Question 1
Question
What is the correct statement about the dorsal column?
Answer
-
It is stimulated by crude touch and pressure
-
Receptors on Golgi tendon organ is stimulated within the muscle spindle
-
It is stimulated by pain and temperature
-
Alpha-motoneuron goes to the extrafusal fibers
-
Has two points discrimination
Question 2
Question
Where does neurogenesis take place?
Answer
-
Hippocampus
-
Spinal cord
-
Frontal lobe
-
Cerebellum
-
Thalamus
Question 3
Question
Kluver-Bucy syndrome is:
Answer
-
Lesion of ventral hypothalamus
-
Loss of fear as well as hypersexuality
-
Calmness
-
Increased emotional expression
-
Lesion to hippocampus
Question 4
Question
What is the major role of the astrocytes?
Answer
-
Produce myelination of the axons
-
Protection of neurons and production of enzymatic CSF
-
Support of neural cells
-
Interconnecting the neurons
-
Produce the blood-brain barrier
Question 5
Question
What is the definition of the RP (receptor potential)?
Answer
-
“All or none” principle
-
Amplitude increase with increased intensity of stimulus
-
Frequency increase with increased intensity of stimulus
-
Amplitude decrease with increased intensity of stimulus
-
Frequency decrease with increased intensity of stimulus
Question 6
Question
What is the correct definition of declarative (explicit) memory?
Answer
-
Memory not involving the hippocampus
-
Not associated with consciousness (awareness)
-
Associated with consciousness (awareness)
-
Associated with skills and habits
-
Divided into associative and non-associative learning
Question 7
Question
What structures passes through the medial brainstem?
Answer
-
Cerebral peduncle
-
Reticular formation
-
Dorsal column
-
Substantia nigra
Question 8
Question
What is typical for Alzheimer’s disease?
Answer
-
Remembering new events (short-term memory) and forgetting former events
-
The number of neurons is intact but the mediators for these are destroyed
-
Neurofibrillary tangles inside the neurons caused by hyperphosphorylation of tau
-
Poor long term memory, but intact short term memory
-
Neurons are intact but destruction of synapses
Question 9
Question
Which senses are carried through the dorsal column?
Question 10
Question
The reticular formation:
Answer
-
Controls voluntary movement
-
Controls involuntary movements
-
Controls levels of consciousness
-
Determine whether stimulus is important enough to wake up
-
Is located in the primary motor cortex
Question 11
Question
What is true for mirror neurons?
Answer
-
Implicated in voluntary movement
-
Located in parieto-occipital lobe
-
Fire when observing someone else perform a movement
-
Responsible only for emotion recognition
-
All above are correct
Question 12
Question
Reflex arc of inverse stretch reflex:
Answer
-
Afferent fibers are 1b fibers
-
Contracted muscle contracted, antagonist muscle relaxed
-
Contain four elements
-
Protects the body from injury
-
Is a monosynaptic reflex
Question 13
Question
Which hormones inhibit the hunger center in the brain?
Answer
-
Ghrelin
-
Melanin
-
Neuropeptide Y
-
B-endorphins
-
Leptin
Question 14
Question
The dynamic part of the stretch reflex is responsible for:
Answer
-
Maintaining the muscle tone as a static response
-
Rapid muscle contraction to oppose sudden changes in muscle length
-
Stretching the muscle halfway
-
A weak or slow muscle contraction
-
Rapid response due to changes in primary endings on nuclear chain fibers
Question 15
Question
Neurotrophins are:
Answer
-
Produced by neurons during neuron degeneration
-
Proteins produced by glial cells and inflammatory cells
-
Large proteins that maintain function and growth of neurons
-
Cannot induce differentiation of progenitor cells to form neurons
-
Secreted predominantly outside the target tissues
Question 16
Question
What is a function of the cerebellum?
Answer
-
Detect fine touch and pressure
-
Process sensory information from the periphery
-
Process information from thermoreceptors
-
Process and send signals to regulate movement
-
Takes part in the direct pathway of voluntary movement
Question 17
Question
What is the function of intrafusal fibers?
