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Microbiology MCQs 3rd Year Final- PMU

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Microbiology MCQs 3rd Year Final- PMU
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Created by Med Student almost 7 years ago
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Question 1

Question
The reaction of antibody with a non soluble antigen or an antigen-cated particles result in formation of visible to the eye clumb is called
Answer
  • agglutination
  • precipitation
  • neutralization
  • complement fixation test

Question 2

Question
ELlSA makes use of:
Answer
  • fluorenlubels
  • enzyme
  • radioactive lubels
  • It is not a labeled immune for...

Question 3

Question
widal from used to.....
Answer
  • slide agglutination test
  • tube agglutination
  • CUT
  • lectin pathway

Question 4

Question
Which of the following immunoglobulins may be transferes to the fetus during pregnancy
Answer
  • lgG
  • lgM

Question 5

Question
The genus specific name for group A streptococci is
Answer
  • streptococcus pneumonia
  • streptococcus viridans
  • streptococcus diphtheria
  • streptococcus pyogenes

Question 6

Question
The main pathogenic factor of corynebacterium diphtheria is
Answer
  • an endotoxin
  • an exotoxin
  • a spore
  • a protein

Question 7

Question
The specific prophylaxis of diphtheria is performed by
Answer
  • a toxoid
  • a killed vaccine
  • passive transfer at serum
  • a live vaccine

Question 8

Question
Which of the following statement concerning cholera infection is correct?
Answer
  • death occurs in 46 weeks exclusion and respiratory failure
  • the disease is marked by microorganism invasion and hemorrhage of large intestine
  • vibrio cholera produce an acute fehrile disease with
  • the disease is rapidly progressive and maybe fatal in 2 days because of bacterial multiplication in the gut and shock

Question 9

Question
Beta lactamase production is a major problem for treatment of infections caused by:
Answer
  • Corynebacterium diphtheria
  • Neisseria meningitides
  • Staphylococcus aureus
  • Treponemapallidum

Question 10

Question
HIV has been shown to be transmitted by one of the following except
Answer
  • Sexual contact
  • Perinatal infection
  • Mosquitos
  • Blood transfer

Question 11

Question
Each organism is identified by two names including:
Answer
  • family and kingdom
  • genus and species
  • family and species
  • family and genus

Question 12

Question
[blank_start]Simple[blank_end] techniques of staining make use of only one dye,where as [blank_start]Complex[blank_end] staining a combination of dyes?
Answer
  • Simple
  • Complex

Question 13

Question
The volutine granules of corynebacterium diptheria are visualized by [blank_start]Neisser[blank_end] Staining
Answer
  • Neisser

Question 14

Question
The following structure are located in the cytoplasmic membrane?
Answer
  • spore
  • nucleotid
  • ribosomes
  • capsule

Question 15

Question
Based on their cell wall structure bacteria are divided into:
Answer
  • gram(+) and gram(-)
  • aerobe and anerobe
  • sphere and spinal
  • cocci and rods

Question 16

Question
Peptidoglycan polymers are found only in:
Answer
  • bacterial cell
  • animal cell
  • a,b
  • viruses

Question 17

Question
Flagella are present in every bacterium
Answer
  • True
  • False

Question 18

Question
Sporulation appears to be
Answer
  • an initiation of the bacterium cell
  • a reaction to conditions that are unfavorable for normal growth
  • a status to resist desiccation and other harmful conditions
  • a,b
  • b,c

Question 19

Question
The complete killing or removal of all microorganisms including bacterial spores is called?
Answer
  • sterilization
  • disinfection
  • antisepsis
  • non is true

Question 20

Question
Cytoplasm contains:
Answer
  • storage granules
  • spores
  • capsules

Question 21

Question
Which of following component are not found in the gram negative cell wall?
Answer
  • amino acids
  • lipopolysaccharides
  • peptidoglycan
  • teichoic acids

Question 22

Question
Pfeiffer technique of staining makes use of following dye?
Answer
  • methylene blue
  • ziehl’s fuchsine
  • neutral red
  • gentian violet

Question 23

Question
Which of the following structure contains genes for enzymes and antibiotic resistance
Answer
  • plasmld
  • pilli
  • capsules
  • plasma membrane

Question 24

Question
Which of the following is the most important structure related to microbial attachment to cells
Answer
  • flagella
  • plasmid
  • peptidoglycan
  • glycocalix

