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Infectious Diseases Final MCQs- 5th Year PMU

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Infectious Diseases Final MCQs- 5th Year PMU
Med Student
Quiz by Med Student , updated more than 1 year ago
Med Student
Created by Med Student almost 5 years ago
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Question 1

Question
The specific CNS complication of Chickenpox is
Answer
  • cerebellitis
  • meningitis serosa
  • polyradiculoneuritis - Guillain-Barre

Question 2

Question
Treatment of cerebral oedema includes
Answer
  • Diuretics – spironolactone
  • Diuretics – mannitol, furanthril
  • Non-steroidal anti-inflammatory drugs

Question 3

Question
Common presentations of AIDS are
Answer
  • prolong morning low grade fever, weight loss, diarrhea
  • hyperpyrexia with profuse sweating, dehydration with metabolic changes
  • bulimia, hyperactivity, psychomotor agitation

Question 4

Question
Which meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, normal or slightly elevated protein and normal glucose level?
Answer
  • Viral
  • Purulent
  • Tuberculous

Question 5

Question
The rash in Scarlet fever is
Answer
  • maculo-papules, vesicular, different stages at the same time
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Question 6

Question
Typical for Diptheria are
Answer
  • dense, dirty gray, hard deposits on the tonsils
  • whitish deposits on the tonsils and buccal mucosa, easily removable
  • the disease is widespread in Bulgaria

Question 7

Question
The most common clinical manifestation of Salmonellosis is
Answer
  • sepsis
  • cholecystitis
  • gastroenteritis

Question 8

Question
Which is the antibiotic of choice of for Mediterranean spotted fever
Answer
  • Gentamycin
  • Doxycycline
  • Ceftriaxone

Question 9

Question
Poliomyelitis is characterised by
Answer
  • flaccid asymmetric, proximal paralysis
  • flaccid symmetric, proximal paralysis
  • full recovery of the affected limb

Question 10

Question
Typical for clinical presentation of Cholera is
Answer
  • rigor and high fever
  • ‘rice water’ stools
  • persistent vomiting, severe stomach pain

Question 11

Question
The agent of which disease has teratogenic effect?
Answer
  • Rubella
  • Scarlet fever
  • Measles

Question 12

Question
The main factor for chronicity in HBV infection is
Answer
  • age
  • innate immunity
  • gender

Question 13

Question
The diarrheal syndrome in shigellosis is characterised with
Answer
  • large amount of watery stools + abdominal pain
  • sparse, bloody mucoid stools + tenesmi
  • voluminous liquid, ” rice water” type stools

Question 14

Question
Hepatitis with the most severe course with possibility of acute liver failure is
Answer
  • acute hepatitis C
  • acute hepatitis B+ hepatitis D
  • viral hepatitis E
  • viral hepatitis A

Question 15

Question
Which infection is vaccine preventable
Answer
  • Salmonella
  • Measles
  • Scarlet fever

Question 16

Question
Hypopotassemia may be suspected in a patient with
Answer
  • enhanced motility and spastic colon
  • intestinal paresis and bloated abdomen
  • generalized seizures

Question 17

Question
Empirical therapy for bacterial meningitis includes
Answer
  • 3rd generation Cephalosporins + Vancomycin
  • Penicillin + Metronidazole
  • 3rd generation Cephalosporins + Clindamycin

Question 18

Question
Measles rash appears
Answer
  • 24 h after onset of the disease
  • the disease begins with it
  • on 3-5-the day of disease onset

Question 19

Question
The stools in cholera resemble
Answer
  • rice water
  • sputum with mucus, blood and pus
  • raspberry jelly

Question 20

Question
The most common causative agents of purulent meningitis are
Answer
  • S.pneumoniae, N. meningitidis, H. influenzae
  • S.pneumoniae, Staph.aureus, Myc. tuberculosis
  • N meningitidis, L. monocytogenes, St. epidermidis

Question 21

Question
The rash of Chicken pox is
Answer
  • maculo-papules, vesicular, different stages at the same time
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Question 22

Question
Who is NOT at risk for severe Chickenpox
Answer
  • persons with cellular immunodeficiency
  • pregnant
  • children aged 2-6

