vaccination or infection is found in
Responda
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Vertebrates only
-
Invertebrates as well as vertebrates
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Plants
-
All the above
Questão 10
Questão
Acquired immunity is found in
Responda
-
Invertebrates
-
Vertebrates
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Some invertebrates
-
Both vertebrates and invertibrates
Questão 11
Questão
Active immunity is due to
Responda
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Suppressor T-cells
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killer T-cells
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Memory cells
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Helper T-cells
Questão 12
Questão
Active immunity means
Responda
-
Resistance developed before disease
-
Resistance developed after disease
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Increased heart beat
-
Increased flow of blood
Questão 13
Questão
AIDS is caused by
Responda
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RNA virus
-
DNA virus
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Herpes virus
-
Hepatitis virus
Questão 14
Questão
An example of innate immunity is
Responda
-
T-lymphocytes
-
B-lymphocyte
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Neutrophils
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Thyroid cells
Questão 15
Questão
An insect bite may result in inflammation of that spot. It is triggered by alarm chemicals such as
Responda
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Histamine and dopamine
-
Histamine and kinins
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Interferon and opsonin
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Interferons and histones
Questão 16
Questão
An Rh- individual receives Rh+ blood. The recipient becomes
Responda
-
Sterlite
-
Dead
-
No reaction
-
Isoimmunised
Questão 17
Questão
Which of the following are secondary lymphoid organs?
Responda
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Spleen
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Lymph Nodes
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Thymus
-
Bone Marrow
-
Lymph Vessels
Questão 18
Questão
IgG consists of
Responda
-
2 light chains and two heavy chains joined by di-sulphide bond (H2L2)
-
2 light chains and two heavy chains joined by hydrogen bond (H2L2)
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2 light chains and a heavy chain joined by di-sulphide bond (H1L2)
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a light chain and two heavy chains joined by di-sulphide bond (H2L1)
Questão 19
Questão
Which is the Ig that first reaches the site of infection?
Responda
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IgM
-
IgG
-
IgA
-
IgE
Questão 20
Questão
Which is the largest Ig?
Responda
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IgM
-
IgG
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IgA
-
IgE
Questão 21
Questão
Which of the following statements are true regarding IgM?
Responda
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IgM is a pentamer and is the largest Ig and called as ‘natural antibody’
-
IgM exists as monomer on B-cell surface
-
IgM is involved in early primary immune response
-
all of these
Questão 22
Questão
Which of the following statements are true?
Responda
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IgM is involved in primary immune response
-
IgG is involved in primary immune response
-
Both IgM and IgG are involved in primary immune response
-
IgG is involved only in secondary immune response
Questão 23
Questão
The antibody present in secretions like tears, saliva, colostrum is
Responda
-
IgM
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IgG
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IgA
-
IgE
Questão 24
Questão
The primary Ig of exocrine secretions is
Responda
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IgM
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IgG
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IgA
-
IgE
Questão 25
Questão
Antibodies are:
Responda
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proteins
-
glycoproteins
-
carbohydrates
-
nucleic acid
Questão 26
Questão
The antigen binding site on an antibody is called:
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endotope
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paratope
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epitope
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antitope
Questão 27
Questão
An antibody has
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2 Fab regions and an Fc region
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an Fab region and an Fc region
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2 Fab regions and 2 Fc regions
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many Fab regions and many Fc regions
Questão 28
Questão
The hypervariable region resides in the
Responda
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N terminal region of light chain
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N-terminal region of light and heavy chain
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C-terminal region of light chain
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C-terminal region of light chain and heavy chain
Questão 29
Questão
Fab stands for
Responda
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fragment antibody binding
-
fragment antigen binding
-
fragment antibody or antigen binding
-
fragment affinity binding
Questão 30
Questão
Which of the following statement is true regarding Fc region?