Answer
-
Detect change in length of extrafusal fibers
-
Transmit signals via alpha fibers
-
Have no important role in the muscle contraction
-
Responsible for contractibility of a muscle
-
Make up a large amount of skeletal (striated) muscle
Question 18
Question
Pyramidal tract transmits through:
Answer
-
Alpha motoneuron
-
Gamma motoneuron
-
Intermediate neuron
-
Sensory neuron
-
Inhibitory interneuron
Question 19
Question
REM sleep is referred with:
Answer
-
Sleep where memories can be remembered during
-
Sleep where dreams cannot be recalled
-
Deep, restful sleep
-
Increased muscle tone and decreased heart rate
-
Eye movement are at a minimum
Question 20
Question
Hormones that excite satiety (feeling full) is:
Answer
-
Leptin, Ghrelin, POMC, CART
-
Leptin, CCK, POMC, Oxytocin
-
Neuropeptide Y, Orexins A and B, Melanin
-
B-endorphins, CCK, CRH, Oxytocin, Leptin
-
Neuropeptide Y, Glucagon, GLP-1, GLP-2
Question 21
Question
Things that activate cold receptors (things that make you hot) are:
Question 22
Question
The amygdaloidal body is responsible for:
Answer
-
Skills and habits
-
Endocrine system
-
Creating negative feelings like rage and fear
-
Controlling the pain gate system
-
Creating positive feelings like euphoria
Question 23
Question
Which statement about cerebrospinal fluid (CSF) is correct?
Answer
-
It is absorbed by the choroid plexus
-
Its absorption is independent of CSF pressure
-
It circulates in the epidural space
-
It has a lower glucose concentration than plasma
-
It has a higher protein concentration than plasma
Question 24
Question
Which statement about REM sleep is correct?
Answer
-
Is also called paradoxical sleep
-
Regular EEG waves
-
Dreams cannot be recalled
-
Decreased heart rate and respiration
-
REM sleep duration decreases with each sleep cycle
Question 25
Question
The reward system is connected with:
Question 26
Answer
-
Glutamate and Substance P close the gate
-
Is independent on enkephalinergic system
-
Is independent on endorphin system
-
Enkephalin close the pain gate in the spinal cord
-
Is closed by both non-painful input and painful input
Question 27
Question
Conditioned reflexes are evoked under which conditions?
Answer
-
Unconditioned stimulus repeated many times
-
Conditioned stimulus repeated many times
-
Unconditioned and conditioned stimulus paired many times
-
Conditioned stimulus present enough without unconditioned stimulus
-
An external input is present
Question 28
Question
Which of the following statements about the prefrontal, association area is correct?
Answer
-
Planning of voluntary movement and prediction
-
Area for language comprehension
-
Area for visual language (reading)
-
Role in behavior, emotions and motivation
-
Analysis of spatial coordination
Question 29
Question
Lesion to the upper motor neurons leads to?
Answer
-
Decreased reflexes
-
Spasticity
-
Flaccid paralysis
-
Negative Babinski sign
-
Decreased muscle tone
-
Oscillation of muscles
Question 30
Question
Parkinson’s disease:
Answer
-
Degeneration of dopaminergic neurons in substantia nigra
-
Symptoms include rigidity and decreased muscle tone
-
Loss of cholinergic receptors
-
Rapid movements
-
Repeat of trinucleotide CAG on chromosome 4
Question 31
Question
What is correct about cerebellum?
Answer
-
It compares movement intended with actual movements
-
It controls posture and equilibrium
-
Lesion leads to hypertonicity
-
Control muscle contraction
-
All answers are correct
Question 32
Answer
-
Initiate movements
-
Directly stimulate thalamus
-
Controls levels of consciousness
-
“Decodes” the sensory signals
-
Regulation of muscle tone and spinal reflexes
Question 33
Question
Lesion to upper margin of pons will:
Answer
-
Change the regulation of brain activity
-
Result in loss of consciousness
-
Effect the reticular activation system
-
Increase muscle tone by increased signals to gamma motoneurons
-
Decreased muscle tone by increased signals to gamma motoneurons
Question 34
Question
Which is true concerning delta waves in EEG?
