Question 1
Question
All of the following would decrease WBC levels EXCEPT
Answer
-
trauma
-
immunosuppression
-
drug toxicity
-
overwhelming infection
Question 2
Question
WBC in child < 2
Answer
-
6,200-17,000
-
5,000-10,000
-
9,000-30,000
Question 3
Question
WBC level in >2 to adult
Answer
-
5,000-10,000
-
6,200-17,000
-
9,000-30,000
Question 4
Answer
-
5,000-10,000
-
6,200-17,000
-
9,000-30,000
Question 5
Question
What are the panic values for WBC
Answer
-
< 1,000
> 30,000
-
< 2,000
> 30,000
-
< 2,500
> 30,000
Question 6
Question
All of the following are granulocytes EXCEPT
Answer
-
monocytes
-
neutrophils
-
basophils
-
eosinophils
Question 7
Question
T and B cells are part of what type of agranulocyte?
Answer
-
lymphocyte
-
monocyte
-
eosinophil
Question 8
Question
How many days are neutrophils in circulation?
Question 9
Question
Critical value of actual neutrophil count (ANC)
Question 10
Question
Eosinophils are what % of WBC's
Question 11
Question
Eosinophils and basophils respond to viral and bacterial infections.
Question 12
Question
Eosinophils and Basophils respond in allergic reactions and parasitic infections
Question 13
Question
What is responsible for hives and skin reactions due to cytoplasm containing heparin, histamine, and serotonin?
Answer
-
neutrophil
-
eosinophil
-
basophil
Question 14
Question
What type of cells provide humoral immunity?
Question 15
Question
What type of cell produces interferon?
Answer
-
lymphocyte
-
monocyte
-
neutrophil
-
eosinophil
Question 16
Question
All of the following are true for hemoglobin EXCEPT
Question 17
Question
Hemoglobin panic values:
Answer
-
< 10
> 30
-
< 5
> 20
-
< 8
> 15
Question 18
Question
Hematocrit critical value:
Answer
-
< 20
> 60
-
< 15
> 45
-
< 10
> 60
Question 19
Answer
-
% of hemoglobin in a single RBC (color)
-
Average weight of hemoglobin within a RBC
-
Average volume/size of single RBC
Question 20
Question
Increased reticulocyte means all of the following EXCEPT
Question 21
Question
Normal or low reticulocyte count with anemia indicates all of the following EXCEPT
Question 22
Question
All would be included in the work-up for macrocytic anemia EXCEPT?
Answer
-
B12 and folate
-
iron studies
-
peripheral smear
-
TSH
Question 23
Question
All would be included in microcytic anemia work-up EXCEPT
Answer
-
iron studies
-
peripheral smear
-
Hgb electrophoresis
-
bone marrow biopsy
-
B12 and folate
Question 24
Answer
-
all proteins available for binding to iron
-
the major iron-storage protein
-
quantity of iron bound to transferrin
Question 25
Answer
-
the major iron storage protein
-
quantity of iron bound to transferrin
-
all proteins available for binding to iron
Question 26
Question
What are the iron-binding proteins?
Question 27
Question
What is the major iron-storage protein?
Question 28
Question
What is needed for adequate functioning of the RBC's and WBC's due to synthesis of amino acids and DNA?
Answer
-
ferritin
-
folic acid
-
transferrin
Question 29
Question
What does B12 activate?
Answer
-
folate
-
transferrin
-
ferritin
Question 30
Question
The Schilling Test is used for all of the following EXCEPT:
Question 31
Question
Increases LDH, increased bilirubin, and decreased haptoglobin are indicative of:
Answer
-
acute blood loss
-
hemolysis
Question 32
Question
Fetal hemoglobin contains all of the following EXCEPT:
Answer
-
2 alpha chains
-
2 beta chains
-
2 gamma chains
Question 33
Question
What is the most common type of hemoglobin in adults?
Question 34
Question
All of the following are found in sickle cell disease except?
Question 35
Question
What type of hemoglobin doesn't carry oxygen well?
Question 36
Question
What type of hemoglobin is found in people of Southeast Asian descent?