Responda
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fragment crystalisation and is the constant region
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fragment constant and is the variable region
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fragment crystalisation and is the variable region
-
fragment crystalisation and has both variable and constant region
Questão 31
Questão
Fab region:
Responda
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has a hypervariable region that binds with antibody
-
has a hypervariable region that binds with antigen
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has a hypervariable region that binds with other immune cells
-
all of these
Questão 32
Questão
Fc region is involved in
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cell surface receptor binding
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complement activation
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determining diffusivity of antibody molecule
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all of these
Questão 33
Questão
The ability of antigen to stimulate antibody production is called
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Affinity
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Antigenicity
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Elicitation
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none of these
Questão 34
Questão
Clearance of antigens by antibodies involve
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neutralization and agglutination
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opsonisation and complement activation
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precipitation
-
all of these
Questão 35
Questão
The two identical light chains of an antibody belongs to
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kappa only
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lambda only
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lambda or kappa
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none of these
Questão 36
Questão
Antigens can be
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proteins
-
carbohydrates
-
nucleic acids
-
all of these
Questão 37
Questão
A molecule that reacts with specific antibody but is not immunogenic by itself is called
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carrier
-
antigen
-
hapten
-
immunogen
Questão 38
Questão
Haptens are immunogenic upon binding covalently to a carrier protein how?
Responda
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covalently to a carrier protein
-
covalently to an antibody
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covalently to a paratope
-
none of these
Questão 39
Questão
Haptens cannot activate T cell or B cells due to:
Responda
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its low molecular weight antigens arbuscules
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its inability to bind to MHC
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both a and b
-
none of these
Questão 40
Questão
Which of the following is a hapten?
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Cyanide
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Paracetamol
-
Penicillin
-
None of these
Questão 41
Questão
An incomplete antigens
Responda
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are also called as haptens
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are immunogenic upon binding covalently to a carrier protein
-
cannot induce antibody production by itself
-
all of the above
Questão 42
Questão
The second most abundant Ig is
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IgM
-
IgG
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IgA
-
IgE
Questão 43
Questão
The most effective Ig is:
Responda
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IgM
-
IgG
-
IgA
-
IgE
Questão 44
Questão
IgM is a
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pentamer with 10 antigen binding sites
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tetramer with 8 antigen binding sites
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monomer with 2 antigen binding sites
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dimer with 4 antigen binding sites
Questão 45
Questão
The Ig that mediates allergic reaction is
Responda
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IgM
-
IgG
-
IgA
-
IgE
Questão 46
Questão
The Ig involved in host defence against parasitic infection (helminths)
Responda
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IgM
-
IgG
-
IgA
-
IgE
Questão 47
Questão
The bonds involved in antigen-antibody interactions are
Responda
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weak hydrogen bonds and vanderwalls forces
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strong covalent bonds
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strong di- sulphide bonds
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all of these
Questão 48
Questão
Which of the following statement is true?
Responda
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all immunogens are antigens but all antigens are not immunogens
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all immunogens are antigens and all antigens are immunogens
-
all immunogens are not antigens but all antigens are immunogens
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all immunogens are proteins and all proteins are immunogens
Questão 49
Questão
Which of the statements are true regarding antigen?
Responda
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generally self-molecules and molecules with low molecular weight are non-immunogenic
-
an antigen generally has many epitopes
-
heteropolymers are more immunogenic than homopolymers
-
all of these
Questão 50
Questão
The process of removal and replacement of damaged tissues or organs with healthy ones from a donor is called as
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transplantation
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replacement therapy
-
repair and replacement
-
none of these
Questão 51
Questão
The transfer of individuals own tissue to another part of the body is called
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autograft
-
xenograft
-
allograft
-
syngeneic graft
Questão 52
Questão
The transfer of tissue between genetically identical individuals (like twins) is called
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autograft
-
xenograft
-
allograft
-
syngeneic graft
Questão 53
Questão
The transfer of tissue between individuals of different species is called
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-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Questão 54
Questão
The transfer of tissue between genetically different individuals of same species is called
Responda
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Questão 55
Questão
Which of the following has the maximum transplantation success rate?