Question 25

Question
Which of the following is not a gram negative microbe
Answer
  • Clostridum perfringes
  • Vibrio cholerae
  • excheriehia
  • bordetella

Question 26

Question
What causes it to be pink
Answer
  • pheiffer's fuchsine
  • gram iodine
  • crystale violet
  • neisser

Question 27

Question
Selective media are designed to
Answer
  • support the growth of the desires microorganisms
  • inhibit the growth of non-desired microorganisms
  • a+b
  • none of the above

Question 28

Question
Which part of the antibody molecule reacts with the antigenic determinant agent
Answer
  • the fab fragment
  • the fe fragment
  • the constant H region
  • the constants

Question 29

Question
The chemical complement pathway is activated by
Answer
  • microbial endotoxins
  • antigen-antibody complex
  • microbial proteins

Question 30

Question
All of the following statement about exotoxins are true expect
Answer
  • they are produce mainly by gram (+) bacteria
  • they may be neutralized by antitoxins
  • they are proteins
  • they are heat stable at 100*

Question 31

Question
In Solid media bacterial growth is detected by observing
Answer
  • appearance of colonies
  • development of pellet
  • development of turbidity
  • a surface membrane

Question 32

Question
The last phase of bacterial growth curve is:
Answer
  • log phase
  • lag phase
  • stationary phase
  • phase of decline

Question 33

Question
Which of the following component is not found in the gram(-) cell wall
Answer
  • lipopolysaccharide
  • peptidoglycan
  • teichoic acids
  • O antigen

Question 34

Question
The antiseptic is:
Answer
  • an antimicrobial agent that can be used on inanimate object
  • an antimicrobial agent that can be used on living tissue
  • an antibiotic
  • an enzyme

Question 35

Question
Klett is a staining procedure for visualizing:
Answer
  • spores
  • capsules
  • volutine granules
  • nucleotid

Question 36

Question
All of the following media are differential except:
Answer
  • Teilurite agar
  • Eosin-methylene blue agar(Levine)
  • Moller-hiton agar
  • Deoxycholate citrate

Question 37

Question
Immunoprophylaxis of tuberculosis includes:
Answer
  • live affenuated vaccine BCG
  • injection of antimycobacterial serum
  • passive transfer of ready made antibodies from sensitized person
  • a toxoid

Question 38

Question
Passive immunization is an application of:
Answer
  • small doses of infective agent
  • ready made antibodies, formed by another host in response to artificial immunization or to natural infection
  • toxoids
  • killed vaccines

Question 39

Question
Which of the following statements about exotoxins are true:
Answer
  • they are produced mainly by gram(+) bacteria
  • they may be neutralized by antitoxins
  • they are proteins
  • they are heat stable at 100*

Question 40

Question
Which of the following is not a distinctive characteristic of viruses
Answer
  • viruses lack the machinery for protein synthesis
  • viruses require living cells for replication
  • viruses replicate by a process of binary fission
  • viral genomes are either DNA or RNA but not both

Question 41

Question
the immune response elicited by Salk’s inactivated polio vaccine is deficient in specific
Answer
  • secretory lgA
  • serum IgA
  • serum lgM
  • IgG

Question 42

Question
All of the following are characteristics of the human immunodeficiency virus(HIV)expect?
Answer
  • it bind to CD4 molecule preferentially
  • it contains gp120 and gp30 envelope proteins
  • it is the causative agent of AIDS
  • it contains DNA within its core

Question 43

Question
Complement fixation test requires
Answer
  • dissolved antigen
  • corpusculum antigen
  • antitoxin
  • complement

Question 44

Question
Which of the immunoglobin molecule is pentamenie
Answer
  • lgM
  • IgG
  • lgD
  • lgE
  • lgA

Question 45

Question
Resection of the transplanted organ due to preformed antibodies in recipient is defined
Answer
  • hyper acute
  • aclerated
  • acute
  • chronic

Question 46

Question
microorganisms can be defined as living creatures so small that are not visible by eye
Answer
  • True
  • False

Question 47

Question
Loffler staining procedure stains bacteria in
Answer
  • blue
  • red
  • green
  • yellow