Answer
-
Appear at consciousness
-
Could be registered selectively from hippocampus
-
Appear in deep sleep
-
Represent sleep spindles
-
Are characterized by high amplitude and high frequency
-
Are characterized by low amplitude and high frequency
Question 35
Question
Which statement regarding REM sleep is correct?
Answer
-
Constitutes of 4 stages
-
Is characterized by sleep spindles
-
Is important for consolidation of memory
-
Is characterized by increased muscle tone and theta waves
-
In adults occupies 80% of whole sleep
Question 36
Question
During voluntary movement, the golgi tendon organ provides the central nervous system with information about:
Answer
-
The length of the muscle being moved
-
The velocity of the movement
-
The blood flow to the muscle being moved
-
The tension developed by the muscle being moved
-
The change in joint angle produced by the movement
Question 37
Question
Repetitive stimulation of a skeletal muscle fiber will cause an increased contractile strength because repetitive stimulation causes an increase in:
Answer
-
The duration of cross bridge cycling
-
The concentration of calcium in the sarcoplasm
-
The magnitude of the end plate potential
-
The number of muscle myofibrils generating tension
-
The velocity of the muscle contraction
Question 38
Question
Conduction aphasia is likely to be associated with a lesion of the:
Answer
-
Wernicke’s area 22
-
Parietal lobe
-
Frontal lobe
-
Arcuate fasciculus
-
Corticospinal tract
Question 39
Question
Most important role of gamma-motoneurons is to:
Answer
-
Stimulate skeletal muscle fibers to contract
-
Maintain Ia afferent activity during contraction of muscle
-
Generate activity in Ib afferent fibers
-
Detect the length of resting skeletal muscle
-
Prevent muscles from producing too much force
Question 40
Question
Transmission through the anterolateral pathway ultimately ends up in the:
Answer
-
Primary motor cortex
-
Premotor cortex
-
Supplementary motor cortex
-
Somatosensory cortex SI and SII
-
Posterior parietal cortex
Question 41
Question
Kluver-Bucy syndrome will give what symptoms?
Question 42
Question
Final common pathway is another term for?
Answer
-
Higher motor neurons
-
Lower motor neurons
-
Effector organs
-
Integration center
-
Renshaw cells
Question 43
Question
Role of mirror neurons?
Answer
-
Fire when performing a voluntary task
-
Activated when watching someone perform ask
-
Is responsible for emotion recognition in other people
-
Can be found in the frontal or parietal lobe
-
All are correct
Question 44
Question
What characterizes alpha waves?
Answer
-
Have the highest frequency waves
-
They appear when studying for a test
-
They appear when you close your eyes
-
They appear only during deep sleep
-
They appear when awake and open eyes
Question 45
Question
What is the main reason for Huntington’s disease?
Answer
-
Loss of dopaminergic neurons in the substantia nigra
-
Repeat of trinucleotide CAG on chromosome 5
-
Repeat of trinucleotide CAT on chromosome 4
-
Increased Cholinergic and GABA release
-
Decrease in GABAergic and cholinergic release
Question 46
Question
An abnormal Babinski reflex indicates damage to the:
Answer
-
Spinal cord
-
Brainstem
-
Cerebellum
-
Basal ganglia
-
Pyramids
Question 47
Question
Which fibers contract in the myotatic reflex?
Answer
-
Extrafusal muscle fibers
-
Intrafusal muscle fibers
-
Nuclear bag fibers
-
Nuclear chain fibers
-
Alpha fibers
Question 48
Question
What is the name of the phenomenon of “referred pain”?
Answer
-
Hyperalgesia
-
Dermatome theory
-
Alternate theory
-
Facilitation
-
Stereognosis
Question 49
Question
Which part of the brain is responsible for mathematical calculation and fact numbers?