Responda
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Questão 56
Questão
The major molecules responsible for rejection of transplant is
Responda
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B cells
-
T cells
-
MHC molecule
-
Antibodies
Questão 57
Questão
Which of the following statements are true regarding transplantation?
Responda
-
The compatibility of MHC proteins of donor and recipient will determine the success of transplantation
-
MHCs are just like fingerprints and all nucleated cells possess this fingerprint
-
The compatibility of MHC/HLA proteins of donor and recipient will be high if they are genetically closely related and may lead to successful transplantation.
-
all of these
Questão 58
Questão
In humans, MHC is called as
Responda
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Human MHC
-
Homo MHC
-
Human leucocyte antigen (HLA)
-
All of the above
Questão 59
Questão
The genes for HLA proteins are clustered in the major histocompatibility complex located
Responda
-
on the short arm of chromosome 6
-
on the long arm of chromosome 6
-
on the short arm of chromosome 10
-
on the long arm of chromosome 10
Questão 60
Questão
The test that is done prior to transplantation surgery to determine the compatibility of MHC proteins between donor and recipient is called
Responda
-
MHC matching
-
MHC typing
-
tissue typing
-
blood HLA test
Questão 61
Questão
MHC class I is a cell surface molecule present on
Responda
-
B cells
-
All nucleated cells
-
APCs
-
T cells
Questão 62
Questão
MHC class II is a cell surface molecule present on
(most correct ans.)
Responda
-
B cells
-
All nucleated cells
-
APCs
-
T cells
Questão 63
Questão
Which of the following statements are true regarding complement activation?
Responda
-
lysis of pathogen, tumor cells and allografts
-
production of mediators that attracts neutrophils to the site of inflammation
-
opsonization
-
all of these
Questão 64
Questão
Complement system is involved in
Responda
-
specific defence
-
non-specific defence
-
both a and b
-
none of these
Questão 65
Questão
Allergy to penicillin is an example of
Responda
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Questão 66
Questão
Type IV hypersensitivity is also called as:
Responda
-
immediate hypersensitivity
-
delayed hypersensitivity
-
cytotoxic hypersensitivity
-
immune complex hypersensitivity
Questão 67
Questão
The most common class of antibody involved in type II hypersensitivity is
Responda
-
IgG
-
IgM
-
IgE
-
IgD
Questão 68
Questão
T helper cell mediated hypersensitivity is:
Responda
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Questão 69
Questão
Type III hypersensitivity is triggered by:
Responda
-
Mast cells and IgE
-
K cells and IgG
-
Deposition of antigen antibody complexes
-
Th cells
Questão 70
Questão
Autoimmune hemolytic anemia (AHA) is an example of
Responda
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Questão 71
Questão
K cells and IgG mediated hypersensitivity is
Responda
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Questão 72
Questão
Antibody dependent cytotoxicity is associated with
Responda
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Questão 73
Questão
Allergies to sea foods, eggs etc is an example of
Responda
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Questão 74
Questão
Humoral immunity is mediated by
Responda
-
B cells
-
macrophages
-
both a and b
-
phagocytes
Questão 75
Questão
Humoral immunity is also called as
Responda
-
antibody mediated immunity
-
non-specific immune response
-
antigen mediated immunity
-
all of these
Questão 76
Questão
B cell has receptor on its surface which is
Responda
-
monomeric IgM
-
dimeric IgM
-
monomeric IgG
-
B cell receptor
Questão 77
Questão
B cells upon activation by antigens
Responda
-
undergo clonal expansion followed by clonal selection
-
divides continuously
-
undergo clonal selection followed by clonal expansion
-
secrete antibodies
Questão 78
Questão
B cells differentiates to form
Responda
-
plasma cells only
-
effector cells only
-
plasma cells and memory B cells
-
none of these
Questão 79
Questão
Which of the following statement is incorrect regarding plasma cells?
