Biochemistry MCQs 3rd Coloquim PMU 2nd Year

Question

Which are the regulatory enzymes in glycolysis?

Answer 1

Hexokinase

Answer 2

Glucose-6-phosphate Isomerase

Answer 3

Phosphofructokinase

Answer 4

Phosphoglycerate Mutase

Answer 5

Pyruvate Kinase

Answer 6

Glucose-6-phosphate Dehydrogenase

Answer 7

Transaldolase

Answer 8

Transketolase

Answer 9

Phosphofructokinase

Answer 10

Pyruvate Kinase

Answer 11

Endoplasmic Reticulum

Answer 12

Mitochondria

Answer 13

Both Cytosol and Endoplasmic Reticulum

Answer 14

Cytosol, Mitochondria and Endoplasmic Reticulum

Answer 15

Isocitrate

Answer 16

Oxaloacetate

Answer 17

Succinyl-CoA

Answer 18

Vitamin H (biotin)

Answer 19

Vitamin B1 (thiamine pyrophosphate)

Answer 20

Vitamin PP (NAD, NADH)

Answer 21

Vitamin B2 (FAD, FMN)

Answer 22

GTP and UTP

Answer 23

ATP and GTP

Answer 24

ATP and UTP

Answer 25

Acetyl-CoA

Answer 26

Glucose-6-Phosphate

Answer 27

succinyl-CoA

Answer 28

α-ketoglutarate

Answer 29

oxaloacetate

Answer 30

the enzyme activity of fructose 1,6-bisphosphatase is increased by ΑΤΡ

Answer 31

the enzyme activity of fructose 1,6-bisphosphatase is increased by ADP

Answer 32

the enzyme activity of fructose l,6-bisphosphatase is decreased by ATP

Answer 33

the enzyme activity of fructose 1,6-bisphosphatase is decreased by ADP

Answer 34

fructose 2,6-bisphosphate is the most potent activator for gluconeogenesis and Inhibitor for glycolysis

Answer 35

Pyruvate carboxylase

Answer 36

Glucose-6-phosphatase

Answer 37

Phosphofructokinase

Answer 38

Pyruvate kinase

Answer 39

ΡΕΡ carboxykinase

Answer 40

adrenaline

Answer 41

Is stimulated by insulin

Answer 42

Is stimulated by glucagon

Answer 43

Is major pathway in liver and kidneys

Answer 44

Can also be performed in muscles

Answer 45

Causes a decrease in blood glucose level

Answer 46

Hexokinase is not a regulatory enzyme

Answer 47

Glucokinase is not inhibited allosterically by glucose-6-phosphate

Answer 48

Phosphofructokinase 1 is the most important regulatory enzyme

Answer 49

Fructose-2,6-bisphosphate activates glycolysis

Answer 50

Insulin causes a decrease in the concentration of fructose-2,6-bisphosphate

Answer 51

Insulin is secreted in periods of starvation

Answer 52

Insulin is secreted by α-cells of the pancreas to decrease blood glucose level after meal

Answer 53

Glucagon is secreted in case of low blood glucose levels

Answer 54

Insulin stimulates pentose phosphate pathway

Answer 55

Glucagon is the main hormone that stimulates gluconeogenesis

Answer 56

Is a linear polymer composed only of glucose residues

Answer 57

Is synthesized in response to insulin stimulation over the main regulatory enzyme- the branching enzyme

Answer 58

Is present at any cell but most prominently in liver and muscle cells

Answer 59

Is synthesized in periods of starvation

Answer 60

Its regulatory enzymes both in synthesis and degradation can be controlled allosterically as well as through reversible covalent modification

Answer 61

the main regulative enzyme in glycolysis is phosphofructokinase 1

Answer 62

the main regulative enzyme in glycolysis is glyceraldehyde-1-phosphate dehydrogenase

Answer 63

hexokinase involved in glycolysis is regulated by product of the reaction- glucose-6-phosphate

Answer 64

pyruvate kinase involved in glycolysis is regulated by covalent modification (reversible phosphorylation/ dephosphorylation) only in the liver

Answer 65

pyruvate kinase involved in glycolysis is regulated by covalent modification (reversible phosphorylation/ dephosphorylation) only in the tissues

Answer 66

propionate

Answer 67

acetyl-COA

Answer 68

Erythrose-4-phosphate

Answer 69

Fructose-1,6-bisphosphate

Answer 70

Glucose-6-phosphate

Answer 71

Glyceraldehyde-3-phosphate

Answer 72

Dihydroxyacetone phosphate

Answer 73

Fructose-6-phosphate

Answer 74

The regulatory enzyme is glycogen phophorylase

Answer 75

The regulatory enzyme is debranching enzyme

Answer 76

The regulatory enzyme is activated by ATP and glucose-6-phosphate

Answer 77

It is a source of energy for the liver itself

Answer 78

It is most fast activated mechanism for maintenance of blood glucose level in periods of fasting

Answer 79

The degradation stops till glucose-6-phosphate

Answer 80

It is absorbed mainly through GLUT5

Answer 81

Can be metabolized in muscles by fructokinase and enter glycolysis in one step

Answer 82

Can be metabolized in liver, skeletal muscles, spermatozoa and other extrahepatic tissues but by different enzymes

Answer 83

A deficiency in aldolase B causes fructose intolerance

Answer 84

In liver fructose enters glycolysis at the level of trioses-glyceraldehyde-3-phosphate and dihydroxyacetone phosphate