Question 48

Question
Which of the following is not true related to endotoxins
Answer
  • are secreted from cells
  • can be linked to meningococcemia
  • produced by gram negative microorganism
  • can cause fever

Question 49

Question
Gram negative bacteria differ from gram(+) organism because they passes?
Answer
  • LPC(A)
  • Peptidoglycan
  • Only a cytoplasmic membrane
  • Lipoteichoic acid

Question 50

Question
Most bacteria increase in number through the process of
Answer
  • binary fission
  • budding
  • sporulation
  • sexual reproduction

Question 51

Question
The term “growth” when for microorganism refer to
Answer
  • increase in cell number
  • production of endospores
  • the age and size of the cell
  • all of the above

Question 52

Question
All of the following statement about bacteria cell division are true except:
Answer
  • all bacteria double their number every 1 hour
  • bacterial times are influenced by environmental conditions
  • the two bacterial cells following division are genetically identical, they are ones
  • all the above

Question 53

Question
Bacterial nucleotid consist of
Answer
  • no chromosomes
  • one chromosome
  • several chromosome

Question 54

Question
Bacterial capsule can be visual sated by:
Answer
  • gram stain
  • loeffler stain
  • klett stain
  • moller stain

Question 55

Question
Lipopolysacharides can be found in large amount in:
Answer
  • gram(+) bacterial wall
  • gram (-) bacterial wall
  • both
  • none of above

Question 56

Question
Complex methods for bacterial staining are
Answer
  • Loeffler stain
  • Pfefiffer stain
  • Gram stain
  • ZiehI-Neelsen stain

Question 57

Question
Specific identity (serotype) of influenza virus can be accomplished by:
Answer
  • hemmagglutination inhibition test
  • neutralization test
  • complement fixation test
  • hemadsorbtion test

Question 58

Question
enlargement of one or both parotid glands in the common clinical manifestation of:
Answer
  • measles
  • mumps
  • rubella
  • grippe

Question 59

Question
The initial replication of human poliovirus starts in:
Answer
  • pharyngeal and intestinal mucosa
  • blood
  • brain
  • joint

Question 60

Question
In congenital rubella the fetus produce:
Answer
  • IgM
  • IgG
  • lgA
  • lgE

Question 61

Question
The most common classification system used in microbiology is binomal and was established by:
Answer
  • Pasteur
  • Koch
  • Linnaeus
  • Gram

Question 62

Question
Common pili play role in bacterial;
Answer
  • conjugation
  • adherence to surface
  • motility
  • precipitation

Question 63

Question
Endotoxins are:
Answer
  • found in gram (+) bacteria
  • found in gram(-) bacteria
  • proteins
  • a structural component of the spore

Question 64

Question
Which of the following techniques allows to start with a single piece of microbial DNA and produce billions of copies in matter of hour
Answer
  • PCR
  • ELlSA
  • hybridoma biotechnology
  • IFA

Question 65

Question
Which of the following is the fastest way to kill endospores
Answer
  • autoclave at 121*C
  • hot air at 160*C
  • clorox solution
  • filtration

Question 66

Question
Gram positive bacterium is most susceptible to the action of penicillin in the following phase of growth?
Answer
  • lag
  • log
  • stationary
  • decline

Question 67

Question
The primary immune response include participation of?
Answer
  • IgM
  • lgG
  • lgD
  • lgE
  • lgA

Question 68

Question
The first vaccine was used against:
Answer
  • measles
  • tuberculosis
  • hepatitis
  • small pox

Question 69

Question
The alternative pathway of complement activation is:
Answer
  • T lymphocytes dependent
  • antibody independent
  • antibody dependent
  • T lymphocytes independent

Question 70

Question
Which of the immunoglobulins mediates the local immunity
Answer
  • lgA
  • lgM
  • lgG
  • lgD
  • lgE

Question 71

Question
The formation of pharyngeal pseudomembrane is not indicative for
Answer
  • tuberculosis
  • diphtheria
  • whooping
  • gas gangrene

Question 72

Question
The most potent biological toxin known is
Answer
  • clastridiumbotidinum exotoxin
  • staphylococcus aureus enterotoxin
  • bacillus cereus toxin
  • clostridium perfringes exotoxin

Question 73

Question
The special staining method used for microscopic diagnosis of tuberculosis
Answer
  • Gram
  • Klett
  • Ziehl-Neelsen
  • Moller