Responda
-
Plasma cells are the effector cells
-
Plasma cells secretes antibodies
-
The precursor of plasma cell is B cell
-
Plasma cell has surface receptors
Questão 80
Questão
Origin and maturation of B cells takes place at
Responda
-
lymph nodes
-
bone marrow
-
thymus
-
spleen
Questão 81
Questão
The function of memory B cell is
Responda
-
antibody production
-
immunologic memory
-
regulated antibody production
-
none of these
Questão 82
Questão
Generally antibodies produced against a pathogen is
Responda
-
monoclonal
-
homogenous
-
polyclonal
-
all of same specificity
Questão 83
Questão
Antibodies produced by plasma cells are
Responda
-
specific
-
produced against the epitope that triggered B cell activation
-
both a and b
-
diverse
Questão 84
Questão
Antibodies clear out antigens by
Responda
-
neutralization
-
precipitation
-
agglutination
-
all of these
Questão 85
Questão
Antibodies are
Responda
-
opsonins
-
lipoproteins
-
serum phagocytes
-
none of these
Questão 86
Questão
Any substance that promotes phagocytosis of antigens by binding to them are called as
Responda
-
interleukins
-
macrophages
-
phagocytes
-
opsonins
Questão 87
Questão
The phenomenon of selective proliferation of B cells in response to their interaction with the antigen is called
Responda
-
clonal expansion
-
monoclonal selection
-
clonal proliferation
-
clonal selection
Questão 88
Questão
The specific targeted responses constitute the third line of defense in response to an infectious agent and is called as
Responda
-
third line of defence
-
adaptive immunity
-
acquired immunity
-
all of these
Questão 89
Questão
The characteristics of adaptive immunity include
Responda
-
specificity
-
immunologic memory
-
discrimination of self from non self molecules
-
all of these
Questão 90
Questão
Which of the cells are involved in adaptive immunity?
Responda
-
B cells and T cells
-
B cells only
-
T cells only
-
macrophages and NK cells
Questão 91
Questão
T cell mediates
Responda
-
humoral immunity
-
non-specific defence
-
cell mediated immunity
-
none of these
Questão 92
Questão
The ratio of T cells to B cells is
Responda
-
3:1
-
1:3
-
1:1
-
1:2
Questão 93
Questão
T cells and B cells are originated in
Responda
-
spleen
-
thymus
-
bone marrow
-
lymph nodes
Questão 94
Questão
Injection of anti-venom against snake bite is an example of
Responda
-
active immunity
-
passive immunity
-
non-specific immunity
-
phagocytic immunity
Questão 95
Questão
Which of the following statements are true regarding adaptive immunity?
Responda
-
prior exposure to antigen is essential
-
prior exposure to antigen is not essential
-
it is a non-specific defence mechanism
-
macrophages are the major cells involved
Questão 96
Questão
Active immunity involves
Responda
-
contact with foreign antigens
-
immunologic memory
-
slow primary response
-
all of the above
Questão 97
Questão
Active immunity is produced by
Responda
-
clonal selection
-
clonal expansion
-
both a and b
-
all of these
Questão 98
Questão
Cells involved in adaptive immunity or acquired immunity or specific defense include
Responda
-
T cells
-
B cells
-
Antigen presenting cells
-
All of these
Questão 99
Questão
Plasma cells are secreted by
Responda
-
T cells
-
B cells
-
Antigen presenting cells
-
Macrophages
Questão 100
Questão
The characteristics of passive immunity include
Responda
-
immediate relief
-
no immunologic memory
-
resistance for a short period only
-
all of these
Questão 101
Questão
Immunologic memory is provided by
Responda
-
B cells
-
T cells
-
Both a and b
-
Phagocytes
Questão 102
Questão
A method for cell sorting based on the surface antigens (markers) which react specifically with fluorescent-labelled antibodies is called
Responda
-
Flowcytometry
-
Immunofluorescent technique