Answer 85

Glycolysis

Answer 86

Gluconeogenesis

Answer 87

Synthesis of glycogen

Answer 88

Degradation of glycogen

Answer 89

Galactose metabolism

Answer 90

Pentose phosphate pathway

Answer 91

at high insulin levels

Answer 92

at low insulin levels

Answer 93

at high blood glucose content

Answer 94

at low blood glucose content

Answer 95

in fasting

Answer 96

liver glycogen stores and exports glucose to maintain blood glucose

Answer 97

liver and muscles lack glucose-6-phospatase

Answer 98

the synthesis of glycogen is initiated by the formation of glycogen primer

Answer 99

the cleavage of glycogen by glycogen phosphorylase yields UDPGlc

Answer 100

glycogen phosphorylase is active phosphorylated

Answer 101

hormones like glucagon and adrenaline increase glycogenolysis

Answer 102

a rise in cAMP concentration activates glycogen synthase

Answer 103

insulin increases glycogenolysis

Answer 104

glucogenic amino acids

Answer 105

acetyl-CoA

Answer 106

it generates NADPH for reductive biosynthesis

Answer 107

it generates ribose phosphate for nucleotide and nucleic acids formation

Answer 108

the enzymes of PPP are mitochondrial

Answer 109

PPP protects the erythrocytes against hemolysis

Answer 110

citrate and ATP are allosteric inhibitors of phosphofructokinase-1

Answer 111

fructose-2,6-bisphosphate is an allosteric activator of phosphofructokinase-1

Answer 112

phosphofructokinase-1 activity is increased by insulin

Answer 113

phosphofructokinase-1 activity is increased by glucagon

Answer 114

Hexokinase

Answer 115

Glucose-6-phosphatase

Answer 116

Phosphofructokinase

Answer 117

Pyruvate kinase

Answer 118

PEP carboxykinase

Answer 119

glycolysis

Answer 120

gluconeogenesis

Answer 121

glycogen degradation

Answer 122

glycogen synthesis

Answer 123

It is the major donor of NADH+H+

Answer 124

It is the major donor of NADPH+H+

Answer 125

It is located in the mitochondria

Answer 126

Its major goal is generation of energy

Answer 127

it produces reducing agents for various synthesis but also ribose for nucleic acids formation

Answer 128

Glucokinase

Answer 129

Phosphoglucomutase

Answer 130

Phosphoenolpvruvate carboxykinase

Answer 131

Pyruvate kinase

Answer 132

Pyruvate carboxylase

Answer 133

Glucose-6-phosphatase

Answer 134

Fructose-1,6-bisphosphatase

Answer 135

ls metabolized both in liver and extrahepatic tissues

Answer 136

Is metabolized only in liver

Answer 137

Its metabolism requires UDP

Answer 138

Can be used for maintenance of blood glucose level

Answer 139

Galactosemia type I (classical) is caused by deficiency in galactokinase

Answer 140

Glycolysis can be performed either in aerobic or anaerobic conditions

Answer 141

The terminal product of glycolysis is always lactate

Answer 142

RBC contain smaller amounts of 2,3 bisphosphoglycerate compared the rest of the cells

Answer 143

Pentose phosphate pathway is of vital importance for the RBC

Answer 144

RBC participate in Cori Cycle

Answer 145

all of the enzymes of glycolysis are in the cytosol

Answer 146

glucokinase is an isoenzyme of hexokinase in liver and pancreatic β-cells

Answer 147

phosphofructokinase-1 is a major regulatory enzyme of glycolysis

Answer 148

glycolyis is a pathway that can function only aerobically

Answer 149

ls a branched polymer composed only of glucose residues

Answer 150

The main regulatory enzyme of its synthesis - glycogen synthase, is activated by epinephrine

Answer 151

ls present most prominently in liver and muscle cells but has different function in them

Answer 152

The regulatory enzymes both in synthesis and degradation can be controlled allosterically as well as through reversible covalent modification

Answer 153

α-(1->6) glycosidic bond cleavage is executed by glycogen phosphorylase

Answer 154

Insulin is secreted in response to hyperglycemia

Answer 155

Insulin is secreted in response to hypoglycemia

Answer 156

Glucagon is activator of gluconeogenesis and glycogen degradation

Answer 157

Insulin inhibits pentose phosphate pathway

Answer 158

Insulin activates phosphofructokinase 1 and thus glycolysis

Answer 159

Fructose-2,6-bisphosphate is aIIosteric activator of glycoiysis and inhibitor of giuconeogenesis

Answer 160

Fructose-2,6-bisphosphate is allosteric inhibitor of glycoiysis and activator of giuconeogenesis

Answer 161

ATP and citrate are inhibitors of glycolysis

Answer 162

AMP is an activator of glycoiysis

Answer 163

Deficiency in glucose-6-phosphate dehydrogenase may cause haemolytic anaemia

Answer 164

Fructose is metabolized only in liver

Answer 165

Fructosuria is caused by deficiency in fructokinase

Answer 166

Glucose is transported in liver and pancreas through GLUT 3

Answer 167

Hexokinase is not a regulatory enzyme

Answer 168

Glucokinase is not inhibited allosterically by glucose-6-phosphate

Answer 169

Phosphofructokinase 1 is the most important regulatory enzyme

Answer 170

Fructose-2,6-bisphosphate activates glycolysis

Answer 171

Insulin causes a decrease in the concentration of fructose-2,6-bisphosphate

Answer 172

glycogen phosphorylase is active dephosphorylated

Answer 173

hormones like glucagon and adrenaline increase glycogen synthesis

Answer 174

a rise in cAMP concentration activates glycogen phosphorylase

Answer 175

insulin increases glycogen synthesis

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Biochemistry MCQs 3rd Coloquim PMU 2nd Year

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