Question 74

Question
Cytopathic effect is
Answer
  • killing of bacteria by viruses
  • absorption of red blood cells by surface of cultured cells
  • damage of cultured infected cells and associated morphological change
  • antigen-antibody reaction

Question 75

Question
Viruses contain the following type of nucleic acid
Answer
  • DNA-single strained
  • DNA double strained
  • DNA or RNA
  • both DNA and RNA

Question 76

Question
Hepatitis B virus is most often transmitted by
Answer
  • sexual contact
  • air
  • blood transfusion
  • ticks

Question 77

Question
Varicellazinster virus is a member of
Answer
  • hypersnviridae
  • hepadnaviridae
  • retroviridae
  • paenviridae

Question 78

Question
Epstizin Bar Virus is the causative agent of:
Answer
  • measles
  • mumps
  • rubella
  • infectious mononucleosis

Question 79

Question
Sabin's vaccine against poliomyelitis is secretory immunity in the intestine
Answer
  • a killed vaccine
  • a toxoid
  • monovalent hysosome vaccine

Question 80

Question
Spherical bacteria,arranged in cluster are known as:
Answer
  • Staphylococci
  • Streptococci
  • Diplococci
  • Vibrios

Question 81

Question
Which concentration of ethyl alcohol is the most effective one as disinfectant and antiseptic
Answer
  • 95%
  • 70%
  • 50%
  • 30%

Question 82

Question
Penicillin specifically inhibits:
Answer
  • protein synthesis
  • peptidoglyconsynthesis
  • nucleic acid synthesis
  • formation of capsules

Question 83

Question
Conjugation differs from transformation and transduction in that it requires a contact between the donor and the recipient:
Answer
  • True
  • False

Question 84

Question
Which of the following structure is involved in bacterial attachment to cell surface?
Answer
  • capsule
  • flagella
  • pilli
  • measurants

Question 85

Question
Bacterial growth medium that contains penicillins:
Answer
  • minimal medium
  • selective medium
  • differential medium

Question 86

Question
The antigen-antibody complex activates complement through:
Answer
  • classical pathway
  • alternative pathway
  • lectin pathway

Question 87

Question
Complement is
Answer
  • an acute phase protein
  • an extracellular microbial factor
  • a manose receptor
  • multicomponent humeral factor trigger enzyme cascade in innate immunity

Question 88

Question
The unit of measurement of bacterial size is:
Answer
  • nanometer
  • micrometer
  • millimeter
  • kilobase

Question 89

Question
Bacterial growth curve is generally separated into
Answer
  • two distinct phase
  • three distinct phase
  • four distinct phase
  • five distinct phase

Question 90

Question
Resistance to many antibiotics is carried by:
Answer
  • R plasmids
  • sex pilli
  • spores
  • capsules

Question 91

Question
Which of the following structures are known to protect bacteria from phago... by white blood cells
Answer
  • flagella
  • spores
  • capsules
  • ribosomes

Question 92

Question
Spherical bacteria, arranged in chains are known as:
Answer
  • staphylococci
  • streptococci
  • neisseria
  • bacilli

Question 93

Question
Endotoxins are associated with
Answer
  • Catalase production
  • Flagella in gram (-) bacteria
  • LPS (lipopolyshoccharide)
  • Capsules in gram (-) bacteria

Question 94

Question
The antigenic typing of salmonella spp detects:
Answer
  • D, Vi and H antigens
  • Protein
  • M protein
  • Endotoxin

Question 95

Question
Which of the following test is used to detect delayed type hypersensitivity
Answer
  • ASO test
  • CFT
  • Mantoux test
  • None of the above

Question 96

Question
Which are the most important immunoglobulins at the mucosal surfaces
Answer
  • IgA
  • lgM
  • lgD
  • lgG

Question 97

Question
Salmonella spp is causative agent of
Answer
  • typhoid fever
  • cholera
  • paratyphoid fever
  • bacterial dysentery

Question 98

Question
There are animal reservoirs for:
Answer
  • leptosspinosis
  • salmonellosis
  • cholera
  • diphtheria

Question 99

Question
Bacteria could be cultured in artificial nutrient media
Answer
  • True
  • False

Question 100

Question
The mean doubling time for most bacterium is
Answer
  • 8 hours
  • 24 hours
  • 20-30 minutes
  • 4 weeks