Question 23

Question
The earliest laboratory test for confirmation of acute hepatitis C is
Answer
  • Anti-HCV by ELISA
  • HCV RNA by PCR
  • HCV Ag by ELISA

Question 24

Question
Pregnant in the 1st trimester has discrete macular rash and negative serological test (ELISA) for Rubella. What is the next step?
Answer
  • Therapeutic abortion
  • Ribavirin therapy
  • Repeating the test after 3 weeks

Question 25

Question
Shigellosis is likely to present with seizures in
Answer
  • elderly people
  • children under the age of 3 years
  • such onset is unlikely

Question 26

Question
Which test is best to confirm EBV as causative agent of infectious mononucleosis
Answer
  • detection of heterophile antibodies
  • detection of specific antibodies to EBV
  • detection of nucleic acid of EBV in the blood

Question 27

Question
Raspberry tongue is typical for
Answer
  • Scarlet fever
  • Measles
  • Chickenpox

Question 28

Question
The most common neoplasm in HIV infection is
Answer
  • Kaposki‘s sarcoma
  • Pulmonary carcinoma
  • Melanoma

Question 29

Question
The aminotransferases (ALT and AST) in acute viral hepatitis are
Answer
  • Normal
  • 100 E/L
  • > 1000 E/l

Question 30

Question
Etiological treatment of choice in cholera is
Answer
  • penicillin
  • cephalosporin 4-th generation
  • tetracycline

Question 31

Question
Antibiotic of choice for the treatment of Scarlet fever is
Answer
  • tetracycline
  • penicillin / beta-lactam
  • gentamicin

Question 32

Question
Meningeal irritation includes
Answer
  • nuchal rigidity, hyperesthesia
  • diminished tendon reflexes
  • altered mental status

Question 33

Question
Route of transmission in Lyme disease is
Answer
  • via tick bite
  • via drinking unpasteurized milk
  • via mosquito bites

Question 34

Question
The most common causative agent of pneumonia in AIDS patients is
Answer
  • Mycoplasma pneumoniae
  • Pneumocystis jiroveci (carinii)
  • Hantavirus

Question 35

Question
Typical clinical manifestation of tetanus is
Answer
  • confusion
  • periodic muscle rigidity
  • permanent muscle rigidity and periodic seizures

Question 36

Question
Antibiotic of choice for treatment of Erythema migrans is
Answer
  • Cefrtiaxone
  • Doxycycline
  • Gentamycine

Question 37

Question
Measles rash
Answer
  • appears after 24 h after the disease onset
  • the disease starts with it
  • appears on 3-5th day of disease onset

Question 38

Question
At risk of acute viral hepatitis C are
Answer
  • intravenous drug abusers
  • newborns in poor sanitary conditions
  • travellers to tropical countries

Question 39

Question
The rash of meningococcemia is
Answer
  • hemorrhagic necrotic, localized predominantly on the lower limbs and buttocks
  • vesicular, diffuse
  • vesicular, highly pruritic

Question 40

Question
Initial treatment of infectious diarrhea includes
Answer
  • rehydration
  • antibiotic
  • correction of ↓K

Question 41

Question
On suspicion of acute viral hepatitis the minimum laboratory TESTS are
Answer
  • alkaline phosphate, gamma glutamyl transferase
  • urine (bile pigments), serum (ALT and AST, bilirubin)
  • complete blood count, electrolytes, acid-base metabolism

Question 42

Question
The evolution of Chickenpox rash is
Answer
  • macula – papule - vesicle - crust
  • macula- papule - brown pigmentation
  • petechiae- ecchymosis- suffusion

Question 43

Question
The main factor for chronicity in HBV infection is
Answer
  • age
  • innate immunity
  • gender

Question 44

Question
The mainstay of diphtheria treatment is
Answer
  • antibiotics
  • antitoxin serum
  • corticosteroids

Question 45

Question
Which infection is vaccine-preventable
Answer
  • Measles
  • Scarlet fever
  • Lyme borreliosis

Question 46

Question
Koplik spots are pathognomonic sign for
Answer
  • Scarlet fever
  • Measles
  • Rubella

