630602
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
mais de 10 anos atrás
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Questão 1
Questão
B Cells recognise native antigens, T cells recognise processed antigens
Responda
- True
- False
Questão 2
Questão
Which of the following are NOT professional antigen presenting cells?
Responda
-
Neutrophils
-
Macrophages
-
Dendritic cells
Questão 3
Questão
CD8 T-cells recognise which MHC complex?
Responda
-
MHCI
-
MHCII
Questão 4
Questão
CD4 is for the detection of virally infected cells
Responda
- True
- False
Questão 5
Questão
CD4 cells recognise MHCII, which uses which Antigen processing system?
Responda
-
Endosomal
-
Endogenous
-
Endomal
Questão 6
Questão
Cells with MHCI present using the endogenous AP system
Responda
- True
- False
Questão 7
Questão
T- cells cannot recognise soluble, native antigens
Responda
- True
- False
Questão 8
Questão
Put the following steps in the correct order- A (Antigen-MHC Complex Formation), B (Uptake), C (Presentation) and D (Degredation
Responda
-
B-D-A-C
-
A-B-D-C
-
A-C-B-D
Questão 9
Questão
Which of the following definitions is incorrect?
Responda
-
Uptake- picking up of the antigen from surrounding fluid
-
Degredation- total digestion of the antigen
-
Presentation- movement of the complex to the cell surface
Questão 10
Questão
Endosomal Pathway- What is it for?
Responda
-
Processing of extracellular antigens picked up by antigen presenting cells
-
Processing of cytosolic viral antigens
Questão 11
Questão
Endosomal Pathway- Uses the MHCI complex
Responda
- True
- False
Questão 12
Questão
Endosomal Pathway- The extracellular antigen is picked up by phagocytosis
Responda
- True
- False
Questão 13
Questão
Endosomal Pathway- How is picking up of the antigen mediated?
Responda
-
Receptor mediated
-
Compliment mediated
-
Hormone mediated
Questão 14
Questão
Endosomal Pathway- The antigen containing endosome only binds to the MCHII containing endosome after partial digestion
Responda
- True
- False
Questão 15
Questão
Endosomal Pathway- How is the active site of MHCII covered in the cell?
Responda
-
Covered by an invariant 'cap'
-
The two parts are connect by a subunit that must be removed
-
Receptor surface is bound to the endosome envelope
Questão 16
Questão
Endosomal Pathway- The cover of the MHC complex is called a CLIP
Responda
- True
- False
Questão 17
Questão
Endosomal Pathway- How is the processed antigen added to the MHCII complex?
Responda
-
Acessory proteins swap the CLIP for the peptide when the two vesicles fuse
-
Acessory proteins remove the MHCII from the envelope when the two vesicles fuse
-
Acessory proteins remove the subunit connecting the two halves when the two vesicles fuse
Questão 18
Questão
Endogenous Pathway- Main use is for what?
Responda
-
Viral antigen processing
-
Professional pesentation of antigens
Questão 19
Questão
Endogenous Pathway uses MHCII
Responda
- True
- False
Questão 20
Questão
Endogenous Pathway- How are cytosolic antigens processed?
Responda
-
By the TCR
-
By MHCI
-
By cytosolic proteases
Questão 21
Questão
Endogenous Pathway- Digested peptides are moved into the Golgi by what?
Responda
-
Transporter Associated with Antigen Processing (TAP 1&2)
-
Transporter Associated with Antigen Digestion (TAD 1&2)
-
Transporter Associated with Antigen Presentation (TAP 1&2)
Questão 22
Questão
In the Golgi the processed peptide is bound to MHCI and they complex is loaded into a vesicle for transport to the cell membrane
Responda
- True
- False
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