Question 101

Question
Dark field microscopy is usually applied for
Answer
  • stained preperations with irreversion cell between cochser
  • unstrained wet preparation with oil between the conduncer and the slide irreverSion
  • unstained wet properations with water between the condenser and the slide
  • ultra thin reactions of tissue

Question 102

Question
The subspecies group are identified on the basis of
Answer
  • arrangement of bacteria preparation
  • gram staining
  • their antigens
  • their growth requirements

Question 103

Question
Which of the following component contain peptidoglycan?
Answer
  • Gram(+) cell walls +F
  • DNA
  • Flagella
  • Cytoplasmic membrane

Question 104

Question
The clorax solution and ethyl alcohol are example of:
Answer
  • sterilizing agents
  • disinfection
  • antibiotics
  • base analogs

Question 105

Question
Which immunoglobin contain j chain
Answer
  • IgA and lgG
  • lgM and lgA
  • lgG and IgM
  • lgD and lgG
  • lgE

Question 106

Question
Which of the following are DNA viruses?
Answer
  • adenoviruses
  • picornviruses
  • paramyxoviruses
  • orthomyoviruses

Question 107

Question
Which one is considered a vireal disease viral
Answer
  • herpes simplex type 1
  • herpes simplex type 2
  • rubella vire
  • medual vire

Question 108

Question
Which of the following diagnostic markers persist in the blood stream of HBV infected individuals and is found an (imcatox) of infection
Answer
  • HBsAg
  • anti-HAV antibodies
  • H-2
  • none of the above

Question 109

Question
All of the following statement about poliomyelitis are correct except:
Answer
  • virus is transmitted mainly in respiratory droplets
  • most disease occur apparent sub-clinical infection
  • persistantviremiafam CNS involvement
  • spinal poliomyelitis involves the anterior born cells of the spinal cord

Question 110

Question
During the incubation period of the HBV infection which of the following viral diagnostic marker is most abundant in blood and is commonly used for diagnosis
Answer
  • HBSAg
  • Anti-HAV antibodies
  • Anti-HCV antibodies

Question 111

Question
Influenza virus on RNA virus:
Answer
  • True
  • False

Question 112

Question
Human herpes virus 2 is usually associated with:
Answer
  • genital herpes
  • measles
  • rubelia
  • erpes zoster

Question 113

Question
Human immunodeficiency virus belongs to:
Answer
  • adenoviridae
  • retroviridae
  • togruviridae
  • poxviridae

Question 114

Question
The presence of low levels lgG but not lgM antibodies to rubella virus in the newborn suggests:
Answer
  • congenital infection
  • autoimmune disease
  • presence of maternal antibodies
  • allergy

Question 115

Question
A four fold or greater increase in autoantibody titer,measured by appropriate available viral diagnostic test and performed on serum collected at time of disease onset and 14 days later would:
Answer
  • be highly suggestive to the presence of the disease
  • indicate previous infection in healthy person
  • not be sufficient for diagnosis
  • not be informative since the serum specimens were not collected at proper interval of time

Question 116

Question
Current acute HAV infection is best diagnosed by the presence of?
Answer
  • HBgcAg
  • anti-HBcsntibodies
  • IgM anti-HAV
  • delta antigen

Question 117

Question
Which of the following microorganisms lack a cell wall
Answer
  • ram positive cocci
  • gram negative rods
  • richetsia
  • mycoplasma

Question 118

Question
All of the following statement are characteristics for group A strepcoccus?
Answer
  • they are rarely resistaned to paraisitis
  • they produce beta-hemolysis on blood agar
  • they are sensitive to bacitracin
  • they are of the normal environment fiera

Question 119

Question
Herpes virus varicella is a member of (zoster) (varicella zoster virus is member of:
Answer
  • herpes viridae
  • poxviridae
  • hepadnaviridae
  • retroviridae

Question 120

Question
Which of the following Viruses cause infection mononucleosis?
Answer
  • Herpes simplex 1
  • Epstein-barr-viruses
  • CMV
  • Varicella zoster virus

Question 121

Question
Type 2 hypersensitivity reactions are
Answer
  • anaphylactic and atopic
  • comlement-mediated cytolysis
  • immune-complexes mediated
  • cell mediated with participation
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