Gentics -RS Q's

Description

So far only Quiz 3,6, 10 and 11 have been added. Not all the questions are added, but most of the quiz.
Rochelle T
Quiz by Rochelle T, updated more than 1 year ago
Rochelle T
Created by Rochelle T about 6 years ago
11
0

Resource summary

Question 1

Question
If a person develops a familial cancer, it is likely that they were born with the gentotype....
Answer
  • -/- in a c-oncogene
  • +/- in a c-oncogene
  • -/- in a TSG
  • +/- in a TSG

Question 2

Question
What is a Roundup Ready transgenic organism?
Answer
  • One that is resistant to insects
  • One that is resistant to herbicides
  • One that is of higher nutritional value
  • One that can withstand the winter Pullman Temps
  • two of the above

Question 3

Question
An individual has a mutation in the proto-oncogene Ras. What type of mutation has likely occured? A. Gain of Function B. Loss of Function C.Recessive D. Dominant
Answer
  • A
  • B and D
  • C
  • D and A

Question 4

Question
Due to this mutation, what is the abnormal function of the mutant Ras? The Ras is [blank_start]continously on[blank_end] (Bound of [blank_start]GTP[blank_end]) because it lots its [blank_start]GDP[blank_end] site (which brings it back down to an [blank_start]inactive state[blank_end]).
Answer
  • continously on
  • GTP
  • GDP
  • inactive state

Question 5

Question
List one of the difference between familial breast cancer and sporadic breast cancer: Familial breast cancer accounts for [blank_start]10%[blank_end] of the cancer developed and sporadic cancer accounts for [blank_start]80%[blank_end] of cancer developed.
Answer
  • 10%
  • 80%

Question 6

Question
Can you manufacture human protein using bacteria? Why or why not? You [blank_start]can[blank_end] with [blank_start]recombinant[blank_end] plasmids, but you need [blank_start]bacteria[blank_end] that has [blank_start]post-translational modifications[blank_end] like in Eukaryotes.
Answer
  • can
  • recombinant
  • bacteria
  • post-translational modifications

Question 7

Question
Gene cloning happens in this order: Purify DNA of interest for ligation Cut vector and ligate in gene Transform recombinant plasmid into competent bacteria Select for transformants
Answer
  • True
  • False

Question 8

Question
What is PCR used for?
Answer
  • To make billions of copies on one DNA sequence
  • To make a few copies of several DNA sequences
  • To destroy a specific DNA sequence

Question 9

Question
Name the three steps of PCR and briefly describe their functions: [blank_start]Denaturation[blank_end]- Break [blank_start]double stranded[blank_end] DNA bonds with heat into [blank_start]single stranded[blank_end] DNA. Add [blank_start]primers[blank_end] [blank_start]Annealing[blank_end]- Seal [blank_start]primers[blank_end] to specific sequence of DNA [blank_start]Extension[blank_end]- Have the [blank_start]Single stranded[blank_end] DNA go through [blank_start]elongation[blank_end] to create a [blank_start]double stranded[blank_end] DNA piece.
Answer
  • Denaturation
  • Annealing
  • Extension
  • double stranded
  • single stranded
  • primers
  • primers
  • Single stranded
  • elongation
  • double stranded

Question 10

Question
There is no issue with PCR. The starting piece of DNA sequence that is selected to be multiplied will always be perfect and therefore, make perfect copies.
Answer
  • True
  • False

Question 11

Question
What is sgRNA?
Answer
  • Signal guide RNA
  • Sequence guide RNA
  • Specific guide RNA

Question 12

Question
What is sgRNA used for in CRISPR-Cas 9?
Answer
  • Cut out the sequences of DNA around our selected piece
  • To guide DNA into the cytoplasm
  • To help read the DNA for Cas-9 to cut at the right sequence

Question 13

Question
What is the result of the following conjugations? F+ x F- = [blank_start]F+[blank_end] + [blank_start]F+[blank_end] Hfr x F- = [blank_start]Hfr[blank_end] + [blank_start]F- recombinant[blank_end]
Answer
  • F+
  • F+
  • Hfr
  • F- recombinant

Question 14

Question
The transfer of naked DNA to a recipient bacterial cell is called
Answer
  • Conjugation
  • Transduction
  • Transformation

Question 15

Question
Naked DNA can be taken up by any nearby bacteria, but requires cell to cell contact between the donor and the recipient.
Answer
  • True
  • False

Question 16

Question
DNA can also be transferred by conjugation, which requires a bacteriophage.
Answer
  • True
  • False

Question 17

Question
Approximately 80% of caner cases arise from germ-line mutation
Answer
  • True
  • False

Question 18

Question
Lederberg and Tatum's work with the autotrophic bacteria demonstrated transduction.
Answer
  • True
  • False

Question 19

Question
R plasmids are a type of F plasmid that can confer antibiotic resistance.
Answer
  • True
  • False

Question 20

Question
Leukemias and lymphnodes are examples of solid tumors
Answer
  • True
  • False

Question 21

Question
Two disease-free parents have a child with Cystic Fibrosis. What is the probability that their next child will be a carrier?
Answer
  • 1/4
  • 1/2
  • 3/4
  • 1
  • Impossible to compute based on this information alone

Question 22

Question
If a genes has 4 alleles in a population, how many different genotypes and phenotypes are possible? Show your work!
Answer
  • 10/ impossible to tell
  • 8/6
  • 20/ impossible to tell
  • 8/4
  • none of the answers are correct

Question 23

Question
Where are the genes for sex-limited traits located?
Answer
  • Autosomes
  • Sex chromosomes
  • only the x chromosome
  • only the y chromosome
  • either on autosome or sex chromosome

Question 24

Question
In incomplete dominance, a likely phenotypic ratio resulting when a heterozygous is selfed in a monohybrid cross would be 3:1.
Answer
  • True
  • False

Question 25

Question
X-chromosome inactivation is important in explaining the unexpected phenotype of females who are homozygous for X-linked genes
Answer
  • True
  • False

Question 26

Question
In an X-linked recessive disease, more males are affected than females.
Answer
  • True
  • False

Question 27

Question
Which type of disease is most commonly embryonic lethal? Choose all that apply
Answer
  • Autosomal recessive
  • Autosomal dominant
  • X-linked recessive
  • X-linked dominant

Question 28

Question
If the GC content of a double stranded DNA molecule is 60%: What is the molar precentage of purines?
Answer
  • 30%
  • 40%
  • 50%
  • 60%

Question 29

Question
If the GC content of a double stranded DNA molecule is 60%: If this were a single stranded DNA molecule, what would the molar precentage of T be?
Answer
  • 30%
  • 15%
  • 25%
  • 60%
  • impossible to tell

Question 30

Question
If a DNA molecule is 150 bp long, what is the approximate length in Angstroms or nm. Choose all that apply
Answer
  • 150 Angstroms
  • 15 nm
  • 51 nm
  • 510 Angstrom

Question 31

Question
Origins of replication are likely found in GC rich regions.
Answer
  • True
  • False

Question 32

Question
In eukaryotes, circular chromosomes have many origins of replication.
Answer
  • True
  • False
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