967975
Descrição
Quiz por emmabrudenell, atualizado more than 1 year ago
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Criado por emmabrudenell
mais de 10 anos atrás
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Questão 1
Questão
Homozygous mutations of PAX6 in humans cause Aniridia
Responda
- True
- False
Questão 2
Questão
what is at the vegetal pole of xenopus oocytes
Responda
-
Veg-1
-
yolk
-
Most mRNA's
-
ribosomes
-
tRNA's
Questão 3
Questão
What is the cortical reaction?
Responda
-
a block to polyspermy in the sea urchin
-
The sperm penetrating through the egg membrane
-
Activation of the egg once sperm has enters
Questão 4
Questão
What is the correct order of the life cycle of embryo development to adult
Responda
-
zygote->cleavage->gastrulation-> neurulation ->organogenesis->metamorphosis->adult
-
zygote->cleavage->gastrulation-> organogenesis->neurulation->metamorphosis->adult
-
zygote->cleavage->gastrulation-> neurulation ->metamorphosis->organogenesis->adult
-
zygote->cleavage-> neurulation->gastrulation ->organogenesis->metamorphosis->adult
Questão 5
Questão
Which of the following apply the the PAX6 gene in drosophila
Responda
-
Paired gene
-
chromosome 11
-
Gap gene
-
chromosome 2
Questão 6
Questão
Genes can change activity during development
Responda
- True
- False
Questão 7
Questão
which of the following are cleavage patterns
Responda
-
Holoblastic
-
Meroblastic
-
Superlateral
-
All of these
Questão 8
Questão
Sperm entry to the egg triggers Mg2+ release which acts on cell cycle proteins and initiates cleavage
Responda
- True
- False
Questão 9
Questão
What does mesoderm give rise to?
Responda
-
Cartilage
-
Muscle
-
Bone
-
Dermis
-
Kidney
-
Blood
-
Gut tissue
-
epidermis
-
Nervous system
Questão 10
Questão
What does ectoderm turn into
Responda
-
Epidermis
-
Nervous system
-
Gut tissue
-
Bone
-
Cartilage
-
Muscle
Questão 11
Questão
C.elegans has no hedgehog signalling
Responda
- True
- False
Questão 12
Questão
Which of these apply to the mutagenesis technique?
Responda
-
Random gene is altered
-
specific gene is altered
-
Males treated with mutagen and crossed with wild-type females
-
Females treated with mutagen and crossed with wild-type males
-
recombinant DNA technology
Questão 13
Questão
Which of these apply to the transgenesis technique?
Responda
-
Random gene is altered
-
specific gene is altered
-
gain of function of gene
-
loss of function of gene
-
recombinant DNA technology
Questão 14
Questão
Which of these apply to the mutagenesis technique?
Responda
-
Random gene is altered
-
specific gene is altered
-
Males treated with mutagen and crossed with wild-type females
-
Females treated with mutagen and crossed with wild-type males
Questão 15
Questão
Which organisms is mutagenesis a suitable gene
Responda
-
Fly and zebrafish
-
worm, Fly and zebrafish
-
zebrafish
-
mouse, worm, Fly and zebrafish
Questão 16
Questão
commitment is not shown by a fate map
Responda
- True
- False
Questão 17
Questão
Regulative development is shown by models from the following scientists
Responda
-
Driesh- sea urchin
-
Roux- frog
-
Both of these
Questão 18
Questão
Which of the following applies to regulative development?
Responda
-
damage to cells early on in development does not result in a defective organism
-
damage to cells early on in development results in a defective organism
-
Cells determined early on
-
non-autonomous development
Questão 19
Questão
most type of development is mosaic
Responda
- True
- False
Questão 20
Questão
which of the following apply to the bicoid mRNA
Responda
-
highest concentration at posterior end
-
Maternal affect gene
-
transcription factor
-
mutant larva lack thoracic segments
Questão 21
Questão
The french flag model is a model for mosaic development
Responda
- True
- False
Questão 22
Questão
Which experiment(s) is used to demonstrate competence?
Responda
-
xenopus cap assay
-
Amphibian organiser
-
Both of these
Questão 23
Questão
How many somites die in the C.elegans embryo
Responda
-
none
-
5
-
72
-
131
-
896
Questão 24
Questão
Which of the following are properties of an ideal marker?
Responda
-
non toxic
-
leaks so all cells have the marker
-
Inherited by all progeny of the labelled cells
-
visible at later stages
Questão 25
Questão
Which of the following are properties of an ideal marker?
Responda
-
non toxic
-
leaks so all cells have the marker
-
Inherited by all progeny of the labelled cells
-
visible at later stages
Questão 26
Questão
Which of the following are examples of markers
Responda
-
cytological markers
-
vital dyes
-
high molecular weight tracers
-
all of these
Questão 27
Questão
MyoD is sufficient and required for muscle development
Responda
- True
- False
Questão 28
Questão
Which term is this definition for? - over expression of transcription unit, it is a gain of function mutation
Responda
-
amorph
-
hypomorph
-
hypermorph
-
Antimorph
Questão 29
Questão
In the Brachyury gene in the mouse, a homozygous mutation results in?
Responda
-
short tail
-
embryonic lethal
Questão 30
Questão
which organism(s) are unsuitable for mutagenesis and a mutagenesis screen
Responda
-
frog and chick
-
chick
-
frog, chick and bacteria
-
frog, chick and mouse
Questão 31
Questão
Different mutations in the same gene is called and allelic series
Responda
- True
- False
Questão 32
Questão
In complementation testing, if two genes complement each other they ...
Responda
-
are alleles of the same gene, so lie in the same chromosome
-
do not lie in the same chromosome
Questão 33
Questão
what are epistasis experiments used for?
Responda
-
working out the order of gene action in a pathway
-
working out which genes are in a pathway
-
working out if mutations are on the same or different genes
-
working out the genotype of a mutant
Questão 34
Questão
The drosophila gene 'white' is required for the development of white eyes
Responda
- True
- False
Questão 35
Questão
which of the following are defects from kit and steel mutations?
Responda
-
Anaemia
-
coat pigmentation
-
embryonic lethal
-
short tail
Questão 36
Questão
There are two classes of segment polarity genes; hedgehog-like and patched-like. Which genes belong to the hedge-hog like?
Responda
-
Hh
-
Smo
-
Wg
-
all of these
Questão 37
Questão
The body plan along the embryo is controlled by Hox genes along the DV axis
Responda
- True
- False
Questão 38
Questão
which of the following maternal effect gene(s) are in the ventralised class?
Responda
-
Dorsal
-
Spatzle
-
Toll
-
cactus
Questão 39
Questão
what does local application of FGF4 after removal of AER results in..
Responda
-
no effect
-
limb development- radius and ulna fully developed but only partial digit development
-
limb development- but only partial development
-
limb development- Digits fully developed but radius and ulna only partially developed
Questão 40
Questão
Length of time spent in AER determines cell fate according to position over proximal distal axis.
Responda
- True
- False
Questão 41
Questão
In proneural clusters, one cells becomes a neuroblast (primary fate), whilst the other cells become the secondary fate which is..
Responda
-
epidemermis
-
neurons
-
fibroblasts
-
mesenchyme
Questão 42
Questão
The proneural cluster gives rise to a neuroblast through lateral inhibition of which receptor and ligand pair?
Responda
-
Kit and steel
-
Delta and Notch
-
FGF and FGFR
-
Delta and steel
Questão 43
Questão
Most forms of Anchondroplasia come from mutations in which FGF gene?
Responda
-
FGF2
-
FGF3
-
FGF4
-
FGF5
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