Hematology Diagnostics

Description

Quiz on Hematology Diagnostics, created by lwashing13 on 09/11/2014.
lwashing13
Quiz by lwashing13, updated more than 1 year ago
lwashing13
Created by lwashing13 over 10 years ago
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Resource summary

Question 1

Question
All of the following would decrease WBC levels EXCEPT
Answer
  • trauma
  • immunosuppression
  • drug toxicity
  • overwhelming infection

Question 2

Question
WBC in child < 2
Answer
  • 6,200-17,000
  • 5,000-10,000
  • 9,000-30,000

Question 3

Question
WBC level in >2 to adult
Answer
  • 5,000-10,000
  • 6,200-17,000
  • 9,000-30,000

Question 4

Question
WBC in newborn
Answer
  • 5,000-10,000
  • 6,200-17,000
  • 9,000-30,000

Question 5

Question
What are the panic values for WBC
Answer
  • < 1,000 > 30,000
  • < 2,000 > 30,000
  • < 2,500 > 30,000

Question 6

Question
All of the following are granulocytes EXCEPT
Answer
  • monocytes
  • neutrophils
  • basophils
  • eosinophils

Question 7

Question
T and B cells are part of what type of agranulocyte?
Answer
  • lymphocyte
  • monocyte
  • eosinophil

Question 8

Question
How many days are neutrophils in circulation?
Answer
  • 4
  • 5
  • 6
  • 7

Question 9

Question
Critical value of actual neutrophil count (ANC)
Answer
  • < 1200
  • < 1000
  • < 800

Question 10

Question
Eosinophils are what % of WBC's
Answer
  • 55-70
  • 1-4
  • -.5-1

Question 11

Question
Eosinophils and basophils respond to viral and bacterial infections.
Answer
  • True
  • False

Question 12

Question
Eosinophils and Basophils respond in allergic reactions and parasitic infections
Answer
  • True
  • False

Question 13

Question
What is responsible for hives and skin reactions due to cytoplasm containing heparin, histamine, and serotonin?
Answer
  • neutrophil
  • eosinophil
  • basophil

Question 14

Question
What type of cells provide humoral immunity?
Answer
  • T cells
  • B cells

Question 15

Question
What type of cell produces interferon?
Answer
  • lymphocyte
  • monocyte
  • neutrophil
  • eosinophil

Question 16

Question
All of the following are true for hemoglobin EXCEPT
Answer
  • Transports Oxygen
  • Transports Carbon Dioxide
  • acts as an acid base buffer
  • indicates infection

Question 17

Question
Hemoglobin panic values:
Answer
  • < 10 > 30
  • < 5 > 20
  • < 8 > 15

Question 18

Question
Hematocrit critical value:
Answer
  • < 20 > 60
  • < 15 > 45
  • < 10 > 60

Question 19

Question
MCV
Answer
  • % of hemoglobin in a single RBC (color)
  • Average weight of hemoglobin within a RBC
  • Average volume/size of single RBC

Question 20

Question
Increased reticulocyte means all of the following EXCEPT
Answer
  • bone marrow is putting an increased amount of RBC's into bloodstream
  • hemolytic anemia
  • aplastic anemia
  • SSA

Question 21

Question
Normal or low reticulocyte count with anemia indicates all of the following EXCEPT
Answer
  • hemolysis
  • Marrow is not appropriately responding
  • aplastic
  • Fe deficiency
  • B12 deficiency

Question 22

Question
All would be included in the work-up for macrocytic anemia EXCEPT?
Answer
  • B12 and folate
  • iron studies
  • peripheral smear
  • TSH

Question 23

Question
All would be included in microcytic anemia work-up EXCEPT
Answer
  • iron studies
  • peripheral smear
  • Hgb electrophoresis
  • bone marrow biopsy
  • B12 and folate

Question 24

Question
Iron tells us:
Answer
  • all proteins available for binding to iron
  • the major iron-storage protein
  • quantity of iron bound to transferrin

Question 25

Question
TIBC tells us:
Answer
  • the major iron storage protein
  • quantity of iron bound to transferrin
  • all proteins available for binding to iron

Question 26

Question
What are the iron-binding proteins?
Answer
  • transferrin
  • ferritin

Question 27

Question
What is the major iron-storage protein?
Answer
  • Transferrin
  • Ferritin

Question 28

Question
What is needed for adequate functioning of the RBC's and WBC's due to synthesis of amino acids and DNA?
Answer
  • ferritin
  • folic acid
  • transferrin

Question 29

Question
What does B12 activate?
Answer
  • folate
  • transferrin
  • ferritin

Question 30

Question
The Schilling Test is used for all of the following EXCEPT:
Answer
  • iron deficiency anemia
  • pernicious anemia
  • determine the cause of B12 deficiency

Question 31

Question
Increases LDH, increased bilirubin, and decreased haptoglobin are indicative of:
Answer
  • acute blood loss
  • hemolysis

Question 32

Question
Fetal hemoglobin contains all of the following EXCEPT:
Answer
  • 2 alpha chains
  • 2 beta chains
  • 2 gamma chains

Question 33

Question
What is the most common type of hemoglobin in adults?
Answer
  • A
  • A2
  • F

Question 34

Question
All of the following are found in sickle cell disease except?
Answer
  • D
  • S
  • C

Question 35

Question
What type of hemoglobin doesn't carry oxygen well?
Answer
  • S
  • A
  • F
  • C