-
Immunoelectrophoresis
Questão 103
Questão
A technique in which tissues and cells are examined by a fluorescent light microscope using fluorescent-labeled antibodies is called
Responda
-
Immunofluorescent technique
-
Flowcytometry
-
Immunoelectrophoresis
Questão 104
Questão
A technique for the identification of proteins in serum or other fluid by electrophoresis and subsequent immunodiffusion is called
Responda
-
Immunoelectrophoresis
-
Flowcytometry
-
Immunofluorescent technique
Questão 105
Questão
Classical pathway of complement system is activated by
Responda
-
antibody-antigen complexes
-
antigen
-
antigenic peptides
-
antigens bound to MH
Questão 106
Questão
Alternate pathway of complement system is activated by
Responda
-
antibody-antigen complexes
-
antigen
-
microorganisms or its toxins
-
antigens bound to MHC
Questão 107
Questão
Classical pathway of complement system is involved in
Responda
-
specific defence
-
adaptive immunity
-
both a and b
-
non-specific defence
Questão 108
Questão
Alternate pathway of complement system is involved in
Responda
-
non-specific defence
-
innate immunity
-
both a and b
-
adaptive immunity
Questão 109
Questão
Complement system
Responda
-
consists of 20 serum proteins
-
serum proteins acts as biological cascade
-
both a and b
-
are set of antibodies
Questão 110
Questão
Complement system is involved in
Responda
-
specific defence
-
non-specific defence
-
both a and b
-
none of these
Questão 111
Questão
Kupffer cells are macrophages found on
Responda
-
lung
-
bone
-
nephrons
-
liver
Questão 112
Questão
Antiviral glycoproteins released by living cells in response to viral attack and induce a viral resistant state to neighboring cells is called as
Responda
-
natural killer cells
-
complement system
-
phagocytes
-
interferons
Questão 113
Questão
Newborns get their antibodies from mothers milk. This is an example of
Responda
-
Naturally acquired active immunity
-
Artificially acquired active immunity
-
Naturally acquired passive immunity
-
Artificially acquired passive immunity
Questão 114
Questão
Which of the following is the site of T cell maturation?
Responda
-
Bone marrow
-
Thymus
-
Spleen
-
Appendix
Questão 115
Questão
Primary lymphoid organs include
Responda
-
Thymus and spleen
-
Thymus and bone marrow
-
Thymus, bone marrow and spleen
-
Thymus, bone marrow, spleen and lymph nodes
Questão 116
Questão
The major chemical messenger involved in hypersensitivity is
Responda
-
interferons
-
histamines
-
lymphokines
-
interleukines
Questão 117
Questão
HIV attacks:
Responda
-
macrophages
-
B cells
-
T cytotoxic cells
-
T helper cells
Questão 118
Questão
Regarding the inflammatory response:
Responda
-
Tissue swelling is the first stage of the inflammatory response.
-
Mast cells secrete chemotactic agents that attract lymphocytes
-
Macrophages secrete vasoactive materials during the inflammatory response
-
The inflammatory response can be triggered by antibody binding to the surface of micro-organisms.
Questão 119
Questão
Natural killer cells only destroy cells infected with a virus.
Responda
- True
- False
Questão 120
Questão
The antigens below are on your erythrocytes (red blood cells) which antibodies would you expect to find in the serum
1/ A- [blank_start]B[blank_end]
2/ B- [blank_start]A[blank_end]
3/ O- [blank_start]AB[blank_end]
Responda
-
B
-
A
-
AB
-
O
-
A
-
B
-
AB
-
O
-
AB
-
O
-
A
-
B
Questão 121
Questão
Fill in the Blanks (No - symbol needed)
1/ Precursor Chain + [blank_start]L fucose[blank_end]= H-Antigen
2/ H-Antigen + [blank_start]N acetylgalactosamine[blank_end]= A-Antigen
3/ H-Antigen + [blank_start]D Galactose[blank_end]= B-Antigen
Responda
-
L fucose
-
N acetylgalactosamine
-
D Galactose
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