Answer
-
Frontal and occipital
-
Frontal and parietal
-
Temporal and frontal
-
Temporal and parietal
-
Parietal and occipital
Question 50
Question
Lesion to upper motor neuron:
Question 51
Question
All of the following are symptoms of cerebellar lesion except:
Answer
-
Rigidity
-
Nystagmus
-
Ataxia
-
Adiadochokinesia
-
Intention tremor
Question 52
Question
The majority of fibers from the thalamus goes toward the:
Question 53
Question
Which structure is not at the level of the medulla oblongata?
Answer
-
Cuneate nucleus
-
Abducent nucleus
-
Red nucleus
-
Facial nucleus
-
Reticular formation
Question 54
Question
What are the steps involved in the inverse stretch reflex?
Answer
-
Golgi tendon monosynaptic pathway contracted muscle stretched and antagonist muscle relaxed
-
Free nerve endings polysynaptic pathway inhibition of extensor and stimulation of flexor
-
Muscle spindle monosynaptic pathway extrafusal muscle fibers are stimulated
-
Golgi tendon disynaptic pathway contracted muscle relaxed and antagonist muscle contracted
Question 55
Question
Left hemisphere lesion is mainly responsible for:
Answer
-
Good feelings such as euphoria
-
Language disorder and depression
-
Loss of visualization of shapes and vision
-
Loss of sensation from the left side of the body
-
Less identification of form of objects and faces
Question 56
Question
Which of the following hypothalamic nuclei is responsible for controlling the normal circadian rhythm?
Answer
-
Paraventricular nucleus
-
Ventromedial nucleus
-
Arcuate nucleus
-
Lateral nucleus
-
Suprachiasmatic nucleus
Question 57
Question
Decerebrate rigidity:
Answer
-
Happens during Parkinson’s disease, when reduced inhibition by dopamine causes excitation of vestibular nuclei
-
Transsection of the brain stem at the medulla oblongata
-
Will cause increased muscle tone
-
Happens when descending signals to gamma motoneurons is increased which increases muscle tone
-
Is due to lesion of the upper pons and increased sensory sensitivity
Question 58
Question
Neurogenesis means:
Answer
-
That stem cells in the olfactory bulb can grow into new nerve cells
-
That stem cells in the hippocampus are involved in memory
-
That neurons are produced by neural stem cells
-
Glial cells can be produced and some new cells go through apoptosis
-
All correct
Question 59
Question
Which of the following statements is correct regarding neurotrophins?
Answer
-
NGF attaching to p75NT and Trk A prevents apoptosis
-
NGF attaching to p75NT and Trk A promotes cell survival
-
Neurotrophins are transported back from target nucleus by anterograde transport
-
Neurotrophins belongs to a large protein family
-
Neurotrophic receptors can be either p65 or Trk family
Question 60
Question
Plasticity means:
Answer
-
Topographical representation changes with experience
-
Sensory neurons to cortex can change with usage
-
Functions of different parts can change as needed
-
Sensory unit connections to cerebral cortex stays the same without use
-
Synaptic receptors become more sensitive
Question 61
Question
Cutting which of the following fibers can cause spastic paralysis?
Answer
-
Corticospinal fibers
-
Vestibulospinal fibers
-
Reticulospinal fibers
-
Spinothalamic fibers
-
Ia afferent fibers
-
Corticoreticular fibers
Question 62
Question
The center of the reward system is the:
Answer
-
Ventral tegmentum
-
Dorsal brain stem
-
Nucleus accumbens
-
Posterior hypothalamus
-
Dorsal midbrain
Question 63
Question
The sympathetic system involves:
Question 64
Question
What is true about operant conditioning?
Answer
-
Discovered by Ivan Pavlov
-
Involve reward and punishment
-
The animal can learn from looking at other animal’s behavior
-
Animal learns skills by habituation
-
Is a type of non-associative learning
Question 65
Question
Mass reflex can involve the following symptom:
Answer
-
Hypotonicity
-
Dysdiadochokinesia
-
Two-point discrimination
-
Profuse sweating
-
None of the above
Question 66
Question
Where does neurogenesis take place?