Question 47

Question
Jaundice as a clinical manifestation of acute viral hepatitis C is seen
Answer
  • in a few patients
  • in the majority of patients
  • in about half of the cases

Question 48

Question
Laboratory minimum for suspected viral hepatitis is
Answer
  • urine (bile pigments), serum (ALT and AST, bilirubin)
  • CBC, electrolytes, acid-base balance
  • abdominal ultrasound

Question 49

Question
Meningeal irritation, prolonged clouding consciousness and focal neurological findings are common in
Answer
  • meningoencephalitis
  • encephalitis
  • meningitis

Question 50

Question
The incubation period in Shigellosis is
Answer
  • 2 weeks
  • 1-7 days
  • 4-6 hours

Question 51

Question
What type of toxin is released by Salmonella bacteria on cell lysis
Answer
  • endotoxin
  • neurotoxin
  • enterotoxin

Question 52

Question
Which of the following agents causes hemolytic-uremic syndrome
Answer
  • enterohemorrhagic E.coli
  • enteroinvasive E.coli
  • pathogenic E.coli

Question 53

Question
The agent of which disease has teratogenic effect?
Answer
  • Rubella
  • Scarlet fever
  • Measles

Question 54

Question
Which of the following statements regarding enteroviruses as causative agents of aseptic meningitis are NOT TRUE?
Answer
  • Enteroviruses account for up to 80% of cases of viral meningitis.in children
  • the clinical presentation in children is milder than in adults
  • lymphocytes are predominant in the first 24 hours, later neutrophils prevail

Question 55

Question
Which type of immunity is impaired in HIV infection?
Answer
  • humoral
  • cell mediated
  • innate

Question 56

Question
Viral hepatitis A is transmitted via
Answer
  • fecal-oral mechanism
  • parenteral mechanism
  • sexual mechanism

Question 57

Question
The most common causative agent of of Infectious mononucleosis is
Answer
  • Epstein-Barr virus
  • Cytomegalovirus
  • HIV

Question 58

Question
The main route of transmission of hepatitis C virus is
Answer
  • fecal-oral
  • intravenous usage
  • sexual

Question 59

Question
The rash in Scarlet fever is ???
Answer
  • maculo-papules, vesicular, fast evolution of stages
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Question 60

Question
The mental status in tetanus is
Answer
  • blurred
  • alert
  • hallucinations are typical

Question 61

Question
Typical Measles rash is
Answer
  • maculo-papular rash appearing on the first day of the disease
  • maculo-papular rash, confluent, appears on the 4-5 the day
  • discrete maculo-papular rash fades after 3 days

Question 62

Question
Which type of meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, elevated protein and decreased glucose level
Answer
  • viral
  • purulent
  • tuberculous

Question 63

Question
Which of the following conditions are NOT AIDS-defining illness?
Answer
  • Herpes zoster
  • Kaposki’s sarcoma
  • Esophageal candidiasis

Question 64

Question
Cholera initially presents with
Answer
  • chills and high fever
  • diarrhea ” rice water” type
  • intractable vomiting

Question 65

Question
Which of the following microorganisms is associated with diarrhoea after antibiotic therapy or severe operations
Answer
  • Cl. difficile
  • Salmonella
  • E.coli

Question 66

Question
Diarrheal syndrome in shigellosis is characterised by
Answer
  • large amount of watery stools + abdominal pain
  • sparse, bloody mucoid stools + tenesmi
  • voluminous liquid, ” rice water” type stools

Question 67

Question
A pregnant woman in first trimester had contact with a sick child, suspected to have rubella. How could you manage her
Answer
  • to clarify if the child has Rubella
  • to recommend abortion on medical grounds
  • to determine her immunity by serology

Question 68

Question
The most common presentation of Lyme borreliosis is
Answer
  • erythema migrans
  • arthritis
  • neuritis

Question 69

Question
The most common initial complaints in acute viral hepatitis are
Answer
  • fatigue, anorexia, nausea, loss of appetite
  • severe abdominal pain radiating to the shoulders and vomiting
  • fever and diarrhoea

Question 70

Question
First choice antibiotic for treatment of pertussis is
Answer
  • ceftriaxone
  • macrolides
  • amikacin