Question 36

Question
What type of hemoglobin is found in people of Southeast Asian descent?
Answer
  • C
  • E
  • D

Question 37

Question
HBSS indicates:
Answer
  • inherited 1 sickle cell gene and 1 abnormal hemoglobin gene
  • inherited 2 sickle cell genes
  • inherited 1 sickle cell gene and 1 normal hemoglobin gene

Question 38

Question
HBSC indicates
Answer
  • one sickle cell gene and one abnormal hemoglobin gene
  • 1 sickle cell gene and one normal hemoglobin gene
  • 2 sickle cell genes

Question 39

Question
What test is used to differentiate hemolytic anemia into hereditary spherocytosis or thalassemia?
Answer
  • hemoglobin electrophoresis
  • genetic testing
  • osmotic fragility test

Question 40

Question
Decreased osmotic fragility test indicates:
Answer
  • hereditary spherocytosis
  • thalassemia
  • autoimmune hemolytic anemias

Question 41

Question
What should be suspected in people with hemolysis reactions after certain medications and foods?
Answer
  • G6PD deficiency
  • pernicious anemia
  • hereditary spherocytosis

Question 42

Question
PTT
Answer
  • intrinsic
  • extrinsic

Question 43

Question
All of the following cause prolonged bleeding time EXCEPT
Answer
  • iron deficiency
  • ASA/NSAIDs
  • Von Willebrand
  • scurvy
  • renal failure

Question 44

Question
What is used to monitor heparin therapy
Answer
  • aPTT
  • bleeding time
  • platelet count

Question 45

Question
aPTT/PTT evaluate what pathways?
Answer
  • extrinsic and common coagulation pathways
  • intrinsic and common coagulation pathways
  • intrinsic and extrinsic pathways

Question 46

Question
Warfarin therapy and liver synthetic function is monitored using:
Answer
  • PT/INR
  • aPTT/PTT

Question 47

Question
PT/INR evaluates what pathways?
Answer
  • intrinsic and common
  • extrinsic and common
  • intrinsic and extrinsic

Question 48

Question
Fibrinogen is a measure of what pathway?
Answer
  • intrinsic and common
  • extrinsic and common
  • factor I and common

Question 49

Question
A decrease in antithrombin III leads to
Answer
  • increased bleeding
  • hypercoagulation

Question 50

Question
Protein C inhibits:
Answer
  • Va and VIIIa
  • II, X, XI, XII
  • V, VI, VII

Question 51

Question
Antithrombin III inhibits:
Answer
  • Va, VIIIa
  • II, X, XI, XII
  • V, VI, VII

Question 52

Question
What is the co-factor to Protein C
Answer
  • Protein S
  • antithrombin III
  • factor Va

Question 53

Question
Proteins C and S are decreased in all of the following EXCEPT
Answer
  • Coumadin
  • liver disease
  • renal disease
  • nutritional deficiency

Question 54

Question
C4 binding protein from autoimmune diseases can inactivate:
Answer
  • protein S
  • antithrombin III
  • factor Va

Question 55

Question
What is the most common hereditary coagulation disorder in the US?
Answer
  • Factor V-Leiden
  • sickle cell disease
  • hereditary spherocytosis

Question 56

Question
In Factor V-Leiden, protein C can't break it down which results in all of the following EXCEPT
Answer
  • increased thrombin generation
  • increased antithrombin III generation
  • mild hypercoaguable state

Question 57

Question
APC is a natural anticoagulant that inactivates
Answer
  • X, XII, XI
  • fVa and fVIIIa
  • V, VI, VII

Question 58

Question
patients with factor V leiden will be resistant to WHAT when exposed to APC
Answer
  • deactivation of fVa and fVIIIa
  • activation of fVa and fVIIIa

Question 59

Question
In what disorder is the clotting mechanism inappropriately triggered producing thrombosis and hemorrhage?
Answer
  • Factor V Leidein
  • DIC
  • APC

Question 60

Question
In DIC, fibrin clots form intravascularly consuming platelets and clotting factors leading to what?
Answer
  • decreased bleeding time
  • increased clotting
  • excessive bleeding

Question 61

Question
The following image shows:
Answer
  • sickle cell
  • iron deficiency
  • sideroblastic

Question 62

Question
What is the following smear depicting?
Answer
  • Heinz bodies
  • nucleated RBC's
  • sideroblastic anemia

Question 63

Question
What acts as a carrier protein for factor VIII?
Answer
  • antithrombin III
  • Von Willebrand Factor
  • Hemophilia A

Question 64

Question
What is the most common bleeding disorder?
Answer
  • VWD
  • hemophilia A
  • hemophilia B

Question 65

Question
What is a Factor VIII deficiency?
Answer
  • Hemophilia A
  • Hemophilia B
  • Hemophilia C

Question 66

Question
What is a Factor IX deficiency?
Answer
  • Hemophilia A
  • Hemophilia B

Question 67

Question
Which hemophilia disorder is common among Ashkenazi Jews?
Answer
  • Hemophilia A
  • Hemophilia B
  • Hemophilia C

Question 68

Question
What would be high on your differential with mucosal and cutaneous bleeding?
Answer
  • VWD
  • hemophilia

Question 69

Question
What would be high on your differential with bleeding in joints, muscle, and GI tract?
Answer
  • VWD
  • hemophilia
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