Answer
-
Hippocampus
-
Spinal cord
-
Frontal lobe
-
Cerebellum
Question 67
Question
The role of the intrafusal fibers:
Answer
-
Located in the tendon, together with the tendon organ
-
Stretch of the central part of the muscle spindle following stimulation of gamma motoneurons
-
Innervated by alpha and contracted following stimulation of these neurons
-
Stimulated together with extrafusal muscle fibers
-
Only make up nuclear bag fibers
Question 68
Question
The major role of oligodendrocytes in the body is:
Answer
-
Absorption of CSF
-
Protection of nerves
-
Blood-brain barrier
-
Nourishment
-
None of the mentioned
Question 69
Question
Mass reflex can involve which of the following?
Answer
-
Loss of muscle tone
-
Rigidity
-
Muscle hypotrophy
-
Incontinence of urine
-
None of the mentioned
Question 70
Question
Referred pain is caused by:
Answer
-
Stereognosis
-
Facilitation
-
Hyperalgesia
-
Same dermatome origin
-
None of the mentioned
Question 71
Question
What does the anterolateral pathway transmit?
Answer
-
Fine touch sensation
-
Crude touch and temperature
-
Sensation from two points at once
-
Vibration and pressure sensation
-
Kinesthesia sensation
Question 72
Question
What is characteristic for transmission in the anterolateral pathway?
Answer
-
High velocity
-
Only temperature and pain is transmitted
-
Precise localization of sensation
-
Highly discrete localization is not required
-
Large, myelinated fibers
Question 73
Question
The precentral gyrus and corticospinal tract are essential for:
Answer
-
Vision
-
Olfaction
-
Auditory identification
-
Kinesthesia
-
Voluntary movement
Question 74
Question
During normal voluntary movement:
Answer
-
Large muscle fibers are recruited before small muscle fibers
-
Fast muscle fibers are recruited before slow muscle fibers
-
Weak muscle fibers are recruited before strong muscle fibers
-
Poorly perfused muscle fibers are recruited before richly perfused muscle fibers
-
Anaerobic fibers are recruited before aerobic fibers
Question 75
Question
Norepinephrine will cause the contraction of the smooth muscle in the:
Answer
-
Bronchioles
-
Arterioles
-
Pupils
-
Intestine
-
Ciliary body
Question 76
Question
The alpha rhythm appearing on an electroencephalogram has which of the following characteristics?
Answer
-
It produces 20 to 30 waves per second
-
It is replaced by slower, larger waves during REM sleep
-
It represents activity that is most pronounced in the frontal region of the brain
-
It disappears when patient’s eyes open
-
It is associated with deep sleep
Question 77
Question
Correct statement regarding rapid eye movement (REM) sleep include which of the following?
Answer
-
It is the first stage of sleep entered when a person falls asleep
-
It is accompanied by loss of skeletal muscle tone
-
It is characterized by a slow but steady heart rate
-
It occurs more often in adults than in children
-
It lasts longer than periods of slow-wave sleep
Question 78
Question
What nerve fibers transmit the thermal stimulus of heat and cold?
Question 79
Question
Reticular formation of brain stem is in charge of:
Answer
-
O2 consumption, respiration, temperature, circadian rhythm
-
Osmolarity, volume of extracellular fluid, glucose, appetite
-
Sequencing of movement, spatial-temporal relation
-
Secretion of glucocorticoids, catecholamines, dopamine, vasopressin
-
Heart rate, vasodilation, vasoconstriction, swallowing
Question 80
Question
Stimulation input from descending part of the reticular formation is known to produce:
Answer
-
Contraction of IF, contraction of SM
-
Stretch of IF, relaxation of SM
-
Stimulation of GP, relaxation of SM
-
Relaxation of IF, contraction of SM
-
Stretch of IF, contraction of SM
Question 81
Question
Which receptor is connected with addiction?