Question 71

Question
Empirical treatment on suspicion of bacterial meningitis includes
Answer
  • 3rd generation Cephalosporins + Vancomycin
  • Penicillin + Metronidazole
  • 3rd generation Cephalosporins + Clindamycin

Question 72

Question
Thick pseudomembrans, spreading across the pharyngeal mucosa and bleeding while dislodging, are characteristic for
Answer
  • mononucleosis
  • diphtheria
  • strepto pharyngitis

Question 73

Question
Pustula maligna is typical for
Answer
  • Anthrax
  • Mediterranean spotted fever
  • Tularemia

Question 74

Question
Anthrax infection results from
Answer
  • exposure to cattle and goats
  • tick bite
  • mosquito bite

Question 75

Question
Acute hepatitis C becomes chronic in
Answer
  • 30-80%
  • < 2%
  • >90%

Question 76

Question
The stages in the course of HIV/AIDS infection are
Answer
  • early HIV infection, latency period, AIDS
  • catarrhal period , rash period , convalescent period
  • initial intoxication period, period of generalized lymphnodulomegaly, period of hepatosplenomegaly

Question 77

Question
Serological markers of acute viral hepatitis B are
Answer
  • HBsAg (+) and anti HBc IgM (+)
  • HBsAg (+) and anti HBc total (+)
  • anti HBsAg (+) and anti HAV IgM (+)

Question 78

Question
Arthralgia in acute viral hepatitis presents with
Answer
  • joint pain without swelling and redness
  • swelling, redness and forced position
  • swelling without pain and redness

Question 79

Question
Tache noire (black spot) at the site of the tick bite represents
Answer
  • painless ulcer covered with black (necrotic) crust
  • painless oval or round pink or red skin plaque> 5 cm
  • painful hot red plaque with raised edges

Question 80

Question
Which of the following findings IS NOT characteristic of infant meningitis?
Answer
  • bulging fontanelle, Lessage sign
  • distended abdomen
  • crie encephalique

Question 81

Question
The screening test for HIV infection is
Answer
  • anti HIV (ELISA)
  • viral RNA (PCR)
  • anti HIV (immunoblot)

Question 82

Question
The rash in Mediterranean spotted fever is
Answer
  • maculopapular
  • vesicular
  • erythematous

Question 83

Question
Which diseases in not vaccine preventable
Answer
  • Lyme borreliosis
  • Poliomyelitis
  • Measles

Question 84

Question
The most common electrolyte abnormalities in patients with diarrhea are
Answer
  • hyponatremia and hypokaliemia
  • hypercalcemia and hyperkaliemia
  • hypernatriemia and hyperchloremia

Question 85

Question
Acyclovir is recommended to which of following cases
Answer
  • Chicken pox - mandatory
  • Chicken pox in immunocompromised patients
  • Kaposi sarcoma

Question 86

Question
Which of the following statements regarding leptospirosis IS NOT true”
Answer
  • Leptospirosis is a biphasic illness with multiorgan involvement
  • Gentamycin is the antibiotic of choice
  • Infection is acquired during walking or bathing in rivers

Question 87

Question
At risk for development of Herpes Zoster are
Answer
  • adolescents (aged 11-19 years)
  • patients with HIV infection
  • newborns

Question 88

Question
Characteristic clinical manifestation of enteroviral infections is
Answer
  • Herpagina
  • Gingivostomatitis
  • Exudative pharyngitis

Question 89

Question
The rash in Scarlet fever is
Answer
  • small maculopapules predominantly in the axilar and inguinal regions
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribe

Question 90

Question
Inflammatory diarrhea is commonly caused by
Answer
  • Shigella sp., Campylobacter jejuni, Cl. difficile
  • Viruses, enterotoxigenic E. coli
  • S. aureus, B. cereus, most Salmonella sp.

Question 91

Question
When is ART warranted
Answer
  • For all HIV positive regardless of CD4 count
  • CD4<200 cells/µL
  • CD4< 350 cells/µL

Question 92

Question
In the case of infectious mononucleosis-like symptoms, it is important to consider
Answer
  • primary HIV infection
  • neoplasms
  • syphilis
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