Changing the way you learn

Question 1

Question

Choose the word or phrase from the list below that best completes this sentence. Pharmacokinetics can be described as ________________________

Answer

how the drug elicits it's effect in the body.
how the body handles a drug.
the composition of a drug.
the way in which a drug should be stored.

Question 2

Question

Choose the word or phrase from the list below that best completes this sentence. Drugs may act locally or systemically. Systemically means that the drug must enter ___________________ in order to be delivered to its site of action.

Answer

the brain
the circulation
the lymph nodes
the heart

Question 3

Question

Which equation can you use to calculate the amount of a drug that reaches the systemic circulation?

Answer

F x dose
F/dose
F - dose
F + (2 x dose)

Question 4

Question

Choose the word or phrase from the list below that best completes this sentence. Drugs administered as an IV injection have a bioavailability of _________.

Answer

Question 5

Question

What words make up the acronym ADME?

Answer

Administration
Absorption
Distribution
Dissolving
Making
Metabolism
Exit
Excretion

Question 6

Question

Choose the word or phrase from the list below that best completes this sentence. Generally in absorption, drugs move from an area of high concentration to a low concentration via ______________

Answer

osmosis.
active transport.
passive diffusion.

Question 7

Question

Choose the word or phrase from the list below that best completes this sentence. When drugs are being absorbed from an area of their low concentration to a higher concentration, they move by _____________

Answer

active transport.
osmosis.
passive diffusion.

Question 8

Question

Choose the word or phrase from the list below that best completes this sentence. Cell membranes are composed of a double layer of ____________________

Answer

proteins.
sugars.
phospholipids.
ions.

Question 9

Question

Water soluble drugs pass cell membranes easier than lipid soluble drugs.

Answer

True
False

Question 10

Question

Choose the word or phrase from the list below that best completes this sentence. The more _______________ a drug, the easier it is for the drug to be absorbed from the small intestine into the circulation.

Answer

lipid soluble
water soluble

Question 11

Question

Un-ionised drugs are lipid soluble. What does un-ionised mean?

Answer

The drug carries no charge.
The drug is negatively charged.
The drug is positively charged.
The molecule contains two opposing charges.

Question 12

Question

Choose the word or phrase from the list below that best completes this sentence. The small intestine has a large surface area due to it's large number of __________.

Answer

villi
cillia
hairs
cells

Question 13

Question

Choose the word or phrase from the list below that best completes this sentence. The larger the surface area for drug absorption, the _______ the absorption.

Answer

slower
quicker

Question 14

Question

Where does most drug absorption take place?

Answer

Stomach
Small Intestine
Large Intestine
Colon

Question 15

Question

The presence of food after a meal will slow gastric emptying.

Answer

True
False

Question 16

Question

Sometimes drugs are prescribed to be taken with food. Why might this be?

Answer

To lessen the side effects of a drug by preventing large concentrations from entering systemic circulation at the same time, ensuring a more gradual absorption due to gastric emptying.
To mask the bad taste of a drug that is taken orally.
To prevent local side effects, like irritation of the stomach lining, caused by drugs like NSAIDs.

Question 17

Question

Choose the word or phrase from the list below that best completes this sentence. Some drugs are absorbed from the small intestine into the _____________ and are transported directly into the liver.

Answer

renal portal vein
cranial portal vein
hepatic portal vein

Question 18

Question

What is the name of the process by which a drug is fully or partially metabolised by the liver, before entering the systemic circulation?

Answer

First pass metabolism
Liver/drug degradation
First past metabolism

Question 19

Question

Hypomotility of the GI tract may result in lower concentrations of drug entering the circulation.

Answer

True
False

Question 20

Question

Blood flow affects absorption.

Answer

True
False

Question 21

Question

Choose the word or phrase from the list below that best completes this sentence. A drug must reach it's site of action in ______________, in order to exert it's effect.

Answer

an adequate concentration
a membrane bound vesicle
a salt solution

Question 22

Question

Blood flow affects distribution.

Answer

True
False

Question 23

Question

Blood flow affects distribution. Organs that have high perfusion, e.g. heart, therefore receive drugs slowly.

Answer

True
False

Question 24

Question

Choose the word or phrase from the list below that best completes this sentence. Only ________ drug can cross plasma membranes and therefore exert an effect.

Answer

free
plasma protein bound
albumin bound

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Independent and Supplementary Prescribing

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	Created by offersforalice over 9 years ago