Question 37
Answer
-
inherited 1 sickle cell gene and 1 abnormal hemoglobin gene
-
inherited 2 sickle cell genes
-
inherited 1 sickle cell gene and 1 normal hemoglobin gene
Question 38
Question 39
Question
What test is used to differentiate hemolytic anemia into hereditary spherocytosis or thalassemia?
Question 40
Question
Decreased osmotic fragility test indicates:
Question 41
Question
What should be suspected in people with hemolysis reactions after certain medications and foods?
Answer
-
G6PD deficiency
-
pernicious anemia
-
hereditary spherocytosis
Question 42
Question 43
Question
All of the following cause prolonged bleeding time EXCEPT
Answer
-
iron deficiency
-
ASA/NSAIDs
-
Von Willebrand
-
scurvy
-
renal failure
Question 44
Question
What is used to monitor heparin therapy
Answer
-
aPTT
-
bleeding time
-
platelet count
Question 45
Question
aPTT/PTT evaluate what pathways?
Answer
-
extrinsic and common coagulation pathways
-
intrinsic and common coagulation pathways
-
intrinsic and extrinsic pathways
Question 46
Question
Warfarin therapy and liver synthetic function is monitored using:
Question 47
Question
PT/INR evaluates what pathways?
Answer
-
intrinsic and common
-
extrinsic and common
-
intrinsic and extrinsic
Question 48
Question
Fibrinogen is a measure of what pathway?
Answer
-
intrinsic and common
-
extrinsic and common
-
factor I and common
Question 49
Question
A decrease in antithrombin III leads to
Answer
-
increased bleeding
-
hypercoagulation
Question 50
Question
Protein C inhibits:
Answer
-
Va and VIIIa
-
II, X, XI, XII
-
V, VI, VII
Question 51
Question
Antithrombin III inhibits:
Answer
-
Va, VIIIa
-
II, X, XI, XII
-
V, VI, VII
Question 52
Question
What is the co-factor to Protein C
Answer
-
Protein S
-
antithrombin III
-
factor Va
Question 53
Question
Proteins C and S are decreased in all of the following EXCEPT
Answer
-
Coumadin
-
liver disease
-
renal disease
-
nutritional deficiency
Question 54
Question
C4 binding protein from autoimmune diseases can inactivate:
Answer
-
protein S
-
antithrombin III
-
factor Va
Question 55
Question
What is the most common hereditary coagulation disorder in the US?
Answer
-
Factor V-Leiden
-
sickle cell disease
-
hereditary spherocytosis
Question 56
Question
In Factor V-Leiden, protein C can't break it down which results in all of the following EXCEPT
Answer
-
increased thrombin generation
-
increased antithrombin III generation
-
mild hypercoaguable state
Question 57
Question
APC is a natural anticoagulant that inactivates
Answer
-
X, XII, XI
-
fVa and fVIIIa
-
V, VI, VII
Question 58
Question
patients with factor V leiden will be resistant to WHAT when exposed to APC
Question 59
Question
In what disorder is the clotting mechanism inappropriately triggered producing thrombosis and hemorrhage?
Question 60
Question
In DIC, fibrin clots form intravascularly consuming platelets and clotting factors leading to what?
Answer
-
decreased bleeding time
-
increased clotting
-
excessive bleeding
Question 61
Question
The following image shows:
Answer
-
sickle cell
-
iron deficiency
-
sideroblastic
Question 62
Question
What is the following smear depicting?
Answer
-
Heinz bodies
-
nucleated RBC's
-
sideroblastic anemia
Question 63
Question
What acts as a carrier protein for factor VIII?
Answer
-
antithrombin III
-
Von Willebrand Factor
-
Hemophilia A
Question 64
Question
What is the most common bleeding disorder?
Answer
-
VWD
-
hemophilia A
-
hemophilia B
Question 65
Question
What is a Factor VIII deficiency?
Answer
-
Hemophilia A
-
Hemophilia B
-
Hemophilia C
Question 66
Question
What is a Factor IX deficiency?
Answer
-
Hemophilia A
-
Hemophilia B
Question 67
Question
Which hemophilia disorder is common among Ashkenazi Jews?
Answer
-
Hemophilia A
-
Hemophilia B
-
Hemophilia C
Question 68
Question
What would be high on your differential with mucosal and cutaneous bleeding?
Question 69
Question
What would be high on your differential with bleeding in joints, muscle, and GI tract?