Answer
-
D2 receptors
-
D3 receptors
-
5HT2 receptors
-
5-HT receptors
-
Serotonin receptors
Question 82
Question
Lesion to what causes past-pointing, drunken and intention tremor?
Answer
-
Cerebellum
-
Thalamus
-
Hypothalamus
-
Precentral gyrus
-
Neocortex
Question 83
Question
Hyperkinetic disorder symptoms:
Answer
-
Akinesia
-
Ballism
-
Bradykinesia
-
Adiadochokinesia
-
Intention tremor
Question 84
Question
Plasticity as a symptom include:
Answer
-
Decreased muscle tone
-
Increased muscle tone
-
Abnormal absence of movement
-
Purposeless contractions that produce shaking
-
Resistance to passive stretch
Question 85
Question
Facilitation as a symptom include:
Question 86
Question
Increased activity of the SNS causes:
Question 87
Question
Presynaptic inhibition in the CNS affects the firing rate of alpha motoneurons by:
Answer
-
Increasing the chloride permeability of the presynaptic nerve ending
-
Decreasing the potassium permeability of the alpha motoneuron
-
Decreasing the frequency of action potentials by the presynaptic nerve ending
-
Increasing (hyperpolarizing) the membrane potential of the alpha motoneuron
-
Increasing the amount of neurotransmitter released by the presynaptic nerve ending
Question 88
Question
Adrenergic receptors located in the heart are types of:
Answer
-
M2 receptors
-
M3 receptors
-
Beta-1 receptors
-
Alpha-1 receptors
-
Alpha-2 receptors
Question 89
Question
An aphasia is most likely to be associated with a lesion of:
Answer
-
The hippocampus
-
The parietal lobe
-
The temporal lobe
-
The limbic system
-
The reticular formation
Question 90
Question
RAS is responsible for the following except:
Answer
-
Pain
-
Visual
-
Olfactory
-
Consciousness
-
Speech
Question 91
Question
Increased activity of the PNS causes:
Answer
-
Increased heart rate
-
Pupil constriction
-
Bronchiolar dilation
-
Ciliary muscle dilation
-
Increased sweating
Question 92
Question
Flexor withdrawal reflex is:
Answer
-
Responsible for monosynaptic excitation of ipsilateral homonymous muscle
-
Responsible for polysynaptic excitation of contralateral extensors
-
The same as inverse myotatic reflex
-
Responsible for increase in gamma-motoneuron activity
-
Responsible for disynaptic inhibition of ipsilateral extensors
Question 93
Question
Autogenic inhibition is related to:
Answer
-
Ia fibers in muscle spindle
-
Ib fibers in golgi tendon
-
Type II (A-beta fibers)
-
Type III (A-delta fibers)
-
C-fibers
Question 94
Question
Lesion of UMN leads to:
Question 95
Question
Lesion of LMN leads to:
Question 96
Question
Which pathway is a descending efferent pathway?
Answer
-
Dorsal column medial lemniscal pathway
-
Anterior corticospinal tract
-
Anterior spinothalamic tract
-
Lateral spinothalamic tract
-
Posterior spinocerebellar tract
Question 97
Question
Free nerve endings contain receptors that encode the sensation of:
Answer
-
Fine touch
-
Vibration
-
Pressure
-
Temperature
-
Muscle length
Question 98
Question
Which pathway is an ascending afferent pathway?
Answer
-
Lateral spinothalamic tract
-
Lateral corticospinal tract
-
Anterior corticospinal tract
-
Reticulospinal tract
-
Vestibulospinal tract
Question 99
Question
Which one of the following hypothalamic nuclei is responsible for the detection of the core body temperature?
Question 100
Question
The sympathetic response in a “fight or flight” reaction causes a decrease in:
Answer
-
The arterial blood pressure
-
The diameter of the pupil
-
The resistance of the airways
-
The heart rate
-
The blood